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LSUHSC research may benefit diabetes by increasing understanding of how to control islet cell growth
Michael Lan, PhD, Professor of Pediatrics and Genetics at LSU Health Sciences Center New Orleans, is the senior author of a paper revealing the molecular mechanism of how a protein determines the fate of the cells that make and release insulin. view more (2009-02-18)
GUMC discovery highlights new direction for drug discovery
In a discovery that rebuffs conventional scientific thinking, researchers at Georgetown University Medical Center (GUMC) have discovered a novel way to block the activity of the fusion protein responsible for Ewing's sarcoma, a rare cancer found in children and young adults. view more (2009-07-06)
Integrins as receptors give insight into rotavirus and diarrhea
Eleven years ago, Dr. Mary Estes of Baylor College of Medicine and her colleagues discovered the first viral enterotoxin, rotavirus NSP4, a toxic protein that affects the intestines, causing diarrhea. view more (2008-07-01)
Viral oncoprotein inactivation of p53
A group of scientists led by USC researcher Dr. Xiaojiang Chen lend structural insight into tumor suppressor inactivation by a viral oncoprotein. view more (2006-09-01)
The Institut Curie and Hybrigenics receive 2.4 million euros from the Ministry of Industry for the GenHomme research and technological innovation network
Nicole Fontaine, the minister for industry, will today officially award a subsidy to the functional proteomics company Hybrigenics and to the Institut Curie, a center dedicated to cancer research and treatment. Nicole Fontaine thus declares her conviction that the strengthening of the synergy between private and public research should be at the... view more... (2003-03-19)
On the Trail of a Vaccine for Lyme Disease: Yale Researchers Target Tick Saliva
A protein found in the saliva of ticks helps protect mice from developing Lyme disease, Yale researchers have discovered. The findings, published in the November 19 issue of Cell Host & Microbe, may spur development of a new vaccine against infection from Lyme disease, which is spread through tick bites. view more (2009-11-20)
SUMO protein guides chromatin remodeler to suppress genes
In an in vitro study, led by Grace Gill, PhD, Tufts University School of Medicine, researchers discovered how a protein called SUMO (Small Ubiquitin-related Modifier) guides an enzyme complex that alters the structure of chromatin to regulate expression of genes. view more (2009-04-28)
Jefferson researchers' discovery may change thinking on how viruses invade the brain
A molecule thought crucial to ferrying the deadly rabies virus into the brain, where it eventually kills, apparently isn't. view more (2007-04-20)
Single-stranded DNA-binding protein is dynamic, critical to DNA repair
Researchers report that a single-stranded DNA-binding protein (SSB), once thought to be a static player among the many molecules that interact with DNA, actually moves back and forth along single-stranded DNA, gradually allowing other proteins to repair, recombine or replicate the strands. view more (2009-10-22)
Minimum information standards -- all for 1 and 1 for all
Three papers published by EMBL scientists and their collaborators will make it much easier to share and compare information from large-scale proteomics data. The papers are published in Nature Biotechnology on 8th and 26th August. view more (2007-08-27)
Computational microscope peers into the working ribosome
Two new studies reveal in unprecedented detail how the ribosome interacts with other molecules to assemble new proteins and guide them toward their destination in biological cells. view more (2009-11-24)
Malaria mechanism revealed
By determining the molecular structure of a protein that enables malaria parasites to invade red blood cells, researchers have uncovered valuable clues for rational antimalarial drug design and vaccine development. view more (2005-07-29)
Researchers identify mechanism used by gene to promote metastasis in human cancer cells
Virginia Commonwealth University Institute of Molecular Medicine and VCU Massey Cancer Center researchers have discovered how a gene, melanoma differentiation associated gene-9/syntenin (mda-9/syntenin), interacts with an important signaling protein to promote metastasis in human melanoma cells, a discovery that could one day lead to the... view more... (2008-09-30)
How Safe Are Your Foundations?
Catastrophic failure of the foundations of a large structure such as an oil drilling or exploration platform are costly in terms of wasted time, inconvenience, environmental damage or monetary value, but add to this the potential cost of the loss of human life and the confidence of the public in the industry falls rapidly. Consideration of all of... view more... (2004-05-13)
New proteomics research promises to revolutionize biomedical discovery
Human cells function through the concerted action of thousands of proteins that control their growth and differentiation. Yet, the specific function of most human proteins remains either unknown or poorly characterized. view more (2007-07-20)
Discovery about obesity drug helping scientists develop new cancer treatments
Based on their surprising discovery that an obesity drug can kill cancer cells, scientists at Wake Forest University School of Medicine have made a new finding about the drug's effects and are working to design more potent cancer treatments. view more (2007-07-09)
Scripps research study shows humans and plants share common regulatory pathway
The study was published in an advance online edition of the Proceedings of the National Academy of Sciences during the week of April 9, 2007. view more (2007-04-10)
GIANT-Coli: A novel method to quicken discovery of gene function
Think researchers know all there is to know about Escherichia coli, commonly known as E. coli? Think again. "E. coli has more than four thousand genes, and the functions of one-fourth of these remain unknown," says Dr. Deborah Siegele, a biology professor at Texas A&M University whose laboratory specializes in carrying out research... view more... (2008-08-07)
OHSU Cancer Institute researchers find connection between protein, prognosis in breast cancer
Oregon Health & Science University Cancer Institute researchers have found that a tumor protein present in an aggressive form of breast cancer is related to a poor prognosis. view more (2008-04-14)
Microbes and Man Research Programme starting up
Main focus on interaction between microbes and man The newly launched Academy of Finland Research Programme on Microbes and Man (MICMAN) is aimed at producing new information on the interaction between microbes and man and at making use of that information for purposes of maintaining health and preventing and treating illnesses. The programme is... view more... (2003-02-03)
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