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Kaposi sarcoma arises independently from multiple cells
Kaposi sarcoma is unique among cancers because most tumors grow from a small number of different cells, whereas nearly all other cancers arise from a single cell.   view more (2007-07-11)

Dual functions of gene revealed, for better and for worse
Researchers at WEHI have pinpointed the function of a potent cancer gene. The gene, known as "ERG", has long been associated with a range of human malignancies, including leukemia and sarcoma. American scientists showed in 2005 that ERG is mutated in more than half of all prostate... view more (2008-05-27)

Inhibition of iron-metabolizing enzyme reduces tumor growth
A report in the Journal of Biological Chemistry shows that inhibition of heme oxygenase-1, an enzyme involved in iron metabolism, reduces Kaposi sarcoma tumor growth.   view more (2006-04-21)

Childhood cancer survivors at increased risk of sarcoma
Survivors of childhood cancers have a ninefold increased risk of developing a secondary sarcoma—a cancer of connective or supportive tissue such as bone, fat, or muscle—compared with the general population.   view more (2007-02-21)

Landmark discovery of a Kaposi's sarcoma-associated herpesvirus receptor
Researchers at the National Institute of Allergy and Infectious Disease (NIAID), a component of the National Institutes of Health (NIH), have identified a critical human cell surface molecule involved in infection by Kaposi's sarcoma herpesvirus (KSHV), the virus that causes Kaposi's sarcoma and... view more (2006-04-07)

Interesting lead in the treatment of Ewing`s sarcoma
Research scientists at INSERM, CNRS and the Institut Curie, in collaboration with physicians, have used a mouse model to demonstrate the efficacy of an innovative therapeutic approach to Ewing`s sarcoma: the combination of human interferon (alpha or beta) and a common anti-tumor agent, ifosfamide.... view more (2002-10-31)

Ewing's sarcoma : Discovery of a "link" in tumor growth
To develop new therapeutic approaches to cancer, it is essential to understand the long and extremely complex process that underlies it, in other words the various stages of cancer development from the initial mutation to the tumor. Having already identified the alteration that leads to Ewing's... view more (2004-09-23)

Marijuana component opens the door for virus that causes Kaposi's sarcoma
The major active component of marijuana could enhance the ability of the virus that causes Kaposi's sarcoma to infect cells and multiply.   view more (2007-08-02)

New understanding of Ewing's sarcoma suggests novel treatment strategy
Using molecular and cell-based models, researchers at Georgetown University Medical Center have refined the picture of how a cancer-promoting protein associated with Ewing's sarcoma functions.   view more (2006-06-01)

Specific treatments for each type of sarcoma
The new molecular techniques allow designing specific treatments for a great number of sarcomas, according to Dr. Enrique de Alava, expert of the department of Pathologic Anatomy of the University Clinic of the University of Navarre. The molecular knowledge has become a very useful tool to study... view more (2002-11-29)

Researchers find that childhood sarcoma increases risk of blood clots
Researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, have determined that children and young adults with a form of cancer called sarcoma are at increased risk of having a thromboembolic event (TE) in their veins.   view more (2007-04-19)

UF scientists identify cancer virus' genetic targets
University of Florida researchers have identified specific human genes targeted by a virus believed to cause Kaposi's sarcoma, a rare form of cancer associated with AIDS and with organ transplants that causes patches of red or purple tissue to grow under people's skin.   view more (2007-05-11)

First report that apoptotic and anti-angiogenic therapies work better together than alone
American researchers have found that giving a combination of imantanib (Glivec) and a drug that induces cell death (apoptosis) was better at inhibiting the growth of Ewing's sarcoma in mice than either therapy on its own.   view more (2006-11-13)

New way of tracking muscle damage from radiation
Magnetic resonance imaging (MRI) could become a valuable tool for predicting the risk of muscle injury during and following radiation therapy.   view more (2006-11-07)

In lab study, researchers find molecule that disrupts Ewing's sarcoma oncogene
Researchers at Georgetown University Medical Center have found a small molecule they say can block the action of the oncogene that causes Ewing's sarcoma, a rare cancer found in children and young adults. If further studies continue to prove beneficial, they say the novel agent could be the first... view more (2008-04-14)

Finnish scientists discovered a new approach to treat virus-induced lymphomas
Kaposi's sarcoma herpesvirus (KSHV) is a human tumor virus and an etiological agent for Kaposi's sarcoma and primary effusion lymphoma (PEL).   view more (2007-03-16)

An AIDS-related virus tricks cells to become tumors, new Penn study finds
Researchers at the University of Pennsylvania School of Medicine have discovered how the Kaposi's sarcoma-associated herpesvirus (KSHV) subverts a normal cell process in order to promote tumor growth.   view more (2006-11-09)

Survey reports fall in stem cell transplants for breast cancer
The use of stem cell transplantation in breast cancer treatment soared in the early and mid 1990s but the dramatic fall that begin in 1997 as clinical trials showed it appeared to be of little benefit continues, according to new figures published in the April edition of Annals of Oncology[1].... view more (2004-03-30)

Cancer researchers seek safe reduction of radiotherapy
University of Manchester scientists will discuss their research aimed at reducing the side effects of radiotherapy without decreasing its effectiveness at the National Cancer Research Institute conference in Birmingham.   view more (2007-10-03)

An AIDS-related virus reveals more ways to cause cancer, Penn researchers find
Researchers at the University of Pennsylvania School of Medicine have shed new light on how Kaposi's Sarcoma-associated Herpes Virus (KSHV) subverts normal cell machinery to cause cancer.   view more (2007-10-09)

Potential viral therapy weapon for difficult cancers is safe and effective in study
Combining a herpes virus genetically altered to express a drug-enhancing enzyme with a chemotherapy drug effectively and safely reduced the size of highly malignant human sarcoma grafted into mice.   view more (2008-04-23)

Mice lacking key immune component still control chronic viral infections
Despite lack of a key component of the immune system, a line of genetically engineered mice can control chronic herpes virus infections, researchers at Washington University School of Medicine in St. Louis have found.   view more (2006-05-30)

Researchers report the cloning of a key group of human genes, the protein kinases
Although the human genome has been sequenced, research into mechanism of action of genes has been hampered by the fact that most human genes have not been isolated. This is true for even the most common class of cancer-associated genes, the protein kinases, which mediate the majority of signaling... view more (2008-05-05)

Blood transfusion-transmitted infections: A global perspective
Thanks to the many blood-safety interventions introduced since 1984, the overall risk for most transfusion-transmitted infections has become exceedingly small.   view more (2006-09-28)

Kidney transplantation linked with increased risk of various cancers
Following kidney transplantation, some recipients may face a 3-fold increased risk of certain cancer types, according to a study in the December 20 issue of JAMA.   view more (2006-12-20)
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