Replication Infectivity Current Events | Replication Infectivity News
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MicroRNAs help control HIV life cycle
Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specific microRNAs (non-coding RNAs that interfere with gene expression) reduce HIV replication and infectivity in human T-cells. view more (2009-06-26)
Exciting Development in Anti-Retroviral Drug Discovery Made at Oxford
Researchers in Oxford University's Sir William Dunn School of Pathology have developed a novel HTS for identifying antiretroviral (HIV) agents/drugs that inhibit HIV infectivity. Current anti-viral drugs prolong the quality of life for many HIV-1+ individuals, but they do not stop the virus from infecting new cells. Since these drugs mostly... view more... (2003-06-05)
AFRICAN HIV-1 EPIDEMIC NOT CAUSED BY MORE INFECTIOUS VIRAL SUBTYPE (p 1149)
The explosive HIV-1 epidemic in sub-Saharan Africa is unlikely to be the result of a viral subtype with increased infectivity, according to the results of a study published in this week’s issue of THE LANCET. The HIV-1 epidemic in eastern and southern sub-Saharan Africa is mainly caused by HIV-1 subtypes A, C, and D, whereas those in the USA... view more... (2001-04-11)
DNA replication behavior in complex organisms may foreshadow leaps in genomic discoveries
For the first time, findings by scientists at the Genome Institute of Singapore (GIS) may be paving the way for more efficient analyses and tests related to the replication of cells, and ultimately, to the better understanding of human biology, such as in stem cell research. view more (2007-08-16)
Genome circularization and RNA virus replication
As featured on the cover of the August 15th issue of G&D, an Argentinian research team, led by Dr. Andrea Gamarnik, report on their recent discovery of a novel mechanism of dengue virus replication. view more (2006-08-01)
IAH Appoints New Head of Prion Disease Research
The Institute for Animal Health is pleased to announce that Dr Jean Manson has been appointed as Head of TSE Research. Dr Manson will take charge of the transmissible spongiform encephalopathy (TSE) research programme, which is located mainly at the Institute's Neuropathogenesis Unit (NPU) in Edinburgh, but also at the Compton Laboratory. Dr... view more... (2003-02-21)
Nutrition and heredity are genetically linked
A challenging goal in biology is to understand how the principal cellular functions are integrated so that cells achieve viability and optimal fitness under a wide range of nutritional conditions. view more (2007-05-17)
An unexpected link between coronavirus replication and protein secretion in infected cells
Coronavirus replication is critically linked to two factors within the early secretory pathway, according to new findings by a team of Dutch researchers that are published June 13th in the open-access journal PLoS Pathogens. view more (2008-06-13)
Soy isoflavone may inhibit common gastrointestinal illness in infants
The soy isoflavone genistin--at concentrations present in soy infant formula-- may reduce a baby's susceptibility to rotavirus infections by as much as 74 percent. view more (2007-09-07)
Novel mechanism for DNA replication discovered
Since the discovery of the structure of DNA by James Watson and Francis Crick in 1953, the paradigm for DNA replication has stated that the DNA itself codes for the appropriate pairings for replication. view more (2005-09-30)
MU Researcher Refining Synthetic Molecules to Prevent HIV Resistance
Evolving HIV viral strains and the adverse side effects associated with long-term exposure to current treatments propel scientists to continue exploring alternative HIV treatments. view more (2008-12-17)
New Strategy for Inhibiting Virus Replication
Viruses need living cells for replication and production of virus progeny. Thus far, antiviral therapy primarily targets viral factors but often induces therapy resistance. New improved therapies attempt to targets cellular factors that are essential for viral replication. view more (2009-08-17)
Gene expression profiling of dengue virus infection in cell lines and patients
Researchers at the Novartis Institute for Tropical Diseases and the Genome Institute of Singapore have identified new host genes associated with dengue virus infection, which may open new avenues to developing a drug to treat the disease. view more (2007-11-07)
The hepatitis healing power of blueberry leaves
A chemical found in blueberry leaves has shown a strong effect in blocking the replication of the Hepatitis C virus, opening up a new avenue for treating chronic HCV infections, which affect 200 million people worldwide and can eventually lead to cirrhosis and liver cancer. view more (2009-08-10)
Biologists discover link between CGG repeats in DNA and neurological disorders
Researchers have long known that some repetitive DNA sequences can make human chromosomes "fragile," i.e. appearing constricted or even broken during cell divisions. view more (2009-01-12)
Interferons For Treatment Of SARS? (p 293)
Authors of a research letter in this week's issue of THE LANCET suggest that recombinant interferons - synthetic versions of naturally occurring compounds of the immune system - could be a an effective treatment for Severe Acute Respiratory Syndrome (SARS). Although antivirals are probably essential for the treatment of SARS-CoV infection, the... view more... (2003-07-23)
Selenium may slow march of AIDS
Increasing the production of naturally occurring proteins that contain selenium in human blood cells slows down multiplication of the AIDS virus, according to biochemists. view more (2008-12-01)
Handle with care: Telomeres resemble DNA fragile sites
Telomeres, the repetitive sequences of DNA at the ends of linear chromosomes, have an important function: They protect vulnerable chromosome ends from molecular attack. view more (2009-07-10)
UNC scientists discover cellular 'SOS' signal in response to UV skin damage
New research from the University of North Carolina at Chapel Hill School of Medicine has identified two proteins that may help protect against skin cancer. view more (2007-03-19)
Details of the life cycle of SARS coronavirus
A team of scientists studying Severe Acute Respiratory Syndrome (SARS) has, for the first time, described how the SARS virus manufactures several of the materials required for making copies of itself. "It is essential, when you are looking for ways to stop a disease, that you know exactly how viruses make copies of themselves and... view more... (2003-07-08)
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