SARS without pneumonia could be common in outbreak areas (p 841)
Results of research from Hong Kong in this week's issue of THE LANCET suggests that severe acute respiratory syndrome (SARS) without pneumonia could be common among populations affected by SARS outbreaks. SARS has now affected 30 countries in five continents, with more than 8400 cases and more than 910 deaths. A novel virus, the... view more... (2004-03-10)
A Different Antiviral For Treating SARS (p 2045)
A preliminary study published as a fast-track research letter in this week's issue of THE LANCET suggests that the antiviral agent glycyrrhizin could be more effective than other antivirals in the treatment of severe acute respiratory syndrome (SARS). Ribavirin is the most commonly used antiviral for treating SARS infection, used in combination... view more... (2003-06-11)
SARS antiviral drug discovered: traditional antimalarial drug works against SARS coronavirus infection
Virologists from the Katholieke Universiteit Leuven (K.U.Leuven) in Belgium report that chloroquine, a widely used antimalarial drug, exhibits antiviral activity against the SARS coronavirus. Chloroquine is an inexpensive and safe drug available worldwide. SARS (Severe Acute Respiratory Syndrome) is a respiratory illness which was first... view more... (2004-09-03)
Surgical Masks Offer Best Protection For Hospital Workers In Contact With Sars Patients (p 1519)
Research from Hong Kong in this week's issue of THE LANCET emphasises how severe acute respiratory syndrome (SARS) is spread by droplet infection, with surgical masks providing the best protection for health-care workers exposed to patients with SARS. W H Seto from Queen Mary Hospital, Hong Kong, and colleagues assessed the precautions taken by... view more... (2003-04-30)
Interferons For Treatment Of SARS? (p 293)
Authors of a research letter in this week's issue of THE LANCET suggest that recombinant interferons - synthetic versions of naturally occurring compounds of the immune system - could be a an effective treatment for Severe Acute Respiratory Syndrome (SARS). Although antivirals are probably essential for the treatment of SARS-CoV infection, the... view more... (2003-07-23)
Airport screening unlikely to prevent spread of SARS or influenza
Screening passengers as they arrive at UK airports is unlikely to prevent the importation of either SARS or influenza, finds a study published online by the BMJ today. view more (2005-09-23)
Novel Coronavirus Confirmed As Causative Agent Of SARS
Leading scientists worldwide investigating the cause of Severe Acute Respiratory Syndrome (SARS) confirm that a novel coronavirus is the primary cause of the disease. The study is published on THE LANCET's website (www.thelancet.com) at 0001 H Tuesday 22 July UK time. SARS was first reported in China in November 2002, with over 8300 cases and 812... view more... (2003-07-18)
Animal model shows early promise for SARS vaccine (p 1895)
Embargoed 0001 h (London time) 5 December 2003. US authors of a research letter in this week's issue of THE LANCET highlight preliminary findings which could mark an important step in the development of a human vaccine for severe acute respiratory syndrome (SARS). A genetically engineered vaccine was found to be effective in triggering an immune... view more... (2003-12-03)
Animal studies show promise for development of human SARS immunisation (pp 2102, 2122, 2139)
An article and research letter in this week's issue of THE LANCET provide evidence for the effectiveness of experimental SARS immunisation in animal studies. Although further research is required, these preliminary results show the potential for the development of human SARS immunisation. Alexander Bukreyev from the US National Institutes of... view more... (2004-06-23)
Details of the life cycle of SARS coronavirus
A team of scientists studying Severe Acute Respiratory Syndrome (SARS) has, for the first time, described how the SARS virus manufactures several of the materials required for making copies of itself. "It is essential, when you are looking for ways to stop a disease, that you know exactly how viruses make copies of themselves and... view more... (2003-07-08)
High pollution may increase SARS death rate
Air pollution is associated with an increased risk of dying from SARS, according to a report published this week in Environmental Health: A Global Access Science Source. The study shows that patients with SARS are more than twice as likely to die from the disease if they come from areas where pollution levels are high. 5,327 cases of SARS have... view more... (2003-11-18)
Common SARS policy for schools urgently needed
The Government should urgently develop a common SARS policy for UK boarding schools, according to a letter in this week's BMJ. Current school policies on SARS are confusing, writes Ian Wong at the University of London School of Pharmacy. Some Chinese students are subjected to quarantine imposed by their schools, while one school is reported to be... view more... (2003-04-23)
Guidelines on SARS should be refined
Haematological manifestations in patients with severe acute respiratory syndrome: retrospective analysis BMJ Volume 326, pp 1358-62 Current World Health Organisation (WHO) guidelines for diagnosing suspected SARS may not be sufficiently sensitive in assessing patients before admission to hospital, suggest researchers from Hong Kong in this week's... view more... (2003-06-18)
SARS could very well return this autumn, leading experts predict
SARS could return this autumn, predict some leading public health experts, but it is unlikely to be on the scale of an epidemic. view more (2003-07-15)
Study Implicates Human Coronavirus As Main Cause Of SARS
Early online publication: Tuesday 8 April 2003 FOR IMMEDIATE RELEASE Research from Hong Kong fast-tracked for publication on THE LANCET's website--www.thelancet.com--provides evidence that a new virus belonging to the family Coronaviridae is likely to be the main cause of Severe Acute Respiratory Syndrome (SARS). Malik Peiris from the University... view more... (2003-04-08)
Researchers find 'secret weapon' used by SARS virus
In 2003, the highly contagious and often-deadly mystery disease now called SARS emerged explosively out of Southern China. It eventually killed an estimated 916 people in Asia, Europe, and North and South America-nearly one in ten of those it infected. view more (2006-08-08)
Lung Damage From SARS Could Be From Immune Response To Infection
Results of a three-week follow-up study of 75 people with SARS from the Amoy Garden housing block in Hong Kong provide a new insight into the progression of severe acute respiratory syndrome (SARS). The study, fast-tracked for early publication, is published on THE LANCET'S website - www.thelancet.com A major outbreak of SARS involving 321... view more... (2003-05-08)
New Study Shows SARS Can Infect Brain Tissue
Severe acute respiratory syndrome (SARS), by its very name, indicates a disease of the respiratory tract. view more (2005-09-15)
Household transmission of SARS: Lessons learned
In the 2003 outbreak of severe acute respiratory syndrome (SARS) in Toronto, Ontario, about 20% of cases resulted from household transmission (spread of the infection within a household). view more (2006-11-07)
Enzyme inhibitors block replication Of SARS virus
Researchers have known since 2003 that a site on the virus is responsible for mediating proteases that allow the virus to replicate. Since then researchers have been testing protease inhibitors to lock up this site, known as SARS 3CLpro, and effectively stop the virus from infecting additional cells in the body. view more (2006-03-28)
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