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Molecular 'on/off switch' controls immune defenses against viruses
Much like flipping a light switch, the hepatitis C virus turns on human immune defenses upon entering the body but also turns off those defenses by manipulating interaction of key cellular proteins, UT Southwestern Medical Center researchers have found. view more (2006-12-26)
Crucial progress in understanding Fragile X mental retardation protein
Researchers in the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale School of Medicine have identified a new regulatory target for the Fragile X mental retardation protein (FMRP), laying the groundwork for possible new treatments for Fragile X syndrome(FXS), the leading inherited form of mental retardation. view more (2007-06-07)
Abnormal glutamine repeats interfere with key transcription factor, leading to neurodegeneration
Although repeating sequences of three nucleotides encoding some of the bodies' 20 amino acids are a normal part of protein composition, abnormal expansion of trinucleotide repeats is the known cause of multiple inherited neurodegenerative disorders, including Huntington disease. view more (2007-11-14)
Delicate Relation between Single Spins
Probing the magnetic interaction between single atoms is no longer a dream. Using a scanning tunnelling microscope, the interaction of the spins of two neighbouring cobalt atoms adsorbed at a copper surface has been measured as a function of their distance with atomic precision. view more (2007-03-05)
Instruction Manuals: First Text then Pictures
Delft research on efficiency of text, images and animations in instruction manuals Instruction Manuals: First Text then Pictures In instruction manuals, the use of text is most efficient for short-term learning and images are most efficient for the longer term. This is one of the conclusions from the thesis of Piet Westendorp, which he defended on... view more... (2002-06-11)
Protein structure determined in living cells
The function of a protein is determined both by its structure and by its interaction partners in the cell. Until now, proteins had to be isolated for analyzing them. view more (2009-03-05)
Mayo discovers link between Huntington's and abnormal cholesterol levels in brain
Mayo Clinic researchers have discovered a protein interaction that may explain how the deadly Huntington's disease affects the brain. view more (2006-12-04)
Researchers measure carbon nanotube interaction
Carbon nanotubes have been employed for a variety of uses including composite materials, biosensors, nano-electronic circuits and membranes. view more (2007-10-17)
Dangerous Interaction Between The Antidepressant Fluvoxamine (Fevarin, Faverin, Luvox) And The Muscle Relaxant Tizanidine (Sirdalud, Zanaflex)
Researchers from Finland have found that the antidepressant drug fluvoxamine (brand names Fevarin, Faverin, Luvox etc.) drastically increases the concentrations of tizanidine (Sirdalud, Zanaflex) in blood. Concomitant use of fluvoxamine and tizanidine results in severe and prolonged decrease in blood pressure and greatly enhanced central nervous... view more... (2004-04-06)
Bacterial protein mimics host to cripple defenses
Like a wolf in sheep's clothing, a protein from a disease-causing bacterium slips into plant cells and imitates a key host protein in order to cripple the plant's defenses. view more (2005-12-23)
Lead exposure plus high blood pressure may impair mental ability
Exposure to lead in early childhood and adolescence may contribute to hypertension-related decline that can impair a person's cognitive abilities, according to a new study presented at the 2005 American Heart Association's High Blood Pressure Research meeting. view more (2005-09-26)
Building a Better Protein
Proteins are widely viewed as a promising alternative to synthetic chemicals in everything from medications to hand lotion. The naturally occurring molecules have been shown to be more efficient and effective than many of the most sophisticated chemical compounds on the market. view more (2009-02-24)
Learning How SARS Spikes Its Quarry
Researchers have determined the first detailed molecular images of a piece of the spike-shaped protein that the SARS virus uses to grab host cells and initiate the first stages of infection. view more (2005-09-16)
Human immunodeficiency virus (HIV) treatment
Russian researchers have developed a medication capable of protecting against various human immunodeficiency virus (HIV) strains. Their effort has been supported by the International Scientific Technical Center. Intense search for efficacious human immunodeficiency virus treatment carried out by scientific laboratories worldwide has not yet... view more... (2004-01-30)
University to develop new therapeutics for cancer
Dr Roger Barraclough, from the School of Biological Sciences, is working on a new protein which causes some cancer cells to spread around the body. This protein is being developed to assist in improving the management of breast cancer. view more (2006-07-28)
Key protein that may cause cancer cell death identified
Researchers at A*STAR's Institute of Molecular and Cell Biology (IMCB) have become the first to discover and characterize a human protein called Bax-beta (Baxβ), which can potentially cause the death of cancer cells and lead to new approaches in cancer treatment. view more (2009-01-20)
Scientists discover how to send insects off the scent of crops
Biotechnology and Biological Sciences Research Council (BBSRC)-funded research, published this week in Chemical Communication, describes how scientists have discovered molecules that could confuse insects' ability to detect plants by interfering with their sense of smell. This could reduce damage to crops by insect pests and contribute to food... view more... (2009-09-24)
Novel method to reveal drug targets
Wellcome Trust Sanger Institute scientists have developed a new large-scale method to identify the interactions between proteins that are a major target for therapeutic intervention. view more (2008-02-25)
Matrix protein key to fighting viruses
Researchers from Durham University's Centre for Bioactive Chemistry are developing methods that show how proteins interact with cell membranes when a virus strikes. view more (2009-04-29)
Mixing large doses of both acetaminophen painkiller and caffeine may increase risk of liver damage
Consuming large amounts of caffeine while taking acetaminophen, one of the most widely used painkillers in the United States, could potentially cause liver damage, according to a preliminary laboratory study reported in the Oct. 15 print issue of ACS' Chemical Research in Toxicology, a monthly journal. view more (2007-09-26)
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