SARS without pneumonia could be common in outbreak areas (p 841)
Results of research from Hong Kong in this week's issue of THE LANCET suggests that severe acute respiratory syndrome (SARS) without pneumonia could be common among populations affected by SARS outbreaks. SARS has now affected 30 countries in five continents, with more than 8400 cases and more than 910 deaths. A novel virus, the... view more... (2004-03-10)
SARS antiviral drug discovered: traditional antimalarial drug works against SARS coronavirus infection
Virologists from the Katholieke Universiteit Leuven (K.U.Leuven) in Belgium report that chloroquine, a widely used antimalarial drug, exhibits antiviral activity against the SARS coronavirus. Chloroquine is an inexpensive and safe drug available worldwide. SARS (Severe Acute Respiratory Syndrome) is a respiratory illness which was first... view more... (2004-09-03)
Study Implicates Human Coronavirus As Main Cause Of SARS
Early online publication: Tuesday 8 April 2003 FOR IMMEDIATE RELEASE Research from Hong Kong fast-tracked for publication on THE LANCET's website--www.thelancet.com--provides evidence that a new virus belonging to the family Coronaviridae is likely to be the main cause of Severe Acute Respiratory Syndrome (SARS). Malik Peiris from the University... view more... (2003-04-08)
A Different Antiviral For Treating SARS (p 2045)
A preliminary study published as a fast-track research letter in this week's issue of THE LANCET suggests that the antiviral agent glycyrrhizin could be more effective than other antivirals in the treatment of severe acute respiratory syndrome (SARS). Ribavirin is the most commonly used antiviral for treating SARS infection, used in combination... view more... (2003-06-11)
Details of the life cycle of SARS coronavirus
A team of scientists studying Severe Acute Respiratory Syndrome (SARS) has, for the first time, described how the SARS virus manufactures several of the materials required for making copies of itself. "It is essential, when you are looking for ways to stop a disease, that you know exactly how viruses make copies of themselves and... view more... (2003-07-08)
Interferons For Treatment Of SARS? (p 293)
Authors of a research letter in this week's issue of THE LANCET suggest that recombinant interferons - synthetic versions of naturally occurring compounds of the immune system - could be a an effective treatment for Severe Acute Respiratory Syndrome (SARS). Although antivirals are probably essential for the treatment of SARS-CoV infection, the... view more... (2003-07-23)
SARS From Outer Space? (p 1832)
An alternative theory to the origin of severe acute respiratory syndrome (SARS) is proposed by scientists in a letter in this week's issue of THE LANCET--that the disease may have originated in outer space. Chandra Wickramasinghe from Cardiff University, UK, and colleagues describe how around a tonne of bacteria is deposited on the earth every... view more... (2003-05-21)
Researchers find 'secret weapon' used by SARS virus
In 2003, the highly contagious and often-deadly mystery disease now called SARS emerged explosively out of Southern China. It eventually killed an estimated 916 people in Asia, Europe, and North and South America-nearly one in ten of those it infected. view more (2006-08-08)
Animal model shows early promise for SARS vaccine (p 1895)
Embargoed 0001 h (London time) 5 December 2003. US authors of a research letter in this week's issue of THE LANCET highlight preliminary findings which could mark an important step in the development of a human vaccine for severe acute respiratory syndrome (SARS). A genetically engineered vaccine was found to be effective in triggering an immune... view more... (2003-12-03)
Novel Coronavirus Confirmed As Causative Agent Of SARS
Leading scientists worldwide investigating the cause of Severe Acute Respiratory Syndrome (SARS) confirm that a novel coronavirus is the primary cause of the disease. The study is published on THE LANCET's website (www.thelancet.com) at 0001 H Tuesday 22 July UK time. SARS was first reported in China in November 2002, with over 8300 cases and 812... view more... (2003-07-18)
Researchers recreate SARS virus, open door for potential defenses against future strains
Researchers at the University of North Carolina at Chapel Hill and Vanderbilt University Medical Center have synthetically reconstructed the bat variant of the SARS coronavirus (CoV) that caused the SARS epidemic of 2003.
view more (2008-11-26)
Variants Of SARS Virus Gives Clues To Origin Of Infection
A genetic study of the SARS virus fast-tracked for publication on THE LANCET's website-www.thelancet.com-gives an insight into the molecular behaviour of the novel coronavirus responsible for SARS. Comparison of a virus isolate from Singapore with isolates from other countries where SARS has struck suggests that there are main components of the... view more... (2003-05-08)
SARS: No evidence that any of the treatments worked
The SARS virus set alarm bells ringing across the world when it first appeared in 2002, but now a review of the effectiveness of the treatments used against it has found no evidence that any of them worked. view more (2006-09-12)
Finding SARS-CoV virus in many parts of the body leads to calls for more stringent infection control measures
New research in two papers published this week in The Journal of Pathology gives greater insight into why the virus is so deadly, and shows that it could transfer from person to person via breath, urine, faeces and even sweat. Searching for SARS Scientists in China used markers that only bind to SARS-CoV to analyse tissues from four people who had... view more... (2004-05-05)
Protein from algae shows promise for stopping SARS
A protein from algae may have what it takes to stop Severe Acute Respiratory Syndrome (SARS) infections, according to new research. view more (2009-05-21)
SARS could very well return this autumn, leading experts predict
SARS could return this autumn, predict some leading public health experts, but it is unlikely to be on the scale of an epidemic. view more (2003-07-15)
Animal studies show promise for development of human SARS immunisation (pp 2102, 2122, 2139)
An article and research letter in this week's issue of THE LANCET provide evidence for the effectiveness of experimental SARS immunisation in animal studies. Although further research is required, these preliminary results show the potential for the development of human SARS immunisation. Alexander Bukreyev from the US National Institutes of... view more... (2004-06-23)
Surgical Masks Offer Best Protection For Hospital Workers In Contact With Sars Patients (p 1519)
Research from Hong Kong in this week's issue of THE LANCET emphasises how severe acute respiratory syndrome (SARS) is spread by droplet infection, with surgical masks providing the best protection for health-care workers exposed to patients with SARS. W H Seto from Queen Mary Hospital, Hong Kong, and colleagues assessed the precautions taken by... view more... (2003-04-30)
Enzyme inhibitors block replication Of SARS virus
Researchers have known since 2003 that a site on the virus is responsible for mediating proteases that allow the virus to replicate. Since then researchers have been testing protease inhibitors to lock up this site, known as SARS 3CLpro, and effectively stop the virus from infecting additional cells in the body. view more (2006-03-28)
Common SARS policy for schools urgently needed
The Government should urgently develop a common SARS policy for UK boarding schools, according to a letter in this week's BMJ. Current school policies on SARS are confusing, writes Ian Wong at the University of London School of Pharmacy. Some Chinese students are subjected to quarantine imposed by their schools, while one school is reported to be... view more... (2003-04-23)
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