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Sickle Cell Current Events | Sickle Cell News | 3

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Males May Experience Greater Physical Pain Due To Lower Levels Of A Key Protein, Endothelin
Agonizing physical pain, known as vaso-occlusive pain, can afflict children who have sickle cell disease (SCD).   view more (2009-09-10)

Statistical tool could explain gene study variations
While scientists are using the human genome to associate certain genes with disease, Dr. Hongyan Xu wants to ensure they are accounting for natural variations in those genes.   view more (2008-05-29)

NHS policies fail to strike a balance between equity and efficiency
The NHS is facing a dilemma between the goals of equity and efficiency. An editorial in this week's BMJ reports that there is no consensus on how to deal with policies that may cause conflict, often leading to inconsistent judgements in the development of health policies. The authors cite several examples of inconsistency among current NHS... view more... (2001-10-03)

Scientists find genetic pathway that could lead to drugs for kidney disease
Scientists at the University of California, Santa Barbara have reported a discovery at the cellular level that suggests possibilities for drug therapy for kidney disease.   view more (2006-02-01)

UVA Researchers Study Link Between "Alzheimer's Gene"
Researchers at the University of Virginia School of Medicine and Federal University of CearĂ¡ in Brazil have joined forces to study if the gene believed to contribute to Alzheimer's protects children from the developmental stresses of early childhood diarrhea.   view more (2006-11-13)

Individuals with genetic conditions twice as likely to report health insurance denial
A new study published in the February 2007 issue of the American Journal of Medical Genetics reveals that individuals with genetic conditions are twice as likely to report having been denied health insurance than individuals with other chronic illnesses.   view more (2007-02-13)

Children's Hospital Oakland scientists first to discover new source for harvesting stem cells
A groundbreaking study conducted by Children's Hospital & Research Center Oakland is the first to reveal a new avenue for harvesting stem cells from a woman's placenta, or more specifically the discarded placentas of healthy newborns.   view more (2009-06-23)

Anticancer drugs might be of benefit to sickle-cell patients
Sickle cell disease (SCD) is an inherited blood disorder caused by a genetic mutation that leads to the generation of a mutant form of the beta-globin chain of hemoglobin (Hb).   view more (2007-12-07)

New research into the mechanisms of gene regulation
A team led by Penn State's Ross Hardison, T. Ming Chu Professor of Biochemistry and Molecular Biology, has taken a large step toward unraveling how regulatory proteins control the production of gene products during development and growth.   view more (2009-11-20)

Neurological disease raises risk of complications from flu
As another flu season approaches, patients with neurological and neuromuscular disease are especially vulnerable to respiratory failure caused by influenza.   view more (2005-11-02)

Researchers Shed Light on Evolution of Gene Regulation
Scientists at Penn State have shed light on some of the processes that regulate genes -- such as the processes that ensure that proteins are produced at the correct time, place, and amount in an organism -- and they also have shed light on the evolution of the DNA regions that regulate genes.   view more (2008-11-25)

New finding may aid adult stem cell collection
Cincinnati scientists have discovered how blood-regenerating stem cells move from bone marrow into the blood stream.   view more (2005-07-28)

Scientists discover novel way to remove iron from ferritin
A new study led by Children's Hospital Oakland Research Institute senior scientist, Elizabeth Theil, Ph.D., is the first to suggest that a small protein or heptapeptide (seven amino acids wrapped into one unit) could be used to accelerate the removal of iron from ferritin.   view more (2007-11-05)

New stem cell technique improves genetic alteration
UC Irvine researchers have discovered a dramatically improved method for genetically manipulating human embryonic stem cells, making it easier for scientists to study and potentially treat thousands of disorders ranging from Huntington's disease to muscular dystrophy and diabetes.   view more (2008-03-10)

New guideline for prescribing opioid pain drugs published
A national panel of pain management experts representing the American Pain Society (APS) and the American Academy of Pain Medicine (AAPM) has published the first comprehensive, evidence-based clinical practice guideline to assist clinicians in prescribing potent opioid pain medications for patients with chronic non-cancer pain.   view more (2009-02-09)

Simulated gene therapy
In a recent issue of The Journal of Chemical Physics, published by the American Institute of Physics (AIP), a group of researchers at the University of California, Berkeley and Los Alamos National Laboratory describe the first comprehensive, molecular-level numerical study of gene therapy.   view more (2009-04-30)

UK leads race to produce world's first clinical grade stem cells
The University of Sheffield has received a £2.6m grant to create some of the world's first embryonic stem cell lines that can be used for medicinal purposes.   view more (2005-03-16)

The importance of gene regulation for common human disease
A new study published in Nature Genetics on Sunday 16 September 2007 show that common, complex diseases are more likely to be due to genetic variation in regions that control activity of genes, rather than in the regions that specify the protein code.   view more (2007-09-17)

Embryo's heartbeat drives blood stem cell formation
Biologists have long wondered why the embryonic heart begins beating so early, before the tissues actually need to be infused with blood.   view more (2009-05-14)

Major 'missed' biochemical pathway emerges as important in virtually all cells
A new study by Duke University researchers provides more evidence that the nitric oxide (NO) system in the life of a cell plays a key role in disease, and the findings point to ways to improve treatment of illnesses such as heart disease and cancer.   view more (2008-05-23)
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