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Solexa and collaborating scientists illuminate the small RNA component of the transcriptome
Solexa, Inc. (Nasdaq: SLXA) today announced that its researchers in collaboration with the Delaware Biotechnology Institute and the University of Delaware reported the most comprehensive analysis to date of the small RNA component of the transcriptome. view more (2005-09-07)
New protein vital for immune response is found
A newly discovered protein not only is vital to the immune system's ability to fight off viral infections but also has been found in an unexpected location within the cell, causing researchers to rethink previous notions about the workings of the human immune system. view more (2005-08-26)
Structure of viral harpoon protein reveals how viruses enter cells
A team of Northwestern University researchers has solved the structure of a molecule that controls the ability of viruses of the paramyxovirus family, including the viruses that cause measles, mumps, and many human respiratory diseases, to fuse with and infect human cells. view more (2006-01-05)
Yale study explains complex infection fighting mechanism
Yale School of Medicine researchers report in Nature Immunology how infection fighting mechanisms in the body can distinguish between a virus and the healthy body, shedding new light on auto immune disorders. view more (2006-01-11)
Tool developed to silence genes in specific tissues using RNAi
Researchers at The University of Texas M. D. Anderson Cancer Center say they have jumped a significant hurdle in the use of RNA interference (RNAi), believed by many to be the ultimate tool to both decode the function of individual genes in the human genome and to treat disease. view more (2006-01-17)
UCLA researchers unravel a mystery about DNA
UCLA researchers in collaboration with researchers at Rutgers University have solved longstanding mysteries surrounding DNA transcription, the first step in carrying out instructions contained in our genes. view more (2006-11-17)
Transcription factor protein's role in cell death, neurodegeneration and schizophrenia
Researchers at the University of Pennsylvania School of Medicine discovered that a protein called Elk-1 interacts with mitochondria, the energy storehouse of a cell, suggesting that this protein -— typically active in the nucleus — could play a role in cell death and mitochondria-related diseases such as neurodegeneration and... view more... (2006-06-08)
Molecular steps involved in the creation of gene-silencing MicroRNAs identified
First discovered only a few brief years ago, microRNAs are small, remarkably powerful molecules that appear to play a pivotal role in gene silencing, one of the body's main strategies for regulating its genome. A scant 22 nucleotides in length, miRNAs appear to work by binding to and somehow interfering with messenger RNA, itself responsible for... view more... (2005-06-23)
RNAi and telomere length
A team of Russian scientists, led by Dr. Vladimir Gvozdev (Russian Academy of Sciences) reports on a novel link between RNAi and telomere maintenance in the Drosophila germline. view more (2006-02-01)
Protein splicing upsets the DNA colinearity paradigm
Understanding medical research problems often relies on the direct, linear relationship between the sequence of a protein and the DNA encoding that protein. view more (2006-09-08)
A new step towards an AIDS vaccine
Progressive disease after HIV infection is inversely correlated with the presence of plasmacytoid dendritic cells (pDCs), a subset of the dendritic cell family and the major producers of type 1 interferon in the body. view more (2005-10-14)
Interfering RNA silences genes in 'slippery' immune cells
A technical advance in laboratory techniques may provide biology researchers broader access to RNA interference, a process of blocking the activity of targeted genes. view more (2006-05-09)
New gene regulation mechanism discovered
Researchers at Cold Spring Harbor Laboratory have discovered a new kind of messenger RNA molecule that is converted from non-protein coding status to protein coding status in response to cellular stress such as viral infection. view more (2005-10-21)
LSUHSC research finds evidence of RNA in structures essential to cell division
Research led by Mark Alliegro, PhD, Professor of Cell Biology and Anatomy at Louisiana State University Health Sciences Center at New Orleans, provides evidence for the first time that centrosomes, which play a key role in cell division, may carry their own genetic machinery, answering a controversial question of long standing. view more (2006-06-14)
Renegade RNA — Clues to cancer and normal growth
Researchers at Johns Hopkins have discovered that a tiny piece of genetic code apparently goes where no bit of it has gone before, and it gets there under its own internal code. view more (2007-01-05)
DNA constraints control structure of attached macromolecules
A new method for manipulating macromolecules has been developed by researchers at the University of Illinois at Urbana-Champaign. The technique uses double-stranded DNA to direct the behavior of other molecules. view more (2005-06-29)
Neurons find their place in the developing nervous system with the help of a sticky molecule
The brain, that exquisite network of billions of communicating cells, starts to take form with the genesis of nerve cells. Most newborn nerve cells, also called neurons, must travel from their birthplace to the position they will occupy in the adult brain. view more (2006-04-26)
Researchers find 'secret weapon' used by SARS virus
In 2003, the highly contagious and often-deadly mystery disease now called SARS emerged explosively out of Southern China. It eventually killed an estimated 916 people in Asia, Europe, and North and South America-nearly one in ten of those it infected. view more (2006-08-08)
Detection of Salmonella in 24 hours
The food and drink we consume have to pass strict quality controls. Nevertheless, these measures are not always sufficient, given that sometimes certain foodstuffs can still give rise to food poisoning, most often caused by micro-organisms. view more (2007-02-09)
Twin molecular scissors link creation of microRNAs with gene-silencing
One of the body's primary strategies for regulating its genome is a kind of targeted gene silencing orchestrated by small molecules called microRNAs, or miRNAs. view more (2005-11-04)
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