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How actin networks are actin'
Dynamic networks of growing actin filaments are critical for many cellular processes, including cell migration, intracellular transport, and the recovery of proteins from the cell surface.   view more (2008-01-03)

Strengthening the tumor-fighting ability of T cells
When faced with cancer, the immune system dispatches cells, called T cells, to kill the tumor. But these killer cells often fail to completely eliminate the tumor because they're deactivated by a distinct population of T cells known as regulatory T cells.   view more (2008-03-25)

Ironing out malnutrition
Two of the three keys are in place to unlock the secret to controlling and enhancing plant iron uptake. Scientists are poised to identify the final step in the process that could supply the world with iron-rich crops. Collaboration between American and French scientists has led to the identification of three key genes involved in iron uptake in... view more... (2001-04-02)

Has drug regulation abandoned its public health mission?
Over the past 20 years, the pharmaceutical industry has skilfully managed to achieve an unhealthy influence over drug regulatory agencies, which may be threatening the public health needs of the European Union, according to an article in this week's BMJ. Professor John Abraham argues that European regulatory authorities, which were initially... view more... (2002-11-13)

MicroRNA processing and cancer
In an upcoming G&D paper, Dr. Scott Hammond (UNC-Chapel Hill) and colleagues describe a key regulatory step during microRNA biogenesis, which may underlie alterations of microRNA expression in cancer.   view more (2006-08-01)

Scripps research study shows humans and plants share common regulatory pathway
The study was published in an advance online edition of the Proceedings of the National Academy of Sciences during the week of April 9, 2007.   view more (2007-04-10)

Caltech researchers help unlock the secrets of gene regulatory networks
A quartet of studies by researchers at the California Institute of Technology (Caltech) highlight a special feature on gene regulatory networks recently published in the Proceedings of the National Academy of Sciences (PNAS).   view more (2009-02-04)

More 'functional' DNA in genome than previously thought
Surrounding the small islands of genes within the human genome is a vast sea of mysterious DNA. While most of this non-coding DNA is junk, some of it is used to help genes turn on and off.   view more (2007-12-12)

Important new model shows how proteins find the right DNA sequences
Researchers at Uppsala University and Harvard University have collaboratively developed a new theoretical model to explain how proteins can rapidly find specific DNA sequences, even though there are many obstacles in the way on the chromosomes.   view more (2009-03-16)

Technique finds gene regulatory sites without knowledge of regulators
A new statistical technique developed by researchers at the University of Illinois allows scientists to scan a genome for specific gene-regulatory regions without requiring prior knowledge of the relevant transcription factors.   view more (2009-11-20)

Prevention is the best option: fighting autoimmune diseases
Centenary scientist Associate Professor Barbara Fazekas de St. Groth, a leader in inflammatory bowel disease research, has demonstrated for the first time the important role of T cells in the prevention of autoimmune diseases in humans.   view more (2006-07-07)

Probability Controls The Molecule Of Life
Thanks to biophysicists, statistics has reached the most intimate aspect of life - regulation of genes' activity. Investigation on probabilistic aspects of molecular biology has been supported by the Russian Foundation for Basic Research and the INTAS Foundation. Regulation of genes' activity is one of the most important biological problems which... view more... (2004-05-24)

Baffling the body into accepting transplants
An unexpected discovery made by a Sydney scientist has potential to alter the body's response to anything it perceives as not 'self', such as a tissue or organ transplant.   view more (2009-01-21)

Specialized white blood cells coordinate first responders to viral infection
Just as fire engines arrive quickly at the scene to save people and property, the cells that fight viruses have to reach the site of an infection promptly to mount a protective response.   view more (2008-04-25)

Understanding the migration of cancer cells
Lamellipodia are veil-shaped protrusions of the plasma membrane, that can turn into upward-curled ruffles if they fail to adhere to the substrate.   view more (2008-06-23)

'Junk' DNA proves functional
In a paper published in Genome Research on Nov. 4, scientists at the Genome Institute of Singapore (GIS) report that what was previously believed to be "junk" DNA is one of the important ingredients distinguishing humans from other species.   view more (2008-11-05)

St. Jude finds molecule that could improve cancer vaccines and therapy for other diseases
Investigators at St. Jude Children's Research Hospital have discovered a new signaling molecule that prevents immune responses from running amok and damaging the body.   view more (2007-11-26)

Yale researchers make cell biology quantitative
Yale researchers have reported a method to count the absolute number of individual protein molecules inside a living cell, and to measure accurately where they are located, two basic hurdles for studying biology quantitatively.   view more (2005-10-20)

June 25, 2009 A Trio of Signals Converge to Induce Liver and Pancreas Cell Development in the Embryo
Understanding the molecular signals that guide early cells in the embryo to develop into different organs provides insight into ways that tissues regenerate and how stem cells can be used for new therapies.   view more (2009-06-29)

Scientists discover small RNAs that regulate gene expression and protect the genome
RNA is best known as a working copy of the DNA sequence of genes. In this role, it's a carrier of the genes' instructions to the cell, which manufactures proteins according to information in the RNA molecule.   view more (2008-05-14)
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