RNA Enzyme Current Events | RNA Enzyme News
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Protein binds whenever it can
Dutch cancer researcher Joost Martens has discovered that the protein p300, which plays an important role in the correct transcription of DNA to RNA, can bind to DNA at several sites. The protein can also occupy a position in various complexes, each with its own protein composition. This knowledge is important for gaining a better understanding of... view more... (2003-06-24)
New Piece Found in the Puzzle of Epigenetics
A team of scientists led by Professor Dirk Eick of Helmholtz Zentrum München has identified the enzyme TFIIH kinase as an important factor in the epigenetic regulation of the cell nucleus enzyme RNA polymerase II. view more (2009-06-17)
Researchers discover RNA repair system in bacteria
In new papers appearing this month in Science and the Proceedings of the National Academy of Sciences, University of Illinois biochemistry professor Raven H. Huang and his colleagues describe the first RNA repair system to be discovered in bacteria. view more (2009-10-13)
Accelerated evolution converts RNA enzyme to DNA enzyme in vitro
This 'evolutionary conversion' provides a modern-day snapshot of how life as we understand it may have first evolved out of the earliest primordial mix of RNA-like molecules-sometimes referred to as the "pre-RNA world"-into a more complex form of RNA-based life (or the "RNA world") and eventually to cellular life based on DNA... view more... (2006-03-28)
Pol3 mutation disrupts organ growth
The cellular mechanism that turns DNA into all of the thousands of proteins that make up a human body is itself both intricate and interesting. view more (2007-11-27)
A brave new "old world" of RNA
A new function for RNA, which further elucidates how genes are expressed and regulated, is described on the 25th of November issue of the journal Nature. view more (2004-11-22)
Baumann lab identifies elusive telomere RNA subunit in single cell model
The Stowers Institute's Baumann Lab has identified the long-sought telomerase RNA gene in a single-cell research model. Their findings have been posted to the Web site of the journal Nature Structural & Molecular Biology and will appear in a future print edition. view more (2007-12-28)
New telomere discovery could help explain why cancer cells never stop dividing
A group working at the Swiss Institute for Experimental Cancer Research (ISREC) in collaboration with the University of Pavia has discovered that telomeres, the repeated DNA-protein complexes at the end of chromosomes that progressively shorten every time a cell divides, also contain RNA. view more (2007-10-05)
New compound effectively treats fungal infections
A new mechanism to attack hard-to-treat fungal infections has been revealed by scientists from the biotech company Anacor Pharmaceuticals Inc., California, and the European Molecular Biology Laboratory [EMBL] outstation in Grenoble, France. view more (2007-06-25)
MGH researchers describe new way to identify, evolve novel enzymes
The intricate interplay of proteins and other chemicals that underlies most biological activities requires the participation of enzymes, specialized molecules that accelerate chemical reactions between molecules. view more (2007-08-16)
Link uncovered between viral RNA and human immune response
In its fight against an intruding virus, an enzyme in our immune system may sense certain types of viral RNA pairs, according to scientists. view more (2009-08-05)
Prediction of RNA pseudoknots using heuristic modeling with mapping and sequential folding
An algorithm utilizing structure mapping and thermodynamics is introduced for RNA pseudoknot prediction. The method finds the minimum free energy in the context of the biological folding direction (5' to 3') of RNA sequences. view more (2007-09-19)
Genome circularization and RNA virus replication
As featured on the cover of the August 15th issue of G&D, an Argentinian research team, led by Dr. Andrea Gamarnik, report on their recent discovery of a novel mechanism of dengue virus replication. view more (2006-08-01)
A new control mechanism for genetic code translation discovered in bacteria
Almost all organisms, from bacteria to human beings, share the same genetic code, a group of universal instructions used to convert DNA or RNA sequences into proteins, the "building blocks" of life. view more (2008-02-15)
New tool isolates RNA within specific cells
A team of University of Oregon biologists, using fruit flies, has created a way to isolate RNA from specific cells, opening a new window on how gene expression drives normal development and disease-causing breakdowns. view more (2009-05-18)
Body's anti-HIV drug explained
Humans have a built-in weapon against HIV, but until recently no one knew how to unlock its potential. view more (2008-10-13)
Scripps scientists develop first examples of RNA that replicates itself indefinitely
Findings could inform biochemical questions about how life began. Now, a pair of Scripps Research Institute scientists has taken a significant step toward answering that question. The scientists have synthesized for the first time RNA enzymes that can replicate themselves without the help of any proteins or other cellular components, and the... view more... (2009-01-12)
RNA enzyme structure offers a glimpse into the origins of life
Researchers at the University of California, Santa Cruz, have determined the three-dimensional structure of an RNA enzyme, or "ribozyme," that carries out a fundamental reaction required to make new RNA molecules. view more (2007-03-16)
Dengue Virus Reveals Its Circular Secret
The first step in the transmission of mosquito-borne viruses is no mystery: it's the pesky insect's bite that allows the virus to enter its victim's bloodstream. But for some of the most dangerous insect-borne viruses, details of what happens next have been unclear. view more (2006-08-02)
CSHL scientists discover new way in which ubiquitin modifies transcriptional machinery to regulate gene activity
During gene transcription - the process inside the nucleus of cells by which DNA, the genetic material, is copied into RNA - a large, ever-changing multiprotein complex is enlisted to assist the DNA-copying enzyme in its challenging job. view more (2008-12-19)
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