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Warning for women who binge drink
As levels of binge drinking in the UK rise, doctors in this week's BMJ report three cases of bladder rupture in women who attended hospital with lower abdominal pain.   view more (2007-11-12)

Doctors launch new effort to treat stroke more effectively
Just a small fraction of patients who have a stroke receive the only drug - TPA - available to treat the condition. Now doctors and scientists at the University of Rochester Medical Center have developed a potential new treatment that will reach a milestone in the next few months, when the experimental treatment is tested for the first time in... view more... (2006-11-03)

Scientists identify a septic shock susceptibility gene
Septic shock often follows a bacterial infection, and is characterized by the overwhelming release of pro-inflammatory cytokines by the body's immune system.   view more (2006-11-03)

MRSA toxin acquitted: Study clears suspected key to severe bacterial illness
Researchers who thought they had identified the bacterial perpetrator of the often severe disease caused by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) had better keep looking: Scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have exonerated a... view more... (2006-11-07)

Large burns open up a can of worms
Large burns can trigger cardiac problems and enhanced inflammatory and hypermetabolic responses in patients, a study in the online open access journal Critical Care suggests. Effective treatments may need to focus on these multiple aspects.   view more (2007-08-23)

Pathogenic soil bacterium is influenced by land management practices
Researchers from Menzies School of Health Research in Darwin, Australia have found that the soil bacterium Burkholderia pseudomallei, which causes the emerging infectious disease melioidosis in humans and animals, is associated with land management changes such as livestock husbandry or residential gardening.   view more (2009-01-21)

Discovery of a 'molecular switch' could lead to new ways of treating infection, including MRSA
The discovery of a 'molecular switch' could lead to new ways of treating infections such as MRSA, and inflammatory diseases like arthritis.   view more (2005-04-26)

Ethnicity plays a role in neonatal deaths
Researchers have uncovered ethnic differences in the risk of neonatal mortality and morbidity (disease) in the neonatal intensive care units (NICU). Of grave concern is the noted elevation in mortality rate in the NICU among infants of South Asian (East Indian) origin, which is over three times that of Caucasian infants.   view more (2007-07-24)

Bacteria that cause urinary tract infections invade bladder cells
Scientists at Washington University School of Medicine in St. Louis have found definitive proof that some of the bacteria that plague women with urinary tract infections (UTIs) are entrenched inside human bladder cells.   view more (2007-12-18)

Mechanism proposed for link between RU-486 and fatal infections
The abortion drug mifepristone (Mifeprex,TM RU-486) has been linked to rare cases of fatal bacterial infections, but until now the connection has not been clearly understood.   view more (2005-07-27)

Continuous infusion of hydrocortisone reduces hyperglyaemia in patients with septic shock
Changing how critically ill patients are treated with hydrocortisone could reduce hyperglycemia.   view more (2007-02-16)

Day-care services could be option for pregnancy complications (pp 1089, 1104)
Research from Australia in this week's issue of THE LANCET highlights how day-care services could offer some benefits over hospital admission for women with pregnancy complications. Day care is increasingly being used for complications of pregnancy, despite little evidence that it is effective. Deborah Turnbull from the University of Adelaide,... view more... (2004-03-31)

Is it worth having surgery to remove your tonsils?
Adults with recurrent sore throats may benefit from having a tonsillectomy in the short term, but the overall longer term benefit is still unclear, and any benefits have to be balanced against the side effects of the operation, according to this week's BMJ.   view more (2007-05-04)

Why could ethyl pyruvate attenuate severe acute pancreatitis?
Excessive activation of inflammatory mediator cascade during SAP is a major cause of distant organ injury and the high mortality.    view more (2008-10-13)

First analysis of FDA's mifepristone adverse event reports
The abortion drug mifepristone (Mifeprex,TM RU-486), initially touted as a more convenient alternative to surgical abortion, has been linked to serious adverse reactions, including several deaths in otherwise healthy women.   view more (2005-12-29)

Community MRSA is re-emergence of 1950s pandemic, study suggests
An early type of antibiotic-resistant bacteria that caused a global epidemic of infections in the 1950s has re-emerged as one of the community-acquired MRSA 'superbugs', according to a study published in this weeks issue of The Lancet.   view more (2005-03-31)

Researchers find possible target to treat deadly bloodstream infections
Researchers at the University of Illinois at Chicago have discovered a possible target to treat bloodstream bacterial infections.   view more (2008-02-29)

Blood sugar control before surgery associated with fewer infections afterward
Patients with diabetes who have good control of blood glucose levels before having surgery may be less likely to have infections after their procedures.   view more (2006-04-18)

Portal vein thrombosis is common in extraportal vein obstruction
Among the 118 patients with portal vein thrombosis, noncirrhotic and nontumoral extrahepatic portal vein obstruction are young and present with well tolerated bleed.   view more (2007-10-15)

MGH study identifies enzyme that protects against intestinal bacterial toxin
A persistent mystery in human medicine is how the lining of the small intestine, through which nutrients are absorbed, also prevents intestinal bacteria and their toxins from entering the bloodstream and causing serious infections.   view more (2008-02-19)
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