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'Fishy' clue helps establish how proteins evolve
Three billion years ago, a "new" amino acid was added to the alphabet of 20 that commonly make up proteins in organisms today. Now researchers at Yale and the University of Tokyo have demonstrated how this rare amino acid - and, by example, other amino acids - made its way into the menu for protein synthesis. view more (2009-01-28)
MIT biologists solve vitamin puzzle
Solving a mystery that has puzzled scientists for decades, MIT and Harvard researchers have discovered the final piece of the synthesis pathway of vitamin B12—the only vitamin synthesized exclusively by microorganisms. view more (2007-03-23)
UT Southwestern researchers find gene mutation that leads to 'broken hearts'
Researchers at UT Southwestern Medical Center have identified a group of fruit fly gene mutations responsible for "broken hearts" in the embryonic stages of development, a discovery that could help identify genes that cause human heart defects. view more (2006-07-24)
Scientists unlock more secrets of HIV and SARS
UK scientists have cracked one of the key biological processes used by viruses such as HIV and SARS when they replicate. view more (2006-05-11)
Montreal researchers probe the genetic basis of memory
A group of Montreal researchers has discovered that GCN2, a protein in cells that inhibits the conversion of new information into long-term memory, may be a master regulator of the switch from short-term to long-term memory. view more (2005-08-31)
Study finds more effective treatment for pneumonia following influenza
Scientists at St. Jude Children's Research Hospital have demonstrated a more effective treatment for bacterial pneumonia following influenza. view more (2009-01-09)
Fuel From Natural Gas
The scientists from the Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, won Golden Medal and a bonus grant at the 49th World Exhibition of Invention, Research and Industrial Innovation ("Eureka") in Brussels for their work "Synthesis of dimethyl ether". The dateless dream of several generations of chemists has finally... view more... (2002-02-08)
Early-stage gene transcription creates access to DNA
A gene contained in laboratory yeast has helped an international team of researchers uncover new findings about the process by which protein molecules bind to control sequences in genes in order to initiate gene expression, according to findings reported in the journal Nature. view more (2008-10-07)
How protein-rich diets curb hunger
Researchers have uncovered new evidence to explain the observation that diets rich in protein stunt the appetite, according to a report in the November Cell Metabolism. view more (2005-11-09)
Cloning techniques produce FDA-approved antibiotic
The successful synthesis of an antibiotic in a non-native host has provided a team of researchers at the University of Illinois at Urbana-Champaign with the potential for developing new treatments for bacterial infections. view more (2006-11-28)
ESRF lightsource helps tailoring new treatments against asthma
Researchers from Sweden and France have deciphered the crystal structure of a human membrane protein which has a major influence on the development of asthma. view more (2007-08-03)
Second low-oxygen pathway hints at cancer, cardiovascular disease physiology
Researchers at the University of Pennsylvania School of Medicine have identified a second molecular pathway that promotes cell survival in low-oxygen conditions. view more (2006-02-17)
Fragile X retardation syndrome corrected in mice
Researchers working with mice have significantly alleviated a wide range of abnormalities due to fragile X syndrome by altering only a single gene, countering the effects of the fragile X mutation. view more (2007-12-20)
Proteins that stop a major signaling pathway can also generate new proteins
Duke University Medical Center researchers have recently discovered that a crucial communications pathway in cells not only stops cells from making proteins, it also makes them go. view more (2008-04-25)
To sleep, perchance to dream: New insight into melatonin production
In the April 1 issue of G&D, a Korean research team led by Dr. Kyong-Tai Kim (Pohang University) describes how melatonin production is coordinated with the body's natural sleep/wake cycles. view more (2007-04-02)
Mechanism controlling DNA damage response has potential novel medical applications
Investigators at St. Jude Children's Research Hospital have discovered a previously unrecognized mechanism that controls a key protein linked to the cell's response to stress-a finding that holds promise for new ways to enhance cancer therapies or protect cells from dying after exposure to damaging chemicals or radiation. view more (2005-10-07)
A better way to copy DNA
Scientists have developed a new method for DNA amplification that could replace the polymerase chain reaction (PCR), a technique that is invaluable for both medical diagnostics and basic research but which is confined to the laboratory. In the August issue of EMBO reports, Huimin Kong and colleagues at New England Biolabs (Beverly, MA, USA)... view more... (2004-07-14)
Fatostatin' is a turnoff for fat genes
A small molecule earlier found to have both anti-fat and anti-cancer abilities works as a literal turnoff for fat-making genes, according to a new report in the August 28th issue of the journal Chemistry and Biology, a Cell Press journal. view more (2009-08-28)
Soy protein reduces effects of diabetes on liver
A group of researchers from Mexico has discovered that a diet rich in soy protein may alleviate fatty liver, a disease which often accompanies diabetes. view more (2005-09-07)
Novel mechanism for DNA replication discovered
Since the discovery of the structure of DNA by James Watson and Francis Crick in 1953, the paradigm for DNA replication has stated that the DNA itself codes for the appropriate pairings for replication. view more (2005-09-30)
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