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Reprogramming Human Cells Without Inserting Genes
A research team comprised of faculty at Worcester Polytechnic Institute's (WPI) Life Sciences and Bioengineering Center (LSBC) and investigators at CellThera, a private company also located at the LSBC, has discovered a novel way to turn on stem cell genes in human fibroblasts (skin cells) without the risks associated with inserting extra genes or... view more... (2009-07-30)
Strengthening the tumor-fighting ability of T cells
When faced with cancer, the immune system dispatches cells, called T cells, to kill the tumor. But these killer cells often fail to completely eliminate the tumor because they're deactivated by a distinct population of T cells known as regulatory T cells. view more (2008-03-25)
Getting better with a little help from our 'micro' friends
A naturally occurring molecule made by symbiotic gut bacteria may offer a new type of treatment for inflammatory bowel disease, according to scientists at the California Institute of Technology. view more (2008-05-29)
Penn Scientists Use RNA to Reprogram One Cell Type into Another
For the past decade, researchers have tried to tweak cells at the gene and nucleus level to reprogram their identity. Now, working on the idea that the signature of a cell is defined by molecules called messenger RNAs, which contain the chemical blueprint for how to make a protein, researchers at the University of Pennsylvania School of Medicine,... view more... (2009-04-17)
Stem cells in adult testes provide alternative to embryonic stem cells for organ regeneration
Easily accessed and plentiful, adult stem cells found in a male patient's testicles might someday be used to create a wide range of tissue types to help him fight disease -- getting around the need for more controversial embryonic stem cells. view more (2007-09-20)
New discovery about the formation of new brain cells
The generation of new nerve cells in the brain is regulated by a peptide known as C3a, which directly affects the stem cells' maturation into nerve cells and is also important for the migration of new nerve cells through the brain tissue, reveals new research from the Sahlgrenska Academy published in the journal Stem Cells. view more (2009-11-24)
'Nurse cells' make life and death decisions for infection-fighting cells
"Nurse cells" play an important role in deciding which developing infection-fighting cells, called T cells, live and which die, according to research funded by the National Science Foundation (NSF) and reported in the June issue of the journal Experimental Biology and Medicine. view more (2007-05-31)
Preventing overload in the brain
Brain researchers in Amsterdam have observed a double control system in the hippocampus. This double control system contributes to the memory and ensures that the brain does not `crash`, as is the case during an epileptic seizure. The neurobiologists from the University of Amsterdam carried out their observations on the hippocampus of rats. The... view more... (2002-01-29)
A new method for bone-marrow-derived liver stem cells isolation and proliferation
Great interest has been aroused in the identification and isolation of liver stem cells from bone marrow cells. Several subsets of bone marrow cells have been found to have the potential to differentiate into hepatocytes, however, sorting based on immunological methods is difficult because of the complicated surface markers of the stem cells;... view more... (2009-04-15)
The new source of islet cells
The shortage of islet cells limits the development of islet transplantation. One new approach was reported in the October 21 issue of the World Journal of Gastroenterology because of its great significance in enhancing the output of islet cells. This article will undoubtedly bring benefit to diabetic patients. view more (2007-10-25)
OU Cancer Institute Scientists Identify New Cancer Stem Cell Marker; Developing Drug to Stop Cancer Recurrence
After years of working toward this goal, scientists at the OU Cancer Institute have found a way to isolate cancer stem cells in tumors so they can target the cells and kill them, keeping cancer from returning. view more (2008-09-12)
Heart derived stem cells develop into heart muscle
Dutch researchers at University Medical Center Utrecht and the Hubrecht Institute have succeeded in growing large numbers of stem cells from adult human hearts into new heart muscle cells. view more (2008-04-24)
Researchers discover key mechanism to emergence of deadly strep bacteria
The incidence of serious strep infections has risen dramatically in the last three decades, and this increase is largely attributed to the spread around the globe of a single strain of strep known as the invasive M1T1 clone. view more (2007-07-16)
Antibody-altering protein found in developing B cells
In order for the B cells of the immune system to identify and fight disease pathogens, they produce a protein called activation-induced cytidine deaminase (AID). view more (2007-07-20)
Shedding light on cancer cells
Scientists label cells with coloured or glowing chemicals to observe how basic cellular activities differ between healthy and cancerous cells. Existing techniques for labelling cells are either too slow or too toxic to perform on live cells. view more (2009-09-25)
Protein identified that turns off HIV-fighting T cells
In HIV-infected patients the body's immune system is unable to fight off the virus. A new study to be published online on November 10th in the Journal of Experimental Medicine shows that T cells in HIV-infected individuals express a protein called TIM-3, which inactivates their virus killing capacity. view more (2008-11-10)
Afib triggered by a cell that resembles a pigment-producing skin cell
The source and mechanisms underlying the abnormal heart beats that initiate atrial fibrillation (Afib), the most common type of abnormal heart beat, have not been well determined. view more (2009-10-13)
Tapping into spinal cures
Stem cells which give rise to vertebrae, muscle and the spinal cord have been identified for the first time by Dr. Valerie Wilson (University of Edinburgh). "These axial stem cells could be used in the future to help replace damaged tissues after back injuries", says Dr. Wilson who will be presenting her work at the Society for... view more... (2004-03-26)
Durable critters providing insight for human egg preservation
A tiny, six-legged critter that suspends all biological activity when the going gets tough may hold answers to a better way to cryopreserve human eggs, researchers say. view more (2006-12-19)
Toward a nanomedicine for brain cancer
In an advance toward better treatments for the most serious form of brain cancer, scientists in Illinois are reporting development of the first nanoparticles that seek out and destroy brain cancer cells without damaging nearby healthy cells. view more (2009-09-10)
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