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Rectal artemisinins rapidly eliminate malarial parasites
Artemisinin-based suppositories can help 'buy time' for malaria patients who face a delay in accessing effective, injectable antimalarials, according to research published in the online open access journal BMC Infectious Diseases.   view more (2008-03-28)

Artemisinin-based therapy may not be the best treatment for uncomplicated malaria in Africa
A paper published in this month's PLoS Medicine suggests that combination therapy based on artemisinins (one of the newer antimalarial classes of drug) might not be the ideal treatment for uncomplicated malaria in Africa.   view more (2005-07-26)

How to increase the efficacy of local excision of rectal cancer
With the advancement of imaging techniques, the accuracy of preoperative rectal cancer staging has increased dramatically, and the preservation of physical function in rectal cancer patients has become a very important aim of research.   view more (2009-03-20)

PREOPERATIVE RADIOTHERAPY IMPROVES OUTCOME IN RECTAL CANCER (PP 1285, 1291)
Preoperative radiotherapy reduces risk of local recurrence and death from rectal cancer, conclude authors of a systematic overview published in this week's issue of The Lancet. There are different opinions about when it is best to give radiotherapy for rectal cancer. In Scandinavia, the Netherlands, and some other European countries, radiotherapy... view more... (2001-10-17)

Small changes in hospital practice bring significant benefits to rectal cancer patients
Copenhagen, Denmark: Small but important changes in hospital practice during the treatment of rectal cancer can produce significant benefits to patients, according to research from Sweden. Professor Lars P'åhlman, a professor and consultant surgeon at the Department of Surgery at University Hospital Uppsala, Sweden, told delegates at ECCO12... view more... (2003-09-22)

Which is more accurate on diagnosis of rectal carcinoma?
The depth of transmural tumor invasion along the rectal wall layers and involvement of the regional lymph nodes constitute major factors in the prognosis of rectal cancer.   view more (2008-09-25)

Alcohol increases rectal cancer risk, but risk is smaller among regular wine drinkers
Regular drinkers significantly increase their risk of rectal cancer, but that risk is reduced if wine makes up a third or more of weekly consumption, suggests research in Gut. The findings are based on a population study of over 29,000 Danish men and women aged between 23 and 95. Their weekly intake of beer, wine, and spirits was assessed, as were... view more... (2003-05-09)

A feasible, simple and convenient model for study of rectal carcinoma
The method of building a rabbit rectal VX2 carcinoma model by injecting the cell suspension of VX2 cells into the wall of the rectum guided by X-ray fluoroscopy is feasible.   view more (2009-05-13)

What induce local recurrence of rectal carcinoma?
It is well known that local recurrence is the most important prognostic factor of rectal carcinoma. However, even after undergoing radical resection of primary tumors and lymph nodes, about 4%-50% of patients with rectal carcinoma were reportedly with local recurrence.   view more (2008-09-22)

Improved rectal cancer outcome with surgical teaching initiative
High dose radiotherapy before abdominal operations for rectal cancer has been shown to reduce the rate of recurrence of the disease by about half. In this week’s issue of THE Lancet, A Lehander Martling and colleagues from the Karolinska Hospital, Sweden, and Basingstoke, UK, investigated whether this rate could be decreased further by a... view more... (2000-07-05)

Constipation in women linked to anxiety, depression, and feeling "unfeminine"
Chronic constipation in some women is linked to anxiety, depression, and feeling "unfeminine," suggests a study in Gut. Researchers from St Mark's Hospital, Middlesex, studied 34 women between the ages of 19 and 45 who had suffered from constipation for five years or more. The study group was then compared with women who had no history... view more... (2001-07-11)

Ear Thermometry Not Reliable For Precise Measurement Of Infants' Body Temperature (pp 584, 603)
Authors of a systematic review in this week's issue of THE LANCET suggest that measuring infants' body temperature in the ear is not a reliable means of assessing precise body temperature. Infrared ear thermometry is frequently used in children-this is a quick method of taking temperature, and the ear is easily accessible. Rosalind Smyth and... view more... (2002-08-21)

Preoperative radiation may improve survival rates in advanced rectal cancer patients
Patients treated with radiation prior to surgery for advanced rectal cancer have fewer instances of cancer recurrence and better overall survival rates, according to a recent Geisinger report.   view more (2008-12-02)

How to treat pelvic sepsis after stapled hemorrhoidopexy?
In the last decade, stapled hemorrhoidopexy has become increasingly popular and is indicated for the treatment of symptomatic hemorrhoids grade 3 and 4. Stapled hemorrhoidopexy does not remove the hemorrhoids, but it is rather a strip of mucosa and submucosa at the top of the hemorrhoids.   view more (2008-10-24)

Wide variations in appropriateness of rectal cancer surgery across England
A substantial proportion of rectal cancer patients are receiving inappropriate surgical care, because of wide variations in practice across England, reveals research published ahead of print in the journal Gut.   view more (2008-06-05)

Guided radiation therapy for prostate cancer prevents damage to surrounding organs
Oregon Health & Science University Cancer Institute researchers have found that highly targeted radiation therapy for prostate cancer can ensure that the majority of persons with this tumor will not have any long-term rectal damage.   view more (2007-10-29)

Old Stain in a New Combination
New combinations of agents based on the oldest synthetic malaria drug, the methylene blue stain, can curb the spread of malaria parasites and make a significant contribution to the long-term eradication called for by the international "Roll Back Malaria Initiative."   view more (2009-05-21)

MAGNETIC RESONANCE IMAGING COULD BENEFIT RESIDUAL RECTAL-CANCER MANAGEMENT (pp 495, 497)
The technique of magnetic resonance imaging (MRI) could help clinicians identify patients at high risk of recurrence of rectal cancer, conclude authors of a study in this week's issue of THE LANCET. Incomplete surgical removal of rectal cancer (resulting in the formation of circumferential tumour spread) is thought to be the main cause of local... view more... (2001-02-14)

Minimally Invasive Surgery Shown Safe and Effective Treatment for Rectal Cancer
Laparoscopic surgery has been used in the treatment of intestinal disorders for close to 20 years, but its benefits have only recently begun to be extended to people with rectal cancer.   view more (2009-11-11)

BREAST CANCER DOES NOT INCREASE RISK OF COLORECTAL CANCER
Women with a history of breast cancer are not at an increased risk of colorectal cancer, conclude authors of a study published in this week's issue of THE LANCET. A history of breast cancer has been reported as a risk factor for colorectal cancer in women. However, in view of the ambiguous nature of existing evidence and the growing interest in... view more... (2001-03-15)
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