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Experimental anti-cancer synthetic molecule targets tumor cell growth and angiogenesis
A recent study conducted by three French CNRS (Centre National de la Recherche Scientifique) laboratories describes a new candidate anti-cancer drug, named HB-19. view more (2008-06-18)
Fox Chase study sheds light on cancer susceptibility and disease involving bone-marrow failure
Defective protein production can occur in cells even when the genes controlling those proteins are normal. view more (2006-05-12)
Research elucidates mechanism by which gene expression may be altered in drug addiction
Dr. Judith A. Potashkin, Ph.D. and her colleagues at Rosalind Franklin University of Medicine and Science recently completed a study investigating one of the changes in gene expression that occurs when individuals take addictive drugs. view more (2007-09-05)
Chemists synthesize herbal alkaloid
The club moss Lycopodium serratum is a creeping, flowerless plant used in homeopathic medicine to treat a wide variety of ailments. view more (2009-04-16)
Drought reduces nitrogen-fixing in legumes
In drought conditions, the capacity for retaining carbon in legume nodules is limited and this may be the reason why there is a drop in nitrogen-fixing in legumes under these conditions. This was the conclusion of Mar'a Dolores G'Ħlvez in defending her PhD thesis at the Public University of Navarre. Her PhD was entitled, "Nodule metabolism... view more... (2005-02-04)
Researchers find 'surprising link' leads toward a new antibiotic
As the best drugs become increasingly resistant to superbugs, McMaster University researchers have discovered a completely different way of looking for a new antibiotic. view more (2009-05-29)
New oxidation methods streamline synthesis of important compounds
One of the fundamental challenges facing organic synthesis in the 21st century is the need to significantly increase the efficiency with which carbon frameworks can be constructed and functionalized. view more (2007-08-03)
Scientists Find Missing Link to Understand How Plants Make Vitamin C
Vitamin C is possibly the most important small molecule whose biosynthetic pathway remained a mystery. That is until now. view more (2007-04-30)
Another type of nanotube, a how-to guide to making bamboo-structured carbon nanotubes
Nanotechnology is area if science that has recently captured the attention of people all around the world. At the heart of the nanotechnology revolution are carbon nanotubes, amazing materials with astonishing properties. They have applications in most fields, with new possibilities emerging regularly. view more (2007-11-26)
Singapore scientists synthesize gold to shed light on cells' inner workings
Highly fluorescent gold nanoclusters for sub-cellular imaging have been synthesized by researchers at the Institute of Bioengineering and Nanotechnology (IBN). view more (2009-04-16)
Clinical tests begin on medication to correct Fragile X defect
NIH-supported scientists at Seaside Therapeutics in Cambridge, Mass., are beginning a clinical trial of a potential medication designed to correct a central neurochemical defect underlying Fragile X syndrome, the most common inherited cause of intellectual disability. view more (2009-11-03)
Discovery of new molecular tools for biosynthesis could lead to important advances in use of pectin in medicine, agriculture and industry
Most people know pectin as a common household gelling agent in making jams and jellies, but its uses are vast. It has anticancer properties, for instance, and may have a role in important biological functions including plant growth and development and defense against disease. view more (2006-03-22)
Research shows aerobic exercise helps maintain muscle in elderly
Why do older people tend to lose muscle mass and grow frail? One important factor identified by medical science is the reduced ability of the elderly to respond to the muscle-building stimulus of the hormone insulin. view more (2007-05-31)
'Birth control' for centrioles
Like DNA, centrioles need to duplicate only once per cell cycle. Rogers et al. uncover a long-sought mechanism that limits centriole copying, showing that it depends on the timely demolition of a protein that spurs the organelles' replication. view more (2009-01-26)
UC Santa Barbara scientists clarify molecular basis of interferon action
Scientists at the University of California, Santa Barbara have made a significant discovery relating to viral infections in humans. view more (2007-07-20)
Limiting fructose may boost weight loss, UT Southwestern researcher reports
One of the reasons people on low-carbohydrate diets may lose weight is that they reduce their intake of fructose, a type of sugar that can be made into body fat quickly, according to a researcher at UT Southwestern Medical Center. view more (2008-07-24)
Lost in translation
The enzyme machine that translates a cell's DNA code into the proteins of life is nothing if not an editorial perfectionist. view more (2009-01-08)
New discoveries about neuron plasticity linked to learning and memory
Neurons experience large-scale changes across their dendrites during learning, say neuroscientists at The University of Texas at Austin in a new study that highlights the important role that these cell regions may play in the processes of learning and memory. view more (2005-11-02)
Researchers Discover Master Metabolism Regulator with Links to Obesity, Heart Disease, and Malnutrition
Two biologists at Penn State have discovered a master regulator that controls metabolic responses to a deficiency of essential amino acids in the diet. view more (2007-02-07)
The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site
Synopsis: Two papers from Woods and colleagues describe novel roles for members of the dual specificity tyrosine phosphorylated and regulated kinase (DYRK) family. In one, DYRK1A is shown to phosphorylate a novel site in the transcription factor FKHR (a forkhead protein) regulating its nuclear presence and transcriptional activity. In the second... view more... (2001-04-24)
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