Regulatory Molecule Current Events | Regulatory Molecule News
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Enzyme inhibitor takes an unexpected approach toward blocking cancer-promoting protein
Scientists at Fox Chase Cancer Center have discovered a unique method of attack that may be used to inhibit signaling enzymes called kinases, which often have a role in sustaining drug-resistant cancerous cells. They have confirmed that IPA-3, a small molecular inhibitor of a kinase called PAK1, targets the enzyme's regulatory domain, mimicking... view more... (2009-09-08)
Finding paves way for better treatment of autoimmune disease
A signaling molecule with an affinity for alcohol has yielded a rapid, inexpensive way to make large numbers of immune cells that work like beat cops to keep misguided cells from attacking the body. view more (2006-08-10)
Strengthening the tumor-fighting ability of T cells
When faced with cancer, the immune system dispatches cells, called T cells, to kill the tumor. But these killer cells often fail to completely eliminate the tumor because they're deactivated by a distinct population of T cells known as regulatory T cells. view more (2008-03-25)
Inflammation contributes to colon cancer
Researchers led by Drs. Lillian Maggio-Price and Brian Iritani at The University of Washington found that mice that lack the immune inhibitory molecule Smad3 are acutely sensitive to both bacterially-induced inflammation and cancer. They report these findings in the January 2009 issue of The American Journal of Pathology. view more (2009-01-22)
Has drug regulation abandoned its public health mission?
Over the past 20 years, the pharmaceutical industry has skilfully managed to achieve an unhealthy influence over drug regulatory agencies, which may be threatening the public health needs of the European Union, according to an article in this week's BMJ. Professor John Abraham argues that European regulatory authorities, which were initially... view more... (2002-11-13)
MicroRNA processing and cancer
In an upcoming G&D paper, Dr. Scott Hammond (UNC-Chapel Hill) and colleagues describe a key regulatory step during microRNA biogenesis, which may underlie alterations of microRNA expression in cancer. view more (2006-08-01)
St. Jude finds molecule that could improve cancer vaccines and therapy for other diseases
Investigators at St. Jude Children's Research Hospital have discovered a new signaling molecule that prevents immune responses from running amok and damaging the body. view more (2007-11-26)
Technique finds gene regulatory sites without knowledge of regulators
A new statistical technique developed by researchers at the University of Illinois allows scientists to scan a genome for specific gene-regulatory regions without requiring prior knowledge of the relevant transcription factors. view more (2009-11-20)
Major breakthrough in transplantation immunity
Australian scientists have made a discovery that may one day remove the need for a lifetime of toxic immunosuppressive drugs after organ transplants. view more (2009-04-07)
Prevention is the best option: fighting autoimmune diseases
Centenary scientist Associate Professor Barbara Fazekas de St. Groth, a leader in inflammatory bowel disease research, has demonstrated for the first time the important role of T cells in the prevention of autoimmune diseases in humans. view more (2006-07-07)
Baffling the body into accepting transplants
An unexpected discovery made by a Sydney scientist has potential to alter the body's response to anything it perceives as not 'self', such as a tissue or organ transplant. view more (2009-01-21)
Starfish-shaped treatments for food poisoning
Embargoed until 19:00 GMT 9 February 2000 view more (2000-02-08)
LGC launches Regulatory Advisory Service for the chemical sector
LGC, the UK`s national centre for analytical measurement, has announced a new advisory service for the chemical sector. Funded through the DTI`s Government Chemist programme, the Regulatory Advisory Service (RAS) at LGC provides free guidance and technical advice to producers and users of chemicals regarding current and emerging chemical and... view more... (2002-10-09)
Fight against hay fever and other allergies helped by new immune system discovery
A mechanism which can lead to hay fever and other allergic reactions, by preventing the immune system from regulating itself properly, has been discovered by scientists. view more (2007-12-27)
Reproduction of fungus depends on ...
A research team of the Department of Applied Chemistry of the University of the Basque Country has been studying the reproduction of funguses. In the laboratory of Unai Ugalde, they have studied and identified a molecule that is essential in the growing of fungus. It is already known that funguses grow in several places, but the factors that... view more... (2002-11-15)
The Pharmaceutical Industry As Political Player (p 1498)
The second of four articles about the relationship between the pharmaceutical industry and medicine focuses on the political dynamic between industry and regulatory authorities. John Abraham from the University of Sussex, Brighton, UK, discusses how political frameworks designed to govern the pharmaceutical industry must, on the... view more... (2002-11-06)
USC researchers discover novel way to develop tumor vaccines
Researchers at the University of Southern California (USC) have uncovered a new way to develop more effective tumor vaccines by turning off the suppression function of regulatory T cells. view more (2008-03-03)
Rough day at work? You won't feel like exercising
Have you ever sat down to work on a crossword puzzle only to find that afterwards you haven't the energy to exercise? Or have you come home from a rough day at the office with no energy to go for a run? view more (2009-09-25)
How actin networks are actin'
Dynamic networks of growing actin filaments are critical for many cellular processes, including cell migration, intracellular transport, and the recovery of proteins from the cell surface. view more (2008-01-03)
Parasite lipids against asthma or diabetes
Dutch research has demonstrated that lipids from the parasite schistosoma can inhibit human immune responses. This property makes the lipids interesting for a possible new treatment of diseases such as asthma and diabetes where the immune system responds inappropriately. During her doctoral research, Desiree van der Kleij discovered that lipids... view more... (2003-11-11)
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