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Elastic interactions of membrane proteins
Cellular survival relies crucially on the ability to receive and communicate signals from and to the outside world. A major part of this regulation and communication is performed by proteins within the membrane of a cell. view more (2007-05-04)
Light shed on vision and hearing disorders
The most common hereditary condition that affects both hearing and vision is Usher Syndrome (USH). In the next issue of The EMBO Journal, scientists at the Institut Pasteur report on studies that have established the first link between Myosin VIIa, Cadherin 23 and Harmonin b. These three proteins were previously known to be involved in the... view more... (2002-12-16)
Candidate markers for gastric cancer
The sequencing of the human genome has opened the door for proteomics by providing a sequence-based framework for mining proteomes. view more (2008-10-29)
Protein research could lead to new meningitis vaccine
New technology is leading to a vaccine against Group B Streptococci (GBS), a common cause of meningitis as well as a frequent cause of pneumonia in newborns. Key proteins have been found that can kick-start the immune system to fight these bacteria, scientists heard today (Tuesday 09 April 2002) at the spring meeting of the Society for General... view more... (2002-04-03)
How actin networks are actin'
Dynamic networks of growing actin filaments are critical for many cellular processes, including cell migration, intracellular transport, and the recovery of proteins from the cell surface. view more (2008-01-03)
Important new model shows how proteins find the right DNA sequences
Researchers at Uppsala University and Harvard University have collaboratively developed a new theoretical model to explain how proteins can rapidly find specific DNA sequences, even though there are many obstacles in the way on the chromosomes. view more (2009-03-16)
ETH Researchers Open New Perspectives for Biotechnology
Metabolic and biochemical reactions are basically the same in all living beings, or at least comparable. The genetic codes of all living beings, that is to say of bacteria, plants, fungii and animals, are made up of the same set of building blocks. Human genes are therefore correctly translated into the corresponding proteins even by bacteria. The... view more... (2002-11-28)
Protein interaction network can respond Helicobacter pylori infection?
Helicobacter pylori (H pylori) is a gram negative bacterium which infects about 50% of the world population. H pylori colonization causes a strong systemic immune response. view more (2009-10-16)
The precise role of seminal proteins in sustaining post-mating responses in fruit flies
Successful reproduction is critical to pass genes to the next generation. In sexually reproducing organisms, sperm enter the female with seminal proteins that are vital for fertility. view more (2007-12-18)
£11.5m for new structural proteomics research programmes
BBSRC has announced two new research programmes that together will receive £11.5m under the Structural Proteomics of Rational Targets Initiative (SPoRT). The Membrane Protein Structure Initiative (MPSI), a consortium of experienced membrane research groups at universities and institutes across the UK and led by the University of Glasgow,... view more... (2004-06-17)
Yale researchers make cell biology quantitative
Yale researchers have reported a method to count the absolute number of individual protein molecules inside a living cell, and to measure accurately where they are located, two basic hurdles for studying biology quantitatively. view more (2005-10-20)
New technique can be breakthrough for early cancer diagnosis
Early detection of disease is often critical to how successful treatment can be. Therefore, the development of new methods of diagnosis is a hot research field, where every small step is of great importance. In an article in the latest issue of Molecular & Cellular Proteomics, Uppsala University researchers describe a technique that the... view more... (2007-09-12)
Plastic-Protein Hybrids
Functional membrane proteins in a block copolymer matrix Biological membranes form a fluid matrix, in which proteins "swim". Many of these membrane proteins are of interest for both pharmacological and biotechnological applications - for example, they are under consideration as biosensors for the rapid screening of pharmaceutical agents.... view more... (2000-12-11)
The structure of resistance
A team of scientists from the University Paris Descartes has solved the structure of two proteins that allow bacteria to gain resistance to multiple types of antibiotics, according to a report in EMBO reports this month. view more (2008-02-25)
TANGO - towards faster prognosis of Alzheimer's and Parkinson's diseases?
A large number of diseases - including Alzheimer's disease, Parkinson's disease, and mad cow disease - are the result of proteins that erroneously assume the wrong shape, causing them to stick to each other. This phenomenon is perceptible, but up to now it has been difficult to predict. Researchers from the Flanders Interuniversity Institute for... view more... (2004-09-13)
Statistics are insufficient for study of proteins' signal system
Ten years ago great attention was attracted by the discovery that it was possible to demonstrate signal transfer in proteins using statistical methods. In an article in the journal Proceedings of the National Academy of Science (PNAS) Uppsala researchers are now presenting results of experiments that contradict the theory. view more (2008-03-27)
Stress causes parodontis
Under stress, major proteins get actively destroyed in the parodentium. According to biologists' data, chronical stress inhibits the osseous tissue maturing process and intensifies decomposition of collagen protein and proteoglycans with the animals non-resistant to stress. Stress intensifies hydrolysis of proteins, which make the basis of the... view more... (2003-09-26)
Unstable proteins can cause premature ageing
The normal ageing process has long been linked to problems with cell respiration, the process through which the cells extract energy from nutrients. view more (2009-08-06)
1 step closer to green chemistry and improved pharmaceuticals
Proteins are the workhorses of our cells. They help to digest our food, are at the core of our immune system, and literally shape our body from top to toe. view more (2008-06-25)
New discovery may improve treatment of neurodegenerative diseases and type 2 diabetes
The discovery opens the way for new drugs to be designed to treat Parkinson's, type 2 diabetis, Alzheimer's and Creuzfeldt-Jacob disease. view more (2005-12-15)
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