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Pulmonary Fibrosis Current Events | Pulmonary Fibrosis News | 6

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Probe position may change results in liver stiffness measurements in transient elastography
A major clinical challenge is to find the best method to evaluate and to manage the increasing numbers of patients with chronic liver disease. Liver biopsy, due to its risks and limitations, is no longer considered mandatory as the first-line indicator of liver injury, and several markers have been developed as non-invasive alternatives.   view more (2009-07-29)

A potential therapeutic agent for hepatic fibrosis
Accumulating evidence suggests that connective tissue growth factor (CCN2) plays a central role in fibrotic conditions in many organ systems.   view more (2009-08-26)

Tobacco Smoke and Alcohol Harm Liver Worse as Combo
Exposure to second-hand smoke and alcohol significantly raises the risk of liver disease, according to researchers at the University of Alabama at Birmingham (UAB).   view more (2009-02-04)

CU-Boulder technology used to identify unexpected bacteria in cystic fibrosis patients
Molecular technology developed by a University of Colorado at Boulder professor to probe extreme life forms in undersea hydrothermal vents has been used to identify unexpected bacteria strains in the lung fluid of Denver children suffering from cystic fibrosis, findings that may lead to more effective therapies.   view more (2007-12-04)

Little Evidence Behind Bronchodilator Therapy for Cystic Fibrosis
Little evidence exists to support the widespread use of bronchodilators to treat children and adults with cystic fibrosis, according to a new systematic review of published research.   view more (2005-10-26)

Newborns with respiratory distress potentially have rare genetic disease
Newborns with respiratory distress should be evaluated for primary ciliary dyskinesia, a rare genetic disease that has features similar to cystic fibrosis, says Thomas Ferkol, M.D., from Washington University School of Medicine in St. Louis.   view more (2007-02-21)

High blood pressure causes pathological scars in the heart
Fibrosis (scar tissue formation) is the determinant lesion in the subsequent evolution of the heart in a patient with high blood pressure. This item appeared in the latest edition of Nature Clinical Practice Cardiovascular Medicine, a journal that is part of the Nature group. The article published heart research recently carried out at the... view more... (2005-05-25)

NITRIC OXIDE BENEFIT FOR INFANTS UNDERGOING CONGENITAL HEART SURGERY (p 1464)
The cardiovascular problems associated with surgery for congenital heart disease in infants may be reduced with the use of postoperative nitric oxide, according to research published in this week's issue of THE LANCET. Congenital heart disease is present in five to ten per 1000 livebirths. If surgery is required, the most common defects are... view more... (2000-10-25)

Clearing the airways in cystic fibrosis
By manipulating the machinery used by our cells for quality control, researchers from the University of Pittsburgh have found a way to restore the function of cystic fibrosis (CF) airway cells.   view more (2008-08-29)

Mayo Clinic Cancer Center finds possible genetic link to pancreatic cancer
Mayo Clinic researchers have found the risk of developing pancreatic cancer at a young age (under 60) to be twice as high for people who carry a mutation of the gene that causes cystic fibrosis, compared to noncarriers.   view more (2005-10-21)

Drug Fights Cystic Fibrosis
An experimental drug that has proven effective in treating muscular dystrophy also works for cystic fibrosis, according to researchers at the University of Alabama at Birmingham (UAB).   view more (2008-02-06)

Strategy Discovered for Fighting Persistent Bacterial Infections
Researchers at National Jewish Health have discovered a promising strategy for destroying the molecular scaffolding that can make Pseudomonas bacterial infections extremely difficult to treat in cystic fibrosis patients, wearers of contact lenses, and burn victims. Jerry Nick, MD, Associate Professor of Medicine at National Jewish Health, and his... view more... (2009-03-24)

Discovery could aid fight against cystic fibrosis infection
Harvard Medical School researchers have discovered one way that a hardy disease-causing bacteria could be surviving in the lungs of chronically infected cystic fibrosis (CF) patients.   view more (2006-06-12)

Gene mutations linked to hereditary lung disease
Scientists at Johns Hopkins have identified the genetic culprits that trigger a hereditary form of a fatal lung disease. The findings, published in the March 29, 2007 issue of the New England Journal of Medicine, may provide new directions in diagnosis and treatment for families that inherit genes for the disease, as well as for those that develop... view more... (2007-03-29)

NHLBI media availability: Treatment shows long-term benefits for cystic fibrosis patients
New research suggests that inhaling hypertonic saline, a water-based concentrated salt solution, could provide long-term benefits for lung health in patients with cystic fibrosis (CF).   view more (2006-01-19)

Mucous breakthrough in mice holds promise for cystic fibrosis
A London, Canada scientist studying cystic fibrosis (CF) has successfully corrected the defect which causes the overproduction of intestinal mucous in mice.   view more (2008-07-30)

Cystic Fibrosis Foundation announces positive early results for phase 2 clinical trial of VX-770
The Cystic Fibrosis Foundation announced today that VX-770, an oral drug in development that targets a basic defect in CF, showed promising results in an ongoing Phase 2a clinical trial for patients who carry the G551D mutation of CF. The drug is being developed by Vertex Pharmaceuticals Incorporated.   view more (2008-03-28)

New Mayo Clinic MRI technology enables noninvasive liver diagnoses
Two recent Mayo Clinic studies have found that magnetic resonance elastography (MRE), a new imaging technique invented at Mayo Clinic, is an accurate tool for non-invasive diagnosis of liver diseases.   view more (2007-05-23)

Treat all patients with rare lung disease to prevent stroke, say doctors
Treatment should be offered to all people with a particular rare lung condition, regardless of whether or not they show symptoms of it, say researchers and doctors behind a new study published today.   view more (2007-11-05)

Special issue on cystic fibrosis in The Journal of Pediatrics
Cystic fibrosis is a common, fatal genetic disease in which a gene causes the body to produce abnormally thick, sticky mucus.   view more (2005-10-04)
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