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MicroRNAs play a big part in gene regulation-and evolution
egulating when and where certain proteins are made is crucial to the normal functioning of living things. To make proteins, information from DNA is transcribed into RNA molecules and then translated into the amino acids building blocks of proteins. view more (2005-06-24)
HIV inserts into human genome using a DNA-associated protein
A human DNA-associated protein called LEDGF is the first such molecule found to control the location of HIV integration in human cells. view more (2005-11-28)
Brain gene shows dramatic difference from chimp to human
One of the fastest-evolving pieces of DNA in the human genome is a gene linked to brain development. view more (2006-08-17)
University of Iowa scientists explore function of 'junk DNA'
University of Iowa scientists have made a discovery that broadens understanding of a rapidly developing area of biology known as functional genomics and sheds more light on the mysterious, so-called "junk DNA" that makes up the majority of the human genome. view more (2006-11-14)
Microbiology Today: Discovering the secrets of extraordinary life forms
Not long ago, the discovery of viruses revolutionized our thinking about the lower limits of microscopic life. Now even small strands of RNA are found to be infectious in plants, and proteins are believed to cross the species barrier and cause brain disease. In the November 2000 issue of Microbiology Today Nicola Spence and Dez Barbara of... view more... (2000-11-13)
NYU chemists create 'nanorobotic' arm to operate within DNA sequence
New York University chemistry professor Nadrian C. Seeman and his graduate student Baoquan Ding have developed a DNA cassette through which a nanomechanical device can be inserted and function within a DNA array, allowing for the motion of a nanorobotic arm. view more (2006-12-08)
Coding for arthropods-what's so special about insects and spiders?
The central dogma of molecular biology is that DNA makes RNA makes protein. This relies on a specific underlying code which relates given triplets of RNA nucleotides into specific amino acids. view more (2006-04-25)
New telomere discovery could help explain why cancer cells never stop dividing
A group working at the Swiss Institute for Experimental Cancer Research (ISREC) in collaboration with the University of Pavia has discovered that telomeres, the repeated DNA-protein complexes at the end of chromosomes that progressively shorten every time a cell divides, also contain RNA. view more (2007-10-05)
Non-coding RNAs help silence the mammalian transcription
Dr. Shirley Tilghman and colleagues (Princeton University) lend new insight into the mechanism of genomic imprinting, demonstrating a necessary role for a non-coding RNA transcript in the silencing of an imprinted gene cluster in mice. view more (2006-05-15)
Remote control for human growth hormone gene expression
Researchers at the University of Pennsylvania School of Medicine recently discovered a novel mechanism that works over an extensive genomic distance and controls the expression of human growth hormone (hGH) in the pituitary gland. view more (2006-08-14)
UW scientists unravel critical genetic puzzle for flu virus replication
Like any other organism, an influenza virus's success in life is measured by its genetic track record, its ability to pass on genes from one generation to the next. view more (2006-01-26)
'Pregnant' protein-coding genes carry RNA 'babies'
Scientists from the Chinese Academy of Sciences have performed a comprehensive analysis of small, non-protein-coding RNAs in the model nematode, C. elegans. view more (2006-01-10)
MicroRNA may have fail-safe role in limb development
A tiny strand of molecules plays a role in how our arms and legs develop and grow-a finding that sheds light on perplexing bits of material once dismissed as genetic "junk," say scientists at the University of Florida and Harvard University. view more (2005-12-02)
Hepatitis C complicated by morphine withdrawal
Researchers at the University of Pennsylvania have demonstrated that morphine withdrawal complicates hepatitis C by suppressing IFN-alpha-mediated immunity and enhancing virus replication. view more (2005-10-31)
Researchers find protein that silences genes
A team of researchers, including biologists at Washington University in St. Louis, has discovered the key role one protein plays in a major turn-off - in this case, the turning off of thousands of nearly identical genes in a hybrid plant. view more (2006-05-08)
A real time look at interactions between RNA and proteins
For the first time, researchers can now peer inside intact cells to not only identify RNA-binding proteins, but also observe-in real-time-the intricate activities of these special molecules that make them key players in managing some of the cell's most basic functions. view more (2006-01-30)
New study expands understanding of the role of RNA editing in gene control
For many years, scientists thought gene activity was relatively straightforward: Genes were transcribed into messenger RNA, which was processed and translated into the proteins of the body. view more (2005-12-27)
How purple corn and RNA break genetic laws
A newly cloned gene in corn will help explain how unusual interactions between a parent's genes can have lasting effects in future generations. The finding has implications for breeding better crop plants and unraveling complex genetic diseases. view more (2006-07-20)
New and sharper X-rays of cell's ribosome could lead to better antibiotics
A new, sharper picture of the nano-machine that translates our genetic program into proteins promises to help researchers explain how some types of antibiotics work and could lead to the design of better ones. view more (2005-11-04)
Life's origins were easier than was thought
In the primordial soup that produced life on earth, there were organic molecules that combined to produce the first nucleic acid chains, which were the first elements able to self-replicate. view more (2005-09-16)
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