Sepsis Current Events | Sepsis News | 2
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Scientists discover a direct route from the brain to the immune system
It used to be dogma that the brain was shut away from the actions of the immune system, shielded from the outside forces of nature. But that's not how it is at all. In fact, thanks to the scientific detective work of Kevin Tracey, MD, it turns out that the brain talks directly to the immune system, sending commands that control the body's... view more... (2007-10-24)
HIV accessory protein disables host immunity via receptor-protein intermediary
Researchers at the University of Pennsylvania School of Medicine discovered that an HIV-1 accessory protein called Vpr destroys the host cell's ability to survive by binding to a host receptor. view more (2006-03-31)
Older men more likely than women to die after pneumonia
Differing biological response to infection between men and women may explain higher death rates among older men who are hospitalized with community-acquired pneumonia (CAP). view more (2009-04-30)
Early warning for acute kidney injury
Clinicians currently lack advance warning of acute kidney injury (AKI) for patients where kidney injury timing is unknown. view more (2007-08-02)
Ashwell receptor reduces mortality during sepsis
In research that solves the longest-standing mystery in glycobiology - a field that studies complex sugar chains called glycans - researchers at the University of California, San Diego School of Medicine have discovered that a molecule in the liver of all animals, called the Ashwell receptor, is critical in helping the body fight off the abnormal... view more... (2008-05-19)
New study finds on/off switch for septic shock
According to a new study, septic shock-a dangerous, often deadly runaway immune response-is controlled by a genetic on/off switch view more (2006-11-15)
Researchers identify new weapon to fight deadly bacterial sepsis
One of the most dangerous risks of contracting a serious bacterial infection is that the victim may develop sepsis-an overreaction by the immune system causing destructive inflammation throughout the body, often leading to heart and other organ failure and death. view more (2006-10-10)
Scientists figure out how the immune system and brain communicate to control disease
In a major step in understanding how the nervous system and the immune system interact, scientists at The Feinstein Institute for Medical Research have identified a new anatomical path through which the brain and the spleen communicate. view more (2008-07-22)
Gene chip technology shows potential for identifying life-threatening blood infection
Right now there's no rapid way to diagnose sepsis, a fast-moving blood infection that is a leading cause of death in hospital intensive care units. The illness unleashes a powerful inflammatory response that can quickly overwhelm the body, causing organ failure and death, often within days. view more (2006-12-20)
Packard/Stanford study suggests two causes for bowel disease in infants
New research from Lucile Packard Children's Hospital and the Stanford University School of Medicine is helping physicians unravel the cause of a deadly and mysterious bowel disease that strikes medically fragile newborn babies. view more (2009-04-27)
Key to out-of-control immune response in lung injury found
Researchers at the University of Illinois at Chicago College of Medicine have discovered how a protein modulates the inflammatory response in sudden, life-threatening lung failure. The protein's previously unknown role is reported in the August issue of Nature Medicine. view more (2007-08-17)
Scripps scientists studying sepsis in mice find potential drug targets for deadly disease
"We have identified a key connection of signaling pathways in the cascade of events leading to sepsis. This defines a crucial point where the immune system spirals out of control to cause severe sepsis and where there is an opportunity for therapeutic intervention," says Scripps Research Professor Wolfram Ruf, who led the research with... view more... (2008-02-28)
Strategies for preventing gastrointestinal complications in severely burned patients
Gastrointestinal dysfunction is a common complication of severe burns. Injury to GI function, especially to GI barrier function, is an important initiator as well as a stimulator for occurrence of systemic inflammatory response syndrome, sepsis and multiple organ dysfunction syndrome following severe burns. view more (2008-09-18)
DRUG MAY HELP REDUCE SEVERE CONSEQUENCES OF MENINGOCOCCAL SEPSIS (pp 954, 961)
A modified version of a protein found within white blood cells could help to decrease the severe complications of meningococcal sepsis, according to the results of a trial published in this week's issue of THE LANCET. The bacterium Neisseria meningitidis (also known as the meningococcus) causes meningitis, but can also result in sepsis-a... view more... (2000-09-14)
Researchers block immune cell rush behind deadly sepsis
Researchers have found a way to block the ability of white blood cells to sprint toward the sites of infection when such speed worsens the damage done by sepsis, the often fatal, whole-body bacterial infection, according to a study published today in the journal Blood. view more (2009-02-25)
Key protein regulating inflammation may prove relevant to controlling sepsis
Scientists at Singapore's Institute of Molecular and Cell Biology (IMCB), under the Agency for Science, Technology and Research (A*STAR), have identified the protein, WIP1, as the molecular "brake" that curbs severe inflammation in the body. view more (2009-05-15)
Corticosteroids associated with poor outcomes, death in the trauma intensive care unit
Patients in the trauma intensive care unit who receive corticosteroids may have more infections, longer stays in intensive care or on a ventilator and a higher death rate than those who do not. view more (2006-02-21)
Adult sickle cell drug proves effective in young children
A drug used for the treatment of sickle cell anemia in adults has now been shown to cause significant improvements in very young children with the disorder. view more (2005-09-20)
First high-res 3D structures of mammalian HSP90 protein solved
Dr. Dan Gewirth, Hauptman-Woodward senior research scientist, has just solved the structure of the first mammalian GRP94 protein implicated in immune diseases such as sepsis, AIDS and certain cancers. view more (2007-10-15)
BUSM researchers find gram-negative rods in two Philippine neonatal intensive care units
Researchers at Boston University School of Medicine (BUSM) have found a high frequency of multidrug-resistant Gram-negative rods (GNRs) in two of the largest neonatal intensive care units (NICUs) in the city of Manila, Philippines. view more (2009-05-18)
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