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Scripps Research Scientists Discover Remarkable Editing System For Protein Production
Even small mistakes made by cells during protein production can have profound disease effects, but the processes cells use to correct mistakes have been challenging to decipher. Recent work by scientists at The Scripps Research Institute, however, has uncovered two surprising new methods for such editing. view more (2008-01-03)
Genetic pathway critical to disease, aging found
The same chemical reaction that causes iron to rust plays a similarly corrosive role in our bodies. Oxidative stress chips away at healthy cells and is a process, scientists know, that contributes to a host of diseases and conditions in humans ranging from Alzheimer's, heart disease and stroke to cancer and the inexorable process of aging. view more (2008-02-21)
Brain tissue reveals possible genetic trigger for schizophrenia
A study led by scientists from the University of North Carolina at Chapel Hill may have identified a molecular mechanism involved in the development of schizophrenia. view more (2007-03-29)
Evolution in action: Our antibodies take 'evolutionary leaps' to fight microbes
With cold and flu season in full swing, the fact that viruses and bacteria rapidly evolve is apparent with every sneeze, sniffle, and cough. A new report in the January 2009 issue of The FASEB Journal, explains for the first time how humans keep up with microbes by rearranging the genes that make antibodies to foreign invaders. This research fills... view more... (2009-01-06)
Researchers identify and shut down protein that fuels ovarian cancer
A protein that stimulates blood vessel growth worsens ovarian cancer, but its production can be stifled by a tiny bit of RNA wrapped in a fatty nanoparticle, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the Journal of the National Cancer Institute. view more (2008-02-27)
New Genetic Mechanism For Evolution
A team of researchers from the Universitat Autònoma de Barcelona (UAB) has discovered that transposons, small DNA sequences that travel through the genomes, can silence the genes adjacent to them by inducing a molecule called antisense RNA. This is a new mechanism for evolution that has been unknown until now. The research has been recently... view more... (2004-07-16)
European researchers tackle mitosis
Scientists at the European Molecular Biology Laboratory (EMBL) join forces with top scientists from eleven research institutes in Austria, Germany, Italy, France and the United Kingdom for "MitoCheck" - the largest integrated research project on cell cycle control within the European Commission's 6th Framework Programme (FP6). The... view more... (2004-07-15)
The cooperative view: New evidence suggests a symbiogenetic origin for the centrosome
There are two ways in which cooperation is the theme of a paper published this week by Mark Alliegro and Mary Anne Alliegro, scientists at the Marine Biological Laboratory's (MBL) Josephine Bay Paul Center. view more (2008-05-07)
Blocking the spread of antibiotic resistance in bacteria
It's as simple as A, T, G, C. Northwestern University scientists have exploited the Watson-Crick base pairing of DNA to provide a defensive tool that could be used to fight the spread of antibiotic resistance in bacteria -- one of the world's most pressing public health problems. view more (2008-12-19)
Scientists find missing evolutionary link using tiny fungus crystal
The crystal structure of a molecule from a primitive fungus has served as a time machine to show researchers more about the evolution of life from the simple to the complex. view more (2008-01-03)
Scientists Identify Key Roadblock to Gene Expression
A team of scientists has provided, for the first time, a detailed map of how the building blocks of chromosomes, the cellular structures that contain genes, are organized in the fruit fly Drosophila melanogaster. view more (2008-05-09)
Mechanisms of cardiovascular disease and cancer give clues to new therapies
Cardiovascular conditions leading to heart attacks and strokes are treated quite separately from common cancers of the prostate, breast or lung, but now turn out to involve some of the same critical mechanisms at the molecular level. view more (2008-11-24)
A new key to detecting deadly aortic aneurysms
Yale scientists have discovered a way to use a simple blood test that may accurately detect thoracic aneurysm disease (TAA), which gives little warning and is almost always fatal if untreated. view more (2007-10-25)
UK physician revolutionizes gene research
A dramatic new study published in the most recent issue of Nature questions some of the mechanisms underlying a new class of drugs based on Nobel Prize-winning work designed to fight diseases ranging from macular degeneration to diabetes. view more (2008-03-27)
Abnormal glutamine repeats interfere with key transcription factor, leading to neurodegeneration
Although repeating sequences of three nucleotides encoding some of the bodies' 20 amino acids are a normal part of protein composition, abnormal expansion of trinucleotide repeats is the known cause of multiple inherited neurodegenerative disorders, including Huntington disease. view more (2007-11-14)
Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA
Scientists have discovered a key protein in the toxic brain pathway that leads to fragile X tremor/ataxia syndrome (FXTAS), an inherited neurodegenerative disorder. view more (2007-08-16)
UVA Reports Surprising Findings Related to Heart Protein, NKX2-5,
New research from the University of Virginia Health System shows that, in cases of Type 1 myotonic muscular dystrophy (DM1), a well known heart protein does several surprising things. DM1 is the most common form of muscular dystrophy in adults and affects approximately 40,000 adults and children in the U.S. view more (2007-12-18)
Prediction of RNA pseudoknots using heuristic modeling with mapping and sequential folding
An algorithm utilizing structure mapping and thermodynamics is introduced for RNA pseudoknot prediction. The method finds the minimum free energy in the context of the biological folding direction (5' to 3') of RNA sequences. view more (2007-09-19)
New insights into how the oncogenic protein c-Myc regulates cell growth
New findings by Swedish and German scientists on the regulation of cellular growth are published in the March issue of Nature Cell Biology. view more (2005-02-20)
Symposium marks 30th anniversary of discovery of third domain of life
Thirty years ago this month, researchers at the University of Illinois published a discovery that challenged basic assumptions about the broadest classifications of life. view more (2007-10-17)
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