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Enzyme alerts cell's powerful army to repair DNA damage
Scientists know that inside each cell, a little engine called RNA polymerase II does one essential job: It copies instructions from genes in the nucleus that get carried to production units in the rest of the cell to support our daily needs. view more (2007-09-06)
Scientists find new agent to fight genetic disorders -- Zorro-Locked Nucleic Acid
A study to appear in the June 2007 issue of The FASEB Journal describes a new agent, called "Zorro-LNA," which has the potential to stop genetic disorders in their tracks. view more (2007-04-30)
Scripps Florida scientists develop a process to disrupt hepatitis C virion production
HCV is a significant human pathogen, infecting more than three percent of the world's population. The incidence of infection in the United States has been estimated to be as high as 4 million cases. view more (2008-03-24)
Human genetic 'deserts' are teeming with significant life
Many of the areas of the human genome previously thought to be deserts are in fact teeming with life, a scientist will tell the annual conference of the European Society of Human Genetics. view more (2007-06-19)
Boston Univeristy bioengineers devise 'dimmer swith' to regulate gene expression in mammal cells
Three Boston University biomedical engineers have created a genetic dimmer switch that can be used to turn on, shut off, or partially activate a gene's function. view more (2007-07-27)
Gene profiling predicts resistance to breast cancer drug Herceptin
Using gene chips to profile tumors before treatment, researchers at Harvard and Yale Universities found markers that identified breast cancer subtypes resistant to Herceptin, the primary treatment for HER2-positive breast cancer. view more (2007-02-21)
Scientists confirm that parts of earliest genetic material may have come from the stars
Scientists have confirmed for the first time that an important component of early genetic material which has been found in meteorite fragments is extraterrestrial in origin, in a paper published on 15 June 2008. view more (2008-06-16)
Born under the sun: UV light and the origin of life
Early evolution of life as we know it may have depended on DNA's ability to absorb UV light. This insight into the early moments of life on Earth comes from research published today in the journal BMC Evolutionary Biology. The research fills in one of the major gaps in our understanding about the origins of life: how single molecules were able to... view more... (2003-05-27)
Small molecules may explain psoriasis
A research team at the Swedish medical university Karolinska Institutet has shown for the time that microRNA, small RNA molecules, may play an important role in the development of inflammatory skin diseases such as psoriasis and atopic eczema. view more (2007-07-12)
A new control mechanism for genetic code translation discovered in bacteria
Almost all organisms, from bacteria to human beings, share the same genetic code, a group of universal instructions used to convert DNA or RNA sequences into proteins, the "building blocks" of life. view more (2008-02-15)
RNA-associated introns guide nerve-cell channel production
Researchers at the University of Pennsylvania School of Medicine have discovered that introns, or junk DNA to some, associated with RNA are an important molecular guide to making nerve-cell electrical channels. view more (2008-02-06)
Small RNAs can prevent spread of breast cancer
Howard Hughes Medical Institute researchers have identified small pieces of ribonucleic acid (RNA) that suppress the spread of breast cancer to the lungs and bone. The new research shows that the most invasive and aggressive human breast cancer tumors are missing three critical microRNA molecules. view more (2008-01-10)
Plant viruses from past provide ecological clues
Taking the medical history of a grassland may seem a bit esoteric - after all, how sick can grass be? However, scientists have discovered plant viruses from as early as 1917 containing information crucial not only for plant scientists, but for those in ecology, human health and bioterrorism. view more (2007-10-09)
RNA splicing factor implicated in ovarian tumor cell growth
An RNA-binding protein that is overproduced in ovarian cancer may present a new target for diagnosis or treatment of ovarian and other cancers, according to researchers at the University of Illinois at Chicago. view more (2007-04-10)
MGH researchers describe new way to identify, evolve novel enzymes
The intricate interplay of proteins and other chemicals that underlies most biological activities requires the participation of enzymes, specialized molecules that accelerate chemical reactions between molecules. view more (2007-08-16)
Hungry microbes share out the carbon in the roots of plants
Sugars made by plants are rapidly used by microbes living in their roots, according to new research at the University of York, creating a short cut in the carbon cycle that is vital to life on earth. view more (2007-10-19)
Scripps research scientists find key culprits in lupus
The more than 1.5 million Americans with systemic lupus erythematosus (or lupus) suffer from a variety of symptoms that flare and subside, often including painful or swollen joints, extreme fatigue, skin rashes, fever, and kidney problems. view more (2009-06-30)
Clearance of hepatitis C viral infection after liver transplantation
Touching stories of living donor transplantation are continuously happening in hospitals. One of these stories is reported recently in the August 14 issue of the World Journal of Gastroenterology because of its shining significance in hepatology. view more (2007-08-29)
Protein binds whenever it can
Dutch cancer researcher Joost Martens has discovered that the protein p300, which plays an important role in the correct transcription of DNA to RNA, can bind to DNA at several sites. The protein can also occupy a position in various complexes, each with its own protein composition. This knowledge is important for gaining a better understanding of... view more... (2003-06-24)
Study of protein folds offers insight into metabolic evolution
Researchers at the University of Illinois have constructed the first global family tree of metabolic protein architecture. Their approach offers a new window on the evolutionary history of metabolism. view more (2007-05-21)
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