RNA Pathways Current Events | RNA Pathways News
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'Cross-talk' mechanism contributes to colorectal cancer
Researchers at the University of Wisconsin-Madison School of Medicine and Public Health have identified a molecular mechanism that allows two powerful signaling pathways to interact and begin a process leading to colorectal tumors. view more (2009-11-16)
Prediction of RNA pseudoknots using heuristic modeling with mapping and sequential folding
An algorithm utilizing structure mapping and thermodynamics is introduced for RNA pseudoknot prediction. The method finds the minimum free energy in the context of the biological folding direction (5' to 3') of RNA sequences. view more (2007-09-19)
Genome circularization and RNA virus replication
As featured on the cover of the August 15th issue of G&D, an Argentinian research team, led by Dr. Andrea Gamarnik, report on their recent discovery of a novel mechanism of dengue virus replication. view more (2006-08-01)
Researchers discover RNA repair system in bacteria
In new papers appearing this month in Science and the Proceedings of the National Academy of Sciences, University of Illinois biochemistry professor Raven H. Huang and his colleagues describe the first RNA repair system to be discovered in bacteria. view more (2009-10-13)
Immune system response to viral DNA is unique
The human body has a unique immune system response to foreign DNA, suggesting that DNA viruses and RNA viruses are detected by different mechanisms. view more (2006-01-25)
Accelerated evolution converts RNA enzyme to DNA enzyme in vitro
This 'evolutionary conversion' provides a modern-day snapshot of how life as we understand it may have first evolved out of the earliest primordial mix of RNA-like molecules-sometimes referred to as the "pre-RNA world"-into a more complex form of RNA-based life (or the "RNA world") and eventually to cellular life based on DNA... view more... (2006-03-28)
Protein binds whenever it can
Dutch cancer researcher Joost Martens has discovered that the protein p300, which plays an important role in the correct transcription of DNA to RNA, can bind to DNA at several sites. The protein can also occupy a position in various complexes, each with its own protein composition. This knowledge is important for gaining a better understanding of... view more... (2003-06-24)
Molecular typesetting -- proofreading without a proofreader
Researchers at the Universities of Leeds and Bristol (UK) have developed a model of how errors are corrected whilst proteins are being built. view more (2009-06-23)
New insights into how the oncogenic protein c-Myc regulates cell growth
New findings by Swedish and German scientists on the regulation of cellular growth are published in the March issue of Nature Cell Biology. view more (2005-02-20)
Towards a unified model of transcription termination
Dr. David Bentley (University of Colorado School of Medicine) and colleagues have developed a new, unified model for transcription termination by RNA Poymerase II. view more (2006-04-07)
Researchers study signaling networks that set up genetic code
In a new study, researchers at the University of Illinois have identified and visualized the signaling pathways in protein-RNA complexes that help set the genetic code in all organisms. view more (2009-04-15)
Boston University scientists first to see RNA network in live bacterial cells
Scientists who study RNA have faced a formidable roadblock: trying to examine RNA's movements in a living cell when they can't see the RNA. Now, a new technology has given scientists the first look ever at RNA in a live bacteria cell-a sight that could offer new information about how the molecule moves and works. view more (2009-10-23)
Oxford Improves Production Method for Interfering RNA
Researchers at Oxford University's Department of Biochemistry have developed methods for making RNA duplexes and single-stranded RNAs of desired length and sequence. This exciting technology is most applicable to commercial RNA providers and companies with large in-house requirements for RNA molecules as it will greatly increase... view more... (2003-04-29)
A real time look at interactions between RNA and proteins
For the first time, researchers can now peer inside intact cells to not only identify RNA-binding proteins, but also observe-in real-time-the intricate activities of these special molecules that make them key players in managing some of the cell's most basic functions. view more (2006-01-30)
Penn study finds a new role for RNA in human immune response
Researchers at the University of Pennsylvania School of Medicine have published the first study to test the role of RNA chemical modifications on immunity. view more (2005-08-24)
An unexpected link between coronavirus replication and protein secretion in infected cells
Coronavirus replication is critically linked to two factors within the early secretory pathway, according to new findings by a team of Dutch researchers that are published June 13th in the open-access journal PLoS Pathogens. view more (2008-06-13)
RNA found in the cellular centrosome of surf clams
Researchers at Rensselaer Polytechnic Institute, the Marine Biological Laboratory (MBL) in Woods Hole and Louisiana State University (LSU) Health Sciences Center have discovered the presence of the genetic material RNA in the centrosome, the organizing structure inside each cell that assures proper cell division. view more (2006-06-07)
Small molecules may explain psoriasis
A research team at the Swedish medical university Karolinska Institutet has shown for the time that microRNA, small RNA molecules, may play an important role in the development of inflammatory skin diseases such as psoriasis and atopic eczema. view more (2007-07-12)
UCR-led study identifies crucial mechanism involved in immune response against viruses
A research team led by UC Riverside scientists has shown that the common fruit fly can serve as an excellent model for studying the immunity animals are born with for fighting viral infections. view more (2006-03-24)
Non-coding RNAs help silence the mammalian transcription
Dr. Shirley Tilghman and colleagues (Princeton University) lend new insight into the mechanism of genomic imprinting, demonstrating a necessary role for a non-coding RNA transcript in the silencing of an imprinted gene cluster in mice. view more (2006-05-15)
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