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Sunlight and serotonin underlie seasonal mood disorders
Authors of a research letter in this week's issue of THE LANCET provide further evidence that the effect of sunlight on neurotransmitters in the brain plays a significant role in seasonal mood disorders. The success of phototherapy (ultraviolet light therapy to stimulate brain neurotransmitter activity) and drugs that prevent the reuptake of the... view more... (2002-11-29)

Women At Greater Risk Of Brain-Cell Damage From Long-Term Ecstasy Use
Authors of a Dutch study in this week's issue of THE LANCET conclude that long-term ecstasy use-especially among women-could have serious negative effects on specific cells in the brain. The study also suggests that the adverse effects of ecstasy use can sometimes be reversed among people who stop using the drug. Ecstasy is a popular recreational... view more... (2001-11-28)

Sex differences in the brain's serotonin system
A new thesis from he Swedish medical university Karolinska Institutet shows that the brain�s serotonin system differs between men and women. The scientists who conducted the study think that they have found one of the reasons why depression and chronic anxiety are more common in women than in men.   view more (2008-02-14)

Gene variations contribute to aggression and anger in women
Ever wonder why some women seem to be more ill-tempered than others? University of Pittsburgh researchers have found that behaviors such as anger, hostility and aggression may be genetic, rooted in variations in a serotonin receptor gene.   view more (2007-03-12)

Fluctuations in serotonin transport may explain winter blues
Why do many Canadians get the winter blues? In the first study of its kind in the living human brain, Dr. Jeffrey Meyer and colleagues at the Centre for Addiction and Mental Health (CAMH) have discovered greater levels of serotonin transporter in the brain in winter than in summer.   view more (2008-09-09)

PET scans help identify mechanism underlying seasonal mood changes
Brain scans taken at different times of year suggest that the actions of the serotonin transporter-involved in regulating the mood-altering neurotransmitter serotonin-vary by season, according to a report in the September issue of Archives of General Psychiatry, one of the JAMA/Archives journals.   view more (2008-09-02)

Some antipsychotic drugs may be missing their mark
Drugs that treat depression, schizophrenia and other psychotic conditions and that target a particular protein on brain cells might not be triggering the most appropriate response in those cells, new research suggests.   view more (2008-01-02)

Functional brain imaging in the dog.
Single photon emission tomography is an imaging modality using radiolabelled tracer substances to investigate function and metabolism of various organs in the living patient. We explored this technique in the dog to investigate brain function. Brain perfusion (an indirect indicator for metabolism and related brain function) was measured in normal... view more... (2003-02-04)

Similar brain chemicals influence aggression in fruit flies and humans
Serotonin is a major signaling chemical in the brain, and it has long been thought to be involved in aggressive behavior in a wide variety of animals as well as in humans. Another brain chemical signal, neuropeptide Y (known as neuropeptide F in invertebrates), is also known to affect an array of behaviors in many species, including territoriality... view more... (2007-04-23)

Lack of happiness hormone serotonin in the brain causes impaired maternal behavior in mice
A lack of serotonin, commonly known as the "happiness hormone", in the brain slows the growth of mice after birth and is responsible for impaired maternal behavior later in life.   view more (2009-06-24)

Serotonin may play role in hardening of the arteries
A less active brain serotonin system is associated with early hardening of the arteries, according to a study presented today by University of Pittsburgh researchers at the 64th Annual Scientific Conference of the American Psychosomatic Society in Denver.   view more (2006-03-06)

Researchers lift a corner of the veil of depression
About 1 in 10 Europeans has to contend with some form of depression during his or her life. But how people become depressed is still largely a mystery.   view more (2006-03-16)

New clues to how major weight-loss drugs work
Some of the most important weight-loss drugs work by enhancing the effect of the brain chemical serotonin. These include sibutramine (trade name Meridia) and fenfluramine, which was recalled after the combination with dexfenfluramine, called fen-phen, was linked to potentially fatal heart valve abnormalities.   view more (2006-07-20)

UVA Researchers Uncover Gene's Role in Severity of Drinking
New research from the University of Virginia Health System could help explain why some alcoholics are more severe drinkers than others. A UVA team has found strong evidence that the serotonin transporter gene, SLC6A4, plays a significant role in influencing drinking intensity among alcohol-dependent individuals.    view more (2009-02-05)

Taste test may identify best drugs for depression
New research has shown that it might be possible to use taste as an indicator as to whether someone is depressed, and as a way of determining which is the most suitable drug to treat their depression.   view more (2006-12-06)

Pular antidepressants boost brain growth, Hopkins scientists report
The beneficial effects of a widely used class of antidepressants might be the result of increased nerve-fiber growth in key parts of the brain, according to a Johns Hopkins study being published in the January 2006 issue of the Journal of Neurochemistry.   view more (2005-12-20)

Rotating shift workers have lower levels of serotonin
People who work rotating shifts have significantly lower levels of serotonin, a hormone and neurotransmitter in the central nervous system believed to play an important role in the regulation of sleep.   view more (2007-08-01)

Commonly used antidepressants may also affect human immune system
Drugs that treat depression by manipulating the neurotransmitter serotonin in the brain may also affect the user's immune system in ways that are not yet understood, say scientists from Georgetown University Medical Center and a Canadian research institute.   view more (2006-01-20)

Sticky blood protein yields clues to autism
Many children with autism have elevated blood levels of serotonin - a chemical with strong links to mood and anxiety. But what relevance this "hyperserotonemia" has for autism has remained a mystery.   view more (2008-03-05)

Women more depressed and men more impulsive with reduced serotonin functioning
Women and men appear to respond differently to the same biochemical manipulation. Major depressive disorder (MDD) is one of the most common mental disorders, and it is also one of the most studied.   view more (2007-09-18)
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