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Carnegie Mellon University research reveals how cells process large genes
Important messages require accurate transmission. Big genes are especially challenging because they combine many coding segments (exons) that lie between long stretches of non-coding elements (introns). view more (2005-08-24)
Toxic molecule may cause most common type of muscular dystrophy
Doctors at the University of Virginia Health System have shown for the first time that getting rid of poisonous RNA (ribonucleic acid) in muscle cells can reverse myotonic dystrophy, the most common type of muscular dystrophy in adults. view more (2006-08-25)
Tiny molecule controls stress-induced heart disease
A tiny snippet of RNA, a chemical cousin of DNA, controls damage to the heart under several types of stress, researchers at UT Southwestern Medical Center have found. view more (2007-03-23)
MicroRNA helps prevent tumors
A microRNA directly regulates a gene implicated in human cancers, researchers from Whitehead Institute and Massachusetts Institute of Technology report in the February 22nd online issue of Science. view more (2007-02-23)
Flu can bide time in icy limbo before re-emerging
It sounds like a campy '50s horror movie ("It Came from the Ice!"), but a Bowling Green State University biologist believes it's a very real possibility. Dr. Scott Rogers is talking about the potential for long-dormant strains of influenza, packed in ice in remote global outposts, to be unleashed by melting and migratory birds. view more (2006-11-29)
Gladstone investigators identify a new protective action for the powerful anti-HIV factor, APOBEC3G
Scientists at the Gladstone Institute of Virology and Immunology (GIVI) have identified a previously unknown function of APOBEC3G (A3G), a protein that acts against HIV, a finding that may lead to new approaches for controlling HIV infection. view more (2006-10-03)
Phoenix rising: Scientists resuscitate a 5 million-year-old retrovirus
A team of scientists has reconstructed the DNA sequence of a 5-million-year-old retrovirus and shown that it is able to produce infectious particles. view more (2006-10-31)
Pair of microRNA molecules controls major oncogene in most common leukemia
Researchers at Ohio State University have discovered that two microRNA (miRNA) molecules help control the oncogene responsible for a dangerous form of B-cell chronic lymphocytic leukemia (B-CLL), the most common human leukemia in the world. view more (2006-12-18)
Molecular markers signal early metastases from ocular melanoma
Patients with melanoma of the eye are at risk for liver metastases, which are often not detected until they have turned into large, lethal tumors. view more (2006-09-14)
From a lowly yeast, researchers divine a clue to human disease
Working with a common form of brewer's yeast, University of Wisconsin-Madison researchers have uncovered novel functions of a key protein that allow it to act as a master regulatory switch - a control that determines gene activity and that, when malfunctioning in humans, may contribute to serious neurological disorders. view more (2006-12-08)
NYU researchers developing molecular delivery vehicles for genetic therapies
Researchers at New York University are working to develop molecular delivery vehicles that can be used to transport nucleic acids into diverse cell types, which may lead to eventual applications in genetic therapies. view more (2006-11-14)
Nanotech tools yield DNA transcription breakthrough
Rutgers researcher Richard H. Ebright and his collaborators have resolved key questions regarding transcription, the fundamental life process that was the subject of the 2006 Nobel Prize in Chemistry. view more (2006-11-17)
MBL Scientists Find Evidence of RNA in Organelle Essential to Cell Division
Despite more than a century of study, scientists know relatively little about the inner workings of centrosomes—organelles essential to cell division in humans and animals. view more (2006-06-07)
Blood cells linked to heart attacks, other inflammatory diseases
Two human blood cells that help fight blood loss, infection, and inflammation are responsible as well for starting a series of molecular events that results in overproduction of Cox-2, an enzyme involved in heart attack, stroke, atherosclerosis, and other inflammatory diseases. view more (2006-10-09)
Nanotechnology innovation may revolutionize gene detection in a single cell
Scientists at Arizona State University's Biodesign Institute have developed the world's first gene detection platform made up entirely from self-assembled DNA nanostructures. view more (2008-01-11)
RNA found in the cellular centrosome of surf clams
Researchers at Rensselaer Polytechnic Institute, the Marine Biological Laboratory (MBL) in Woods Hole and Louisiana State University (LSU) Health Sciences Center have discovered the presence of the genetic material RNA in the centrosome, the organizing structure inside each cell that assures proper cell division. view more (2006-06-07)
Blocking Cancer-Causing Gene Improves Radiation Effectiveness, Jefferson Researchers Find
Inhibiting a particular cancer-causing gene can enhance the cell-killing effects of radiation, a team of radiation oncologists and cancer biologists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have found. view more (2006-11-09)
Killing the messenger RNA — But which one?
Tiny molecules called microRNAs, only 19 to 21 nucleotides in length, are able to effectively silence sometimes large sets of genes. They do this by specifically binding to and neutralizing another form of RNA called messenger RNA, responsible for conveying the information from genes to the cellular machinery that uses that information to create... view more... (2007-02-23)
Molecular imaging may lead to earlier diagnosis of childhood respiratory virus
Scientists have used a powerful molecular imaging technique to see inside living cells infected with the most pervasive and potentially fatal childhood respiratory virus known to medicine - respiratory syncytial virus (RSV). view more (2006-04-19)
Scientists use saliva's 'diagnostic alphabets' to diagnose disease
Today, during the 85th General Session of the International Association for Dental Research, scientists are reporting that the use of saliva for clinical detection of major human diseases is only a few years away. view more (2007-03-22)
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