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RiboTargets joins Partnership for Structural Biology at the European Synchrotron Radiation Facility
RiboTargets, the structure-based drug discovery company that develops novel cancer and anti-bacterial therapeutics, announced today that it has joined the new Partnership for Structural Biology (PSB) established at the European Synchrotron Radiation Facility (ESRF). Associate membership of the PSB will provide guaranteed access to beamlines at... view more... (2003-01-24)

Researchers uncover details about how dietary restriction slows down aging
University of Washington scientists have uncovered details about the mechanisms through which dietary restriction slows the aging process.   view more (2008-04-18)

Translational derepression & oncogene expression in breast cancer cells
Drs. Anuradha Mehta, Christopher Trotta and Stuart Peltz (PTC Therapeutics) have uncovered a novel mechanism whereby the translation efficiency of oncogenes is increased in cancer cells.   view more (2006-03-31)

Researchers discover how antibiotic inhibits bacterial growth
Researchers at the University of Illinois at Chicago, in collaboration with research teams from Pharmacia & Upjohn and Pfizer, have discovered precisely how the antibiotic linezolid inhibits bacterial growth.   view more (2007-05-11)

National Science Foundation congratulates Nobel Laureates in medicine/physiology, chemistry and economics
The National Science Foundation (NSF) congratulates the 2009 Nobel laureates, particularly those who have received NSF funding over the years: Jack W. Szostak, who shared the prize in physiology or medicine; Thomas A. Steitz, who shared the prize in chemistry; and Elinor Ostrom and Oliver E. Williamson who earned the Sveriges Riksbank Prize in... view more... (2009-10-15)

NIST researchers 'all aglow' over new test of toxin strength
A new National Institute of Standards and Technology (NIST) assay using a "glow or no glow" technique may soon help the U.S. Department of Homeland Security (DHS) defend the nation against a spectrum of biological weapons that could be used in a terrorist attack.   view more (2009-06-18)

UCLA researchers outline the structure of the largest non-virus particle ever crystallized
Researchers at UCLA, the California NanoSystems Institute, the David Geffen School of Medicine, and the Howard Hughes Medical Institute have modeled the structure of the largest cellular structure ever crystallized, suggesting ways to engineer the particles for drug delivery.   view more (2007-11-27)

Researchers reveal insights into hidden world of protein folding
The proteins upon which life depends share an attribute with paper airplanes: Unless folded properly, they just won't fly.   view more (2008-06-12)

Life's origins were easier than was thought
In the primordial soup that produced life on earth, there were organic molecules that combined to produce the first nucleic acid chains, which were the first elements able to self-replicate.   view more (2005-09-16)

Genetic sleuth solves glaucoma mystery
Dr. Michael Walter is one good gumshoe. The University of Alberta medical geneticist has cracked the case of WDR36, a gene linked to glaucoma.   view more (2009-03-20)

Researchers identify proteins involved in new neurodegenerative syndrome
The interplay of two proteins that bind to messenger RNA, a molecule that mediates translation of the information encoded in genes into proteins, triggers the appearance of fragile X-associated tremor/ataxia syndrome (FTAX), a late-life disorder associated with the gene that causes fragile X syndrome in children.   view more (2007-08-16)

Mutations within a conservative region of HCV affects the therapy
At least 200 million individuals are currently infected with hepatitis C virus (HCV) worldwide. Approximately 30%-50% of patients respond to interferon/ribavirin combination therapy.   view more (2009-03-31)

Researchers outline structure of largest nonvirus particle ever crystallized
Researchers at UCLA's California NanoSystems Institute, the David Geffen School of Medicine at UCLA and the Howard Hughes Medical Institute have modeled the structure of the largest cellular particle ever crystallized, suggesting ways to engineer the particles for drug delivery.   view more (2007-11-27)

Genes Against By-Product-Coking Industry
How can workers be protected from detrimental production factors? Russian researchers have come to the conclusion that this can be done by a large number of actively working ribosomal genes.   view more (2005-02-22)

New Insights into the Mechanisms of Rapamycin
Rapamycin is a new drug which is being used for preventing organ rejection in kidney transplant patients. Since it suppresses the immune response and has a strong cell killing effect, it is a highly interesting substance for potential use in other disease areas such as cancer, autoimmune diseases, and diabetes mellitus. A recent publication of the... view more... (2004-04-07)

2-pronged protein attack could be source of SARS virulence
Ever since the previously unknown SARS virus emerged from southern China in 2003, University of Texas Medical Branch at Galveston virologists have focused on finding the source of the pathogen's virulence - its ability to cause disease.   view more (2009-10-30)

Researchers solve mystery of how nuclear pores duplicate before cell division
Researchers have long wondered how nuclear pores - the all-important channels that control the flow of information in and out of a cell's nucleus - double in number to prepare for the split to come when a cell divides.   view more (2006-04-21)

Study finds protein is required for human chromosome production
Scientists at the University of North Carolina at Chapel Hill School of Medicine have identified an elusive protein that performs a necessary step in the production of human chromosomes.   view more (2005-10-13)

Basic work on E. coli identifies two new keys to regulation of bacterial gene expression
The cellular process of transcription, in which the enzyme RNA polymerase constructs chains of RNA from information contained in DNA, depends upon previously underappreciated sections of both the DNA promoter region and RNA polymerase, according to work done with the bacterium E. coli.   view more (2006-06-19)
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