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Left-handed molecules make better drugs – bacteria are more efficient drug factories
Using bacteria as factories to produce drugs could be safer, cheaper and more efficient than traditional chemical manufacturing methods, experts heard today (Wednesday 12 September 2001) during the bi-annual meeting of the Society for General Microbiology at the University of East Anglia. “Chiral drugs are important in the treatment of many... view more... (2001-09-07)
Impact of elevated homocysteine levels on vision under study
Homocysteine, an amino acid believed to contribute to heart attack, stroke and dementia, likely also is a player in retinal damage and vision loss, researchers say. view more (2007-10-16)
An infectious agent of deception, exposed through proteomics
Salmonella bacteria, infamous for food poisoning that kills hundreds of thousands worldwide, infect by stealth. view more (2006-09-29)
Organic & Biomolecular Chemistry
First Advance Articles Now Available Free Online The first issue of Organic & Biomolecular Chemistry, formed from the merger and strategic development of Perkin Transactions 1 & 2, will be published on 10 January 2003. The electronic version will go up on 23 December 2002. Barbara Imperiali, Francois Diederich, Ben Feringa and Chi-Huey... view more... (2002-12-05)
Textbook explanation of mRNA translation may need rethinking
Our understanding of how messenger RNAs are translated into proteins is challenged by new research published today in the Open Access journal Journal of Biology. view more (2005-06-27)
Mayo Clinic identifies treatment target for liver cancer recurrence and survival
Deadly and difficult to treat, liver cancer has long resisted attempts by researchers to develop ways to prolong life and prevent recurrence. view more (2008-04-11)
Magic Beans — Anti-obesity soya could help prevent diabetes
A diet rich in black soya beans could help control weight, lower fat and cholesterol levels, and aid in the prevention of diabetes, reports Lisa Richards in Chemistry & Industry, the magazine of the SCI. view more (2007-02-26)
Gene mutation responsible for premature skin aging disease identified
In the new print issue of Nature Genetics, scientists in Singapore and Germany report that mutations in the PYCR1 gene cause the rare genetic condition that results in premature skin aging and that is known as "wrinkly skin syndrome." view more (2009-09-01)
New reagent delivers a chemical breakthrough at FSU
"Build a better mousetrap," the saying goes, "and the world will beat a path to your door." In the complex field of organic chemistry, that path leads to Florida State University, where a newly developed substance could make the jobs of scientists throughout the world a little easier as they work to develop new drugs and other... view more... (2007-03-16)
Scientists capture the first image of memories being made
The ability to learn and to establish new memories is essential to our daily existence and identity; enabling us to navigate through the world. view more (2009-06-19)
RNA Toxicity Contributes to Neurodegenerative Disease, University of Pennsylvania Scientists Say
Expanding on prior research performed at the University of Pennsylvania, Penn biologists have determined that faulty RNA, the blueprint that creates mutated, toxic proteins, contributes to a family of neurodegenerative disorders in humans. view more (2008-05-22)
Study of protein folds offers insight into metabolic evolution
Researchers at the University of Illinois have constructed the first global family tree of metabolic protein architecture. Their approach offers a new window on the evolutionary history of metabolism. view more (2007-05-21)
New prion protein discovered by Canadian scientists may offer insight into mad cow disease
Scientists have discovered a new protein that may offer fresh insights into brain function in mad cow disease. "Our team has defined a second prion protein called 'Shadoo', that exists in addition to the well-known prion protein called 'PrP' " said Professor David Westaway, director of the Centre for Prions and Protein Folding Diseases... view more... (2007-08-17)
Bringing astronomy into sharper focus
Scientists from the University of Cambridge's Astrophysics Group have today (21 June 2002) announced a collaboration with teams based in New Mexico, Puerto Rico and at the Naval Research Laboratory in Washington DC to design, install and operate a novel type of astronomical telescope for ultra-high angular resolution observations of stars,... view more... (2002-06-21)
Boehringer Ingelheim enters into multi-target drug discovery collaboration with Morphochem.
Morphochem AG, a leader in the evolutionary discovery of small molecule drugs announced that it has entered into a research collaboration with Boehringer Ingelheim, a leading pharmaceutical company with a focus on human pharmaceuticals and animal health. Morphochem will apply its drug discovery engine MOREsystem™ to the discovery and... view more... (2004-02-04)
New collaboration between Amersham Biosciences and Affibody increases potential in protein purification
Under the agreement, the two companies will work to develop affinity-based products for use in the production processes for protein-based pharmaceuticals. The development of these products will be based on Affibodies™, a novel class of small, robust affinity proteins designed to bind desired protein targets. Financial details of the... view more... (2002-03-06)
New evidence shows Rituximab halts damage to joints
New data, presented today at the Annual European Congress of Rheumatology show for the first time that a rheumatoid arthritis (RA) treatment, rituximab, is able to significantly inhibit the structural damage to joints caused by RA in patients who have long-standing disease and an inadequate response to one or more TNF (Tumour Necrosis Factor)... view more... (2006-06-23)
Brain study may lead to improved epilepsy treatments
Using a rodent model of epilepsy, researchers found one of the body's own neurotransmitters released during seizures, glutamate, turns on a signaling pathway in the brain that increases production of a protein that could reduce medication entry into the brain. view more (2008-04-15)
Making sense of the human genome: researchers characterize a crucial family of signaling proteins in the human genome
In this month's Genome Biology, Mitch Kostich and colleagues from the Schering-Plough Research Institute (NJ, USA) have identified and mapped an important group of molecules known as protein kinases. These molecules are central to the communication of information both within and between cells, in a process known as cell signaling. Defective... view more... (2002-08-23)
Cold Spring Harbor Protocols features methods for analyzing protein interactions
Cold Spring Harbor Protocols, an online journal that publishes methods used in a wide range of biology laboratories, has added over 40 new peer-reviewed protocols to its archive today. view more (2006-09-11)
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