Pulmonary Fibrosis Current Events | Pulmonary Fibrosis News | 5
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Scientists identify novel way to prevent cardiac fibrosis
In a study that points to a new strategy for preventing or possibly reversing fibrosis - the scarring that can lead to organ and tissue damage - researchers at the University of California, San Diego School of Medicine have determined that a molecule called Epac (Exchange protein activated by cAMP1), plays a key role in integrating the body's pro-... view more... (2008-04-23)
Tracking Cystic Fibrosis with Mice: DFG fellow develops an animal model for the disease
Cystic fibrosis, also known as mucoviscidosis, is one of the most common genetic diseases with a fatal outcome in western Europe. The disease is caused by a defective gene that affects the salt and fluid composition of respiratory tract secretions. As a result, they become highly viscous. The viscous mucous then clumps in the smaller lung... view more... (2004-04-26)
Clues to gene expression in cystic fibrosis will guide research
Genetics tests could help provide cystic fibrosis (CF) patients with targeted treatment in future, pilot study authors suggest. Results from a French clinical trial published today in BMC Medicine show how a small percentage of CF sufferers with a rare genetic stop mutation responded positively to gentamicin treatment. view more (2007-03-29)
U-M researchers find those with severe H1N1 at risk for pulmonary emboli
University of Michigan researchers have found that patients with severe cases of the H1N1 virus are at risk for developing severe complications, including pulmonary emboli, according to a study published today in the American Journal of Roentgenology. view more (2009-10-15)
Who is the arch-criminal in the development of hepatopulmonary syndrome?
The hepatopulmonary syndrome (HPS) develops when an arterial oxygenation deficiency occurs due to intra-pulmonary vascular dilatations that are often associated with severe hepatic disease. HPS occurs in 15-20% of patients with liver cirrhosis undergoing evaluation for orthotopic liver transplantation. view more (2007-12-20)
Gene may inhibit smokers from quitting
Smokers with a particular genetic make-up (genotype) may find it harder to give up their habit, suggest Japanese researchers in Thorax. The presence of a CYP2A6del allele, a specific form of the gene involved in processing nicotine in the body, may inhibit smokers from quitting, but it also seems to protect against the development of pulmonary... view more... (2003-06-27)
Putting a stop to antibiotic resistance with new drugs from seaweed
Scientists have found a new way to prevent life-threatening infections not by killing the bacteria but by preventing them from talking to each other, according to research published today in the journal Microbiology. We`ve found that a group of chemicals called furanones can prevent the build up of communities of bacteria on surfaces such as... view more... (2001-12-21)
Researchers identify molecule that causes destructive lung inflammation in cystic fibrosis patients
Scientists at Children's Hospital of Pittsburgh of UPMC have identified a protein that is critical to the development of inflammation during lung infection in patients with cystic fibrosis (CF). view more (2006-11-07)
Study finds nontuberculous mycobacteria lung disease on the rise in the United States
Nontuberculous mycobacteria (NTM) are environmental organisms found in both water and soil that can cause severe pulmonary (lung) disease in humans. Pulmonary NTM is on the rise in the United States, according to a large study of people hospitalized with the condition. view more (2009-09-25)
New approach to treating cystic fibrosis lung infection shows promise
Researchers at the University of Calgary have found a new method of fighting severe lung infections in people with cystic fibrosis (CF). These findings are published in Proceedings of the National Academy of Science USA, this week. view more (2008-09-23)
UC San Diego researchers reverse pulmonary arterial hypertension in mouse models
Researchers at the University of California, San Diego, have identified a key protein that promotes the development of pulmonary arterial hypertension in humans and mice. view more (2009-10-26)
Computer simulations point to key molecular basis of cystic fibrosis
Researchers from the University of North Carolina at Chapel Hill have identified a key molecular mechanism that may account for the development of cystic fibrosis, which about 1 in 3000 children are born with in the US every year. view more (2008-03-03)
Fistula-related morbidity decreased by prompt treatment in Sierra Leone
Extent of fibrosis is the most profound factor in predicting surgical outcomes of genitourinary fistula repair, suggesting that prompt treatment could significantly improve survival. view more (2009-04-27)
Noninvasive tests for cirrhosis may help to avoid liver biopsy
Newer ultrasound and magnetic resonance (MR) imaging tests yield encouraging initial results in diagnosing fibrosis (scarring) and cirrhosis of the liver, according to three studies in the October issue of the journal Clinical Gastroenterology and Hepatology. view more (2007-10-02)
Radiologists encouraged to look beyond cancer for clinically unseen diseases
Radiologists can diagnose venous thromboembolic disease (VTED) in cancer patients earlier by looking more carefully at CT scans of the thorax, abdomen, and pelvis which are regularly done to determine the extent or stage of the cancer. view more (2007-08-15)
Pitt team first to profile genes in acutely ill idiopathic pulmonary fibrosis patients
The first findings from a one-of-a-kind, patient-driven effort to provide lung tissue for research might help doctors predict when patients with idiopathic pulmonary fibrosis (IPF) are becoming dangerously ill and also could point the way to interventions that could sustain them until life-saving transplants can be performed. view more (2009-07-07)
Common cold virus efficiently delivers corrected gene to cystic fibrosis cells
Scientists have worked for 20 years to perfect gene therapy for the treatment of cystic fibrosis, which causes the body to produce dehydrated, thicker-than-normal mucus that clogs the lungs and leads to life threatening infections. view more (2009-07-21)
Even at High Doses, Gadolinium-Based Contrast Agents Cannot by Themselves Cause Patients to Develop Nephrogenic Systemic Fibrosis
Even at very high doses, gadolinium-based contrast agents alone are not sufficient to cause nephrogenic systemic fibrosis (NSF) in patients with kidney problems. view more (2009-07-01)
Helping Cystic Fibrosis Patients Beat Bugs
People with weakened immune systems, including patients with cystic fibrosis, could be better protected in future from a highly resilient bacteria thanks to work by medical scientists from the University of Leeds. The research is presented today, Wednesday 10 September 2003, at the Society for General Microbiology's meeting at UMIST in Manchester.... view more... (2003-08-27)
Test predicts risk of liver scarring after transplant, study shows
An estimated 20 percent of people with chronic hepatitis C who receive a liver transplant will develop advanced cirrhosis, scarring of the new organ severe enough to impair its ability to function normally within five years of transplantation. view more (2005-10-06)
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