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Technique finds gene regulatory sites without knowledge of regulators
A new statistical technique developed by researchers at the University of Illinois allows scientists to scan a genome for specific gene-regulatory regions without requiring prior knowledge of the relevant transcription factors.   view more (2009-11-20)

Ironing out malnutrition
Two of the three keys are in place to unlock the secret to controlling and enhancing plant iron uptake. Scientists are poised to identify the final step in the process that could supply the world with iron-rich crops. Collaboration between American and French scientists has led to the identification of three key genes involved in iron uptake in... view more... (2001-04-02)

Evolution is driven by gene regulation
It is not just what's in your genes, it's how you turn them on that accounts for the difference between species - at least in yeast - according to a report by Yale researchers in this week's issue of Science.   view more (2007-08-10)

Caltech researchers help unlock the secrets of gene regulatory networks
A quartet of studies by researchers at the California Institute of Technology (Caltech) highlight a special feature on gene regulatory networks recently published in the Proceedings of the National Academy of Sciences (PNAS).   view more (2009-02-04)

Fight against hay fever and other allergies helped by new immune system discovery
A mechanism which can lead to hay fever and other allergic reactions, by preventing the immune system from regulating itself properly, has been discovered by scientists.   view more (2007-12-27)

More 'functional' DNA in genome than previously thought
Surrounding the small islands of genes within the human genome is a vast sea of mysterious DNA. While most of this non-coding DNA is junk, some of it is used to help genes turn on and off.   view more (2007-12-12)

MicroRNA processing and cancer
In an upcoming G&D paper, Dr. Scott Hammond (UNC-Chapel Hill) and colleagues describe a key regulatory step during microRNA biogenesis, which may underlie alterations of microRNA expression in cancer.   view more (2006-08-01)

Strengthening the tumor-fighting ability of T cells
When faced with cancer, the immune system dispatches cells, called T cells, to kill the tumor. But these killer cells often fail to completely eliminate the tumor because they're deactivated by a distinct population of T cells known as regulatory T cells.   view more (2008-03-25)

Making sense of the genome
Almost every week we hear of a new genome sequence being completed, yet turning sequence information into knowledge about what individual genes do is very difficult. An article published in Journal of Biology this week will simplify this task, as it describes a new online tool that dramatically improves predictions of how individual genes are... view more... (2003-05-22)

Has drug regulation abandoned its public health mission?
Over the past 20 years, the pharmaceutical industry has skilfully managed to achieve an unhealthy influence over drug regulatory agencies, which may be threatening the public health needs of the European Union, according to an article in this week's BMJ. Professor John Abraham argues that European regulatory authorities, which were initially... view more... (2002-11-13)

Free shopping in a virtual bazaar of gene regulation data
An international team has opened a virtual bazaar, called PAZAR, which allows biologists to share information about gene regulation through individually managed 'boutiques' (data collections).   view more (2007-10-04)

Whole genome promoter mapping - Human Genome Project v2.0?
nvestigators from the University California, San Diego (UCSD) Branch of the Ludwig Institute for Cancer Research (LICR) and NimbleGen Systems have developed an efficient method to identify thousands of regulatory sequences in the human genome, according to a study published today in Nature.   view more (2005-06-30)

Study finds genetic variant plays role in cleft lip
University of Iowa researchers and collaborators have found, in a previously identified gene, a variation that likely contributes to one in five cases of isolated cleft lip.   view more (2008-10-07)

Master regulatory gene found that guides fate of blood-producing stem cells
Researchers from the University of Pennsylvania School of Medicine found that a protein called NF-Ya activates several genes known to regulate the development of hematopoietic stem cells (HSC), or blood-producing stem cells, in bone marrow.   view more (2005-08-02)

Single gene lets bacteria jump from host to host
All life - plants, animals, people - depends on peaceful coexistence with a swarm of microbial life that performs vital services from helping to convert food to energy to protection from disease.   view more (2009-02-02)

Insight into our sight: A new view on the evolution of the eye lens
The critical component in focusing is the eye lens, and the physical properties that underlie the transparency of the lens, as well as its ability to precisely refract light, arise from the high concentrations of special proteins called crystallins found in lens cells.   view more (2005-09-23)

Key brain regulatory gene shows evolution in humans
Researchers have discovered the first brain regulatory gene that shows clear evidence of evolution from lower primates to humans.   view more (2005-12-13)

Not only the gene itself, its abnormal regulation can also trigger short stature
A specific gene is particularly frequently involved in the development of short stature. Researchers in Heidelberg have now discovered that sequences of genetic material on the X and Y chromosome that regulate this gene are also crucial for growth in children.   view more (2009-08-26)

Prevention is the best option: fighting autoimmune diseases
Centenary scientist Associate Professor Barbara Fazekas de St. Groth, a leader in inflammatory bowel disease research, has demonstrated for the first time the important role of T cells in the prevention of autoimmune diseases in humans.   view more (2006-07-07)

Baffling the body into accepting transplants
An unexpected discovery made by a Sydney scientist has potential to alter the body's response to anything it perceives as not 'self', such as a tissue or organ transplant.   view more (2009-01-21)
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