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'GreeneChip' — New diagnostic tool that rapidly and accurately identifies multiple pathogens
Researchers in the Greene Infectious Disease Laboratory at Columbia University Mailman School of Public Health and their colleagues in the WHO Global Laboratory Network have developed a new tool for pathogen surveillance and discovery-the GreeneChip System. view more (2006-12-06)
Role of microRNA Identified in Thyroid Cancer
The presence of only five tiny strands of RNA is enough to clearly distinguish cancerous thyroid tissue from otherwise normal tissue, scientists say. view more (2005-12-23)
Molecule crucial for processing non-coding RNA identified
The discovery in 1977 that the coding regions of a gene could appear in separate segments along the DNA won the 1993 Nobel Prize in Physiology or Medicine for Richard J. Roberts and Phillip A. Sharp. view more (2005-10-21)
Gene therapy 'turns off' mutation linked to Parkinson's disease
A group of Northwestern University researchers is developing a novel gene therapy aimed at selectively turning off one of the genes involved in the development of Parkinson's disease. view more (2006-01-19)
Killing brain tumors from within: A 'Trojan horse' approach
A new method for targeting malignant brain tumors through inducing the cancerous cells to "commit suicide" has been developed by a team of researchers headed by a Hebrew University of Jerusalem professor of biochemistry. view more (2006-10-25)
Newly discovered gene may hold clues to evolution of human brain capacity
Scientists have discovered a gene that has undergone accelerated evolutionary change in humans and is active during a critical stage in brain development. view more (2006-08-17)
Study finds genes that 'fine-tune' muscle development process
Scientists at the University of North Carolina at Chapel Hill have found two genes that are essential for the proper development of muscle. view more (2005-12-30)
Comparing Chimp, Human DNA
Most of the big differences between human and chimpanzee DNA lie in regions that do not code for genes, according to a new study. view more (2006-10-16)
Purdue scientists treat cancer with RNA nanotechnology
Using strands of genetic material, Purdue University scientists have constructed tiny delivery vehicles that can carry anticancer therapeutic agents directly to infected cells, offering a potential wealth of new treatments for chronic diseases. view more (2005-09-14)
Flatworm genes may provide insights into human diseases, researchers say
Could vital information about many human diseases be deciphered from genes inside freshwater flatworms? A definitive yes is not the answer yet, but research at the University of Illinois at Urbana-Champaign has provided an important advance for pursuing both that idea and the biology of stem cells. view more (2005-12-14)
Small molecule interactions were central to the origin of life
In an important new paper forthcoming in the June issue of The Quarterly Review of Biology, Robert Shapiro (New York University) argues against the widely held theory that the origin of life began with the spontaneous appearance of a large, replicating molecule such as RNA. view more (2006-05-17)
When it comes to gene transcription, random pauses aren't quite so random, study finds
Of the thousands of proteins produced in our cells, few are as important as the enzyme RNA polymerase (RNAP), which has the unique ability to faithfully copy genetic information from DNA. view more (2006-06-16)
Accelerated evolution converts RNA enzyme to DNA enzyme in vitro
This 'evolutionary conversion' provides a modern-day snapshot of how life as we understand it may have first evolved out of the earliest primordial mix of RNA-like molecules-sometimes referred to as the "pre-RNA world"-into a more complex form of RNA-based life (or the "RNA world") and eventually to cellular life based on DNA... view more... (2006-03-28)
MicroRNA tweaks protein that controls early heart development
Researchers at UT Southwestern Medical Center have discovered how a small molecule of RNA called microRNA - a chemical cousin of DNA - helps fine tune the production of a key protein involved in the early development of heart muscle. view more (2005-06-13)
Study finds protein is required for human chromosome production
Scientists at the University of North Carolina at Chapel Hill School of Medicine have identified an elusive protein that performs a necessary step in the production of human chromosomes. view more (2005-10-13)
Rehydrate - your RNA needs it
Water, that molecule-of-all-trades, is famous for its roles in shaping the Earth, sustaining living creatures and serving as a universal solvent. view more (2006-08-23)
Infection-fighting protein could be key to autoimmune disease, say U-M scientists
Scientists at the University of Michigan Medical School have discovered that a protein called cryopyrin responds to invading bacteria by triggering the activation of a powerful inflammatory molecule called IL-1beta, which signals the immune system to attack pathogens and induces fever to protect the body against infection. view more (2006-01-12)
Genetically engineered mosquitoes show resistance to dengue fever virus
Researchers have successfully created a genetically engineered mosquito that shows a high level of resistance against the most prevalent type of dengue fever virus, providing a powerful weapon against a disease that infects 50 million people each year. view more (2006-03-09)
Genome circularization and RNA virus replication
As featured on the cover of the August 15th issue of G&D, an Argentinian research team, led by Dr. Andrea Gamarnik, report on their recent discovery of a novel mechanism of dengue virus replication. view more (2006-08-01)
Micro-molecule plays big role in birth defects
University of Florida researchers have learned how to selectively shut down a flyweight-sized genetic molecule that packs a heavyweight punch, a discovery that may help doctors better understand cancer, birth defects and other health problems. view more (2005-07-20)
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