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The most important candidate genes for pancreatic stone formation
Stone formation is an important feature of chronic pancreatitis, especially tropical calcific pancreatitis (TCP), where the stones are large in size, highly irregular in shape and cause enormous tissue destruction.   view more (2007-11-14)

Vitamin K discovery may lead to new treatments for patients at risk from blood clots
Medical Research Council (MRC) scientists have discovered more about the role that vitamin K plays in the complicated process of how blood clots. Their work, published in Nature, may lead to new treatments for patients at risk from blood clots, including those who have had heart attacks, have... view more (2004-02-04)

New protein synthesis not essential to memory formation
New research from the University of Illinois challenges the premise that the brain must build new proteins in response to an experience for that experience to be recorded in long-term memory.    view more (2007-07-27)

NIST trumps the clumps: Making biologic drugs safer
Scientists at the National Institute of Standards and Technology (NIST) have developed a technique to measure the formation of clumps of proteins in protein-based pharmaceuticals.   view more (2008-07-24)

Lessons from yeast: A possible cure for Parkinson's disease?
Parkinson disease (PD) is a debilitating and lethal neurodegenerative disease, for which there is currently no cure. It is caused by the progressive loss of nerve cells that produce the chemical dopamine and is characterized by the accumulation of abnormal aggregates of a protein called alpha-syn... view more (2008-08-15)

NYU scientists identify critical protein complex in formation of cell cilia
An international team led by NYU Cancer Institute have identified a protein complex that regulates the formation of cilia, which are found on virtually all mature human cells and are essential to normal cell function.   view more (2008-08-20)

Researchers present Phase 2 clinical results for Acologix AC-100
Today, researchers from Acologix (Hayward, CA, USA), the University of California (San Francisco, USA), and the University of Connecticut (Simsbury, USA) will announce the results of a Phase 2 clinical trial of AC-100 (also known as Dentonin), reporting that it met its primary goal of stimulating... view more (2006-06-30)

The good and the bad of a potential Alzheimer's target
Research in fruit flies has shown that enhancing the production of a protein called neprilysin can reduce the formation of plaques and neuron death associated with Alzheimer's, at the expense of reducing the flies' lifespan.   view more (2008-06-30)

Competing proteins influence strength of tooth enamel
A gene critical to tooth formation expresses a protein that is then cleaved into two proteins with seemingly opposite functions, according to a USC-led team of dental researchers.   view more (2005-09-01)

Yeast model shows promise as Alzheimer's test
A century ago this month, German psychiatrist Alois Alzheimer formally described characteristics of the neurodegenerative disease which ultimately came to bear his name.   view more (2006-11-20)

Fruit fly helps identify protein critical to eggshell formation that may be pesticide target
The common fruit fly circling your week-old peach has helped scientists zero in on a protein critical to the insect's eggshell formation.   view more (2008-05-30)

Researchers discover a new genetic cause of Alzheimer's disease
Researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) connected to the University of Antwerp are the first to show that the quantity of amyloid protein in brain cells is a major risk factor for Alzheimer's disease.   view more (2006-04-20)

Notch controls bone formation and strength
Notch, a protein known to govern the determination of cell differentiation into different kinds of tissues in embryos, plays a critical role in bone formation and strength later in life, said researchers from Baylor College of Medicine in Houston in a report that appears online today in the journal... view more (2008-02-25)

Drawing a crowd: How progenitor cells are recruited to tumor blood vessels from the bone marrow
Cells within the bone marrow (progenitor cells) that express a protein called CD34 have been shown to leave the marrow and travel to sites of tissue injury to mediate repair.   view more (2006-02-24)

Shape Matters: NC State Scientists Characterize Structure of Protein Involved in Preventing Alzheimer's, Huntington's Diseases
Scientists at North Carolina State University have effectively lifted the veil from an important protein that is linked to the prevention of neurodegenerative diseases like Alzheimer's and Huntington's.   view more (2006-07-26)

p53, tumor suppression and aging
In the January 1 issue of Genes & Development, Dr. Mary Ellen Perry and colleagues validate the p53 inhibitor, Mdm2, as a promising target for cancer therapies.   view more (2006-01-03)

Researchers discover new form of cancer gene regulation
The Quaking gene, first described as a mutation in mice that causes rapid tremor, is thought to suppress tumor formation and protect humans from cancer.   view more (2005-11-08)

Unexpected similarities between raindrops and proteins
Raindrops and proteins seem to have a lot in common. This has been shown in a new study by scientists at Ume'å University in Sweden. The principle behind the formation of raindrops is very similar to how proteins fold. This knowledge is vital to our understanding of neurodegenerative diseases... view more (2004-05-26)

Enzyme promotes fat formation
The enzyme TPPII may contribute to obesity by stimulating the formation of fat cells, suggests a study in EMBO reports this week. The enzyme, TPPII, has previously been linked to making people feel hungry, but Jonathan Graff and colleagues now show that it may be even more deeply involved in... view more (2007-10-12)

Physics provides new insights on cataract formation
Using the tools and techniques of soft condensed matter physics, a research team in Switzerland has demonstrated that a finely tuned balance of attractions between proteins keeps the lens of the eye transparent, and that even a small change in this balance can cause proteins to aggregate and de-mix.   view more (2007-11-12)

New Cancer Gene Discovered
Researchers at the OU Cancer Institute have identified a new gene that causes cancer. The ground-breaking research appears Monday in Nature's cancer journal Oncogene.   view more (2008-05-09)

Viral oncoprotein inactivation of p53
A group of scientists led by USC researcher Dr. Xiaojiang Chen lend structural insight into tumor suppressor inactivation by a viral oncoprotein.   view more (2006-09-01)

Researchers find cause of frontotemporal dementia
Frontotemporal Dementia (FTD) is the second major form of dementia.   view more (2006-07-17)

MU researchers find clue to cataract formation
It is the No. 1 line-item cost of Medicare reimbursement and affects more than 20 million people in the United States. Cataracts, which can have devastating effects on the eye, affect 42 percent of the population between the ages of 70 and 80, and 68 percent of the population over the age of 80.   view more (2008-04-18)

Researchers offer clues to how leaf patterns are formed
Pick up a leaf and it is hard not to notice the pattern made by the veins. For years, biologists, mathematicians and even poets and philosophers have tried to decipher the rules and regulations behind those varied designs and now new research published in part at the University of Alberta offers a... view more (2006-06-16)
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