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New plant study reveals a 'deeply hidden' layer of the transcriptome
Cells keep a close watch over the transcriptome - the totality of all parts of the genome that are expressed in any given cell at any given time. view more (2007-12-28)
Newly described 'dragon' protein could be key to bird flu cure
Scientists and researchers have taken a big step closer to a cure for the most common strain of avian influenza, or "bird flu," the potential pandemic that has claimed more than 200 lives and infected nearly 400 people in 14 countries since it was identified in 2003. view more (2008-07-16)
Baumann lab identifies elusive telomere RNA subunit in single cell model
The Stowers Institute's Baumann Lab has identified the long-sought telomerase RNA gene in a single-cell research model. Their findings have been posted to the Web site of the journal Nature Structural & Molecular Biology and will appear in a future print edition. view more (2007-12-28)
RNA interference therapy heals growth deficiency disorder in a live animal
A team of Vanderbilt researchers have demonstrated for the first time that a new type of gene therapy, called RNA interference, can heal a genetic disorder in a live animal. view more (2007-12-19)
New pathway provides more clues about BRCA1 role in breast cancer
A breast cancer gene's newly discovered role in repairing damaged DNA may help explain why women who inherit a mutated copy of the gene are at increased risk for developing both breast and ovarian cancer. view more (2008-01-16)
Scientists discover possible new treatment for genetic diseases
Scientists from Imperial College London, the University of Leicester, and Hammersmith Hospital have found a way to stop certain types of genetic diseases from occurring by modifying the way DNA is turned into proteins. The research published in this month's Proceedings of the National Academy of Science shows how the researchers have been able to... view more... (2003-03-14)
Protein 'tubules' free avian flu virus from immune recognition
A protein found in the virulent avian influenza virus strain called H5N1 forms tiny tubules in which it "hides" the pieces of double-stranded RNA formed during viral infection, which otherwise would prompt an antiviral immune response from infected cells, said Baylor College of Medicine researchers in an online report in the journal... view more... (2008-11-06)
Novel 'on-off switch' mechanism stops cancer in its tracks
A tiny bit of genetic material with no previously known function may hold the key to stopping the spread of cancer, researchers at Yale School of Medicine and Sichuan University in Chengdu, China report in two papers in the September 7-11 issue of Proceedings of the National Academy of Sciences. view more (2009-09-24)
Pol3 mutation disrupts organ growth
The cellular mechanism that turns DNA into all of the thousands of proteins that make up a human body is itself both intricate and interesting. view more (2007-11-27)
MicroRNA works with Ago2 protein to regulate blood cell development
MicroRNAs became the stars of the RNA universe when, in 2001, scientists found that these short RNAs can control whether or not genes are expressed. view more (2007-07-27)
Mechanism for the in-vivo transport of siRNA
It all started with flowers: in the nineties of the last century Norwegian researchers discovered that additional copies of a particular gene in petunias inhibited its activity instead of reinforcing it as had been assumed. view more (2007-09-18)
Candidate genes found which may play a role in cancer progressing from non-invasive to invasive
Scientists in America have made the first steps in identifying a group of genes which may be involved in the progression of breast cancer from non-invasive to invasive, the 3rd European Breast Cancer Conference in Barcelona heard today (Thursday 21 March). view more (2002-03-19)
Earth's original ancestor was LUCA, not Adam nor Eve
Here's another argument against intelligent design. An evolutionary geneticist from the Université de Montréal, together with researchers from the French cities of Lyon and Montpellier, have published a ground-breaking study that characterizes the common ancestor of all life on earth, LUCA (Last Universal Common Ancestor). view more (2008-12-18)
Europe develops new technologies to boost health of livestock
A range of new technologies including genetic modification (GM) and RNA Interference are being deployed to improve the health of farm animals in a series of European and global initiatives. The ground was laid for a European platform to develop new treatments that exploit these technologies at a recent workshop organised by the European Science... view more... (2008-04-09)
Bits of 'junk' RNA aid master tumor-suppressor gene
Little-known bits of RNA help master tumor-suppressor gene do its job, U-M cancer researchers find. Three micro RNA genes appear to be key partners of protective gene p53; their loss is linked to common type of lung cancer. view more (2007-08-24)
Diabetes linked to male infertility; excess sugars in the body have direct effect on sperm quality
Diabetes in men has a direct effect on fertility, a scientist told the 24th annual conference of the European Society of Human Reproduction and Embryology today. view more (2008-07-09)
Decline in blood platelet count associated with increased risk of HIV-related dementia
HIV patients with declining platelet counts appear to be at increased risk for HIV-associated dementia, according to a report in the September issue of Archives of Neurology, one of the JAMA/Archives journals. view more (2007-09-11)
Study Suggests Potential Of Low-cost Options For Monitoring Disease Status In Hiv-1-Infected Children In Less-developed Countries (pp 1597, 1625)
Authors of a research letter in this week's issue of THE LANCET highlight how assessment of total blood lymphocyte count and albumen concentrations could have potential as low-cost alternatives in assessing the disease status of HIV-1-infected children in less-developed countries. The cost of laboratory analysis of CD4 lymphocyte count and... view more... (2003-11-12)
Plant polymerases IV and V are special forms of Polymerase II
It's a little like finding out that Superman is actually Clark Kent. A team of biologists at Washington University in St. Louis has discovered that two vital cellular components, nuclear RNA Polymerases IV and V (Pol IV and V), found only in plants, are actually specialized forms of RNA Polymerase II, an essential enzyme of all eukaryotic... view more... (2009-01-07)
Getting wise to the influenza virus' tricks
Influenza is currently a grave concern for governments and health organisations around the world. The worry is the potential for highly virulent bird flu strains, such as H5N1, to develop the ability to infect humans easily. New drugs and vaccines to halt the spread of the virus are badly needed. view more (2008-05-05)
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