Rheumatology Current Events | Rheumatology News | 4
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NEJM editorial on significance and limitations of new lupus gene expression research
Some 1.5 million Americans, most of them women, suffer from lupus, a disease where the person's immune system attacks the body's own tissue. view more (2008-01-21)
Low carbohydrate diet did not increase bone loss, study finds
A strict low-carbohydrate diet had no effect on bone loss for adults following an Adkins-type diet for weight loss, a three-month study by rheumatologists at the University of South Florida found. view more (2006-05-25)
First multinational study of Tocilizumab reports in
Nearly half (43.9%) of rheumatoid arthritis (RA) patients receiving tocilizumab 8mg/kg, in addition to ongoing methotrexate therapy experienced a 50% (ACR50) improvement in symptoms at 24 weeks and more than one fifth achieved a 70% symptom improvement. view more (2007-06-18)
Drug for rheumatism possible boon to heart patients
Atheromatosis, which lies behind heart attacks, stroke, and other cardiovascular problems, has a major impact on public health. So does chronic rheumatoid arthritis. These two diseases are completely different from each other, but they do have one common denominator: inflammation. Researchers at Lund University in Sweden can now show that it might... view more... (2004-10-08)
Increasing evidence that osteoporosis begins in the womb
Recent evidence to suggest that osteoporosis has its origins in the womb will be presented by leading expert, Professor Cyrus Cooper, when he speaks at a symposium on osteoporosis at FOAD 2003, the Second World Congress on the Fetal Origins of Adult Diseases (FOAD), which takes place at the Brighton Conference Centre next month (7 - 10 June).... view more... (2003-05-22)
Antibody therapy prevents type 1 diabetes in mice
University of Pittsburgh investigators have successfully prevented the onset of type 1 diabetes in mice prone to developing the disease using an antibody against a receptor on the surface of immune T-cells. According to the investigators. view more (2007-01-09)
Why don't painkillers work for people with fibromyalgia?
People who have the common chronic pain condition fibromyalgia often report that they don't respond to the types of medication that relieve other people's pain. view more (2007-09-28)
Abatacept and infliximab improve clinical response over time in methotrexate-refractory RA patients
New data presented today at EULAR 2008, the Annual Congress of the European League Against Rheumatism in Paris, France, show that over half of rheumatoid arthritis patients resistant to methotrexate monotherapy improved when either abatacept or infliximab were added to their methotrexate treatment regimen, with positive results sustained up to one... view more... (2008-06-16)
50 percent of recent onset RA patients become free of signs and symptoms within 36 weeks
At least 50% of recent onset rheumatoid arthritis patients achieve remission (a state free of signs and symptoms) within 36 weeks when following a systematic approach of step-up DMARD treatment in combination with tight control. view more (2008-06-12)
Combination drug therapy could substantially improve symptoms of rheumatoid arthritis (pp 670, 675)
The combination of two drugs - both partly effective for rheumatoid arthritis patients when given individually - could be an important development in substantially reducing symptoms and joint destruction for people with rheumatoid arthritis, conclude authors of a study in this week's issue of THE LANCET. Rheumatoid arthritis affects around 1% of... view more... (2004-02-25)
Landmark observational study aims to improve osteoporosis care standards worldwide
Nearly 60,000 women aged 55 years and older have enrolled in a landmark, multi-national study that will focus on the management of osteoporosis across the globe. view more (2008-04-10)
Pain in fibromyalgia is linked to changes in brain molecule
Researchers at the University of Michigan Health System have found a key linkage between pain and a specific brain molecule, a discovery that lends new insight into fibromyalgia, an often-baffling chronic pain condition. view more (2008-03-11)
Smoking, low levels of education and glucose tolerance increase risk of rheumatoid arthritis
New data presented today at EULAR 2007, the Annual European Congress of Rheumatology in Barcelona, Spain, sheds light on the role of environmental and genetic risk factors in the development of rheumatoid arthritis (RA). view more (2007-06-18)
Infliximab May Offer Hope For Patients Living With Spondyloarthropathy
For the first time, there may be an effective therapeutic option for severe cases of spondyloarthropathies (SpA), a group of rheumatic inflammatory diseases that affect the spinal column, peripheral joints and tendons. The study, published in the March 6 issue of "Arthritis and Rheumatism", found that patients treated with infliximab (also known... view more... (2002-03-07)
Bone erosion reduced by denosumab in phase 2 trial
reatment with denosumab 60 mg and 180 mg (with background methotrexate) reduces the progression of bone erosion according to results of a 227 patient Phase II trial. view more (2007-06-18)
Pediatric researchers find possible 'master switch' gene in juvenile arthritis
Researchers have found that a gene region known to play a role in some varieties of adult rheumatoid arthritis is also present in all types of childhood arthritis. The researchers say the responsible gene may be a "master switch" that helps turn on the debilitating disease. view more (2008-07-02)
Fibromyalgia pain caused by neuron mismatch, suggests study
The unexplained pain experienced by patients with fibromyalgia is the result of a mismatch between sensory and motor systems, new research suggests. view more (2007-10-31)
Genes in the interferon system important in SLE
Two genes with very strong associations with the disease SLE have been identified by a team of scientists headed by researchers at the Department of Medical Sciences at Uppsala University. The findings are being published today on the Web page of the highly prestigious American Journal of Human Genetics. "These findings are probably the... view more... (2005-01-19)
Telephone questionnaire makes best use of resources
Telephone-based questionnaires, administered by trained lay-people, could prove more accurate and less costly than current case detection surveys for rheumatoid disease, French researchers said today. Speaking at the Press Conference during EULAR 2001, the prestigious annual congress of the European League Against Rheumatism (EULAR), Professor... view more... (2001-06-14)
Exercise improves functional and psycological ability and reduces steroid need in rheumatoid arthritis
Undertaking a supervised exercise programme can have beneficial effects on functional status and physical function, reduce the need for daily corticosteroid and anti-inflammatory intake and improve levels of depression and anxiety in people with rheumatoid arthritis (RA). view more (2009-06-11)
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