Reprogramming Genes Current Events | Reprogramming Genes News
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Converting adult somatic cells to pluripotent stem cells using a single virus
A Boston University School of Medicine-led research team has discovered a more efficient way to create induced Pluripotent Stem (iPS) cells, derived from mouse fibroblasts, by using a single virus vector instead of multiple viruses in the reprogramming process. view more (2009-01-08)
DFG remains skeptical of the cloning of human cells
According to a paper published in the journal Stem Cells, an American group has succeeded in inserting cell nuclei from human skin cells into human enucleated oocytes and to stimulate these new cells to undergo cell division in the laboratory. view more (2008-01-23)
Stanford scientists turn adult skin cells into muscle and vice versa
In a study featured on the cover of the May issue of The FASEB Journal, researchers describe how they are able to reprogram human adult skin cells into other cell types in order to decipher the elusive mechanisms underlying reprogramming. view more (2009-04-30)
Scripps research scientists identify compounds for stem-cell production from adult cells
In the study, the scientists screened known drugs and identified small molecules that could replace conventional reprogramming genes, which can have dangerous side effects. view more (2008-11-06)
Recipe for cell reprogramming adds protein
A drug-like molecule called Wnt can be substituted for the cancer gene c-Myc, one of four genes added to adult cells to reprogram them to an embryonic-stem-cell-like state. view more (2008-08-07)
Molecular alliance that sustains embryonic stem cell state
One of the four ingredients in the genetic recipe that scientists in Japan and the U.S. followed last year to persuade human skin cells to revert to an embryonic stem cell state, is dispensable in ES cells, thanks to the presence of a molecular alliance between a specific group of key proteins known as transcription factors. view more (2008-03-05)
Fate Therapeutics announces creation of small molecule platform for commercial-scale reprogramming
Fate Therapeutics, Inc. announced today the generation of human induced-pluripotent stem cells (iPSCs) using a combination of small molecules that significantly improves the speed and efficiency of reprogramming. view more (2009-10-19)
UCLA researchers reprogram normal tissue cells into embryonic stem cells
Researchers at the Institute for Stem Cell Biology and Medicine at UCLA were able to take normal tissue cells and reprogram them into cells with the same unlimited properties as embryonic stem cells, the cells that are able to give rise to every cell type found in the body. view more (2007-06-07)
Scientists identify embryonic stem cells by appearance alone
Some scientific results are hard to spot, especially in genetic research. Often scientists are unable to physically see if the gene they inserted into a cell has produced the desired trait. view more (2007-08-28)
Embryonic stem cell strategy advanced with UCSF finding
UCSF scientists are reporting what they say is a significant improvement in the technique for genetically reprogramming mouse cells to their embryonic state, a process that transforms the cells, in essence, into embryonic stem cells. view more (2007-09-11)
Environmental exposures may damage DNA in as few as 3 days
Exposure to particulate matter has been recognized as a contributing factor to lung cancer development for some time, but a new study indicates inhalation of certain particulates can actually cause some genes to become reprogrammed, affecting both the development and the outcome of cancers and other diseases. view more (2009-05-18)
Animal eggs not suitable substitutes to produce stem cells
Since the cloning of Dolly the Sheep over a decade ago, somatic cell nuclear transfer (SCNT) has been considered a promising way to generate human, patient-specific stem cells for therapeutic applications. view more (2009-02-03)
Tumor suppressor pulls double shift as reprogramming watchdog
A collaborative study by researchers at the Salk Institute for Biological Studies uncovered that the tumor suppressor p53, which made its name as "guardian of the genome", not only stops cells that could become cancerous in their tracks but also controls somatic cell reprogramming. view more (2009-08-10)
Researchers piggyback to safer reprogrammed stem cells
Austin Smith and his research team at the Centre for Stem Cell Research in Cambridge have just published in the journal Development (http://dev.biologists.org/) a new and safer way of generating pluripotent stem cells - the stem cells that can give rise to every tissue of the body. view more (2009-02-27)
Researchers devise new technique for creating human stem cells
Researchers have developed a new technique for creating human embryonic stem cells by fusing adult somatic cells with embryonic stem cells. view more (2005-08-23)
Early estrogen exposure leads to later prostate cancer risk
A study in the June 1 issue of Cancer Research presents the first evidence that exposure to low doses of environmental estrogens during development of the prostate gland in the male fetus may result in a predisposition to prostate cancer later in life. view more (2006-06-01)
New Method Developed by UC San Diego Bioengineers Gives Regenerative Medicine a Boost
Bioengineers at UC San Diego have developed a breakthrough method for sequencing-based methylation profiling, which could help fuel personalized regenerative medicine and even lead to more efficient and cost-effective methods for studying certain diseases. view more (2009-04-24)
'Liposuction leftovers' easily converted to IPS cells, Stanford study shows
Globs of human fat removed during liposuction conceal versatile cells that are more quickly and easily coaxed to become induced pluripotent stem cells, or iPS cells, than are the skin cells most often used by researchers. view more (2009-09-08)
Yamanaka eliminates viral vector in stem cell reprogramming
Shinya Yamanaka MD, PhD, of Kyoto University and the Gladstone Institute of Cardiovascular Disease (GICD) has taken another step forward in improving the possibilities for the practical application of induced pluripotent stem (iPS) cell technology. view more (2008-10-13)
USC researchers explore genetic causes for male infertility
Researchers at the University of Southern California (USC) suggest epigenetics, or the way DNA is processed and expressed, may be the underlying cause for male infertility. The study will be published in the Dec. 12 issue of Public Library of Science One. view more (2007-12-12)
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