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Isolation of a new gene family essential for early development
Researchers at BRIC, University of Copenhagen, have identified a new gene family (UTX-JMJD3) essential for embryonic development. The family controls the expression of genes crucial for stem cell maintenance and differentiation, and the results may contribute sig-nificantly to the understanding of the development of cancer. view more (2007-08-23)
Researchers Find Defects in Adult Stem Cell Niche May Cause Breast Cancer
Researchers at Georgetown's Lombardi Comprehensive Cancer Center have found that the onset of breast cancer may be due to defects in somatic adult stem cell niches that exist long before tumors develop. view more (2005-10-05)
Scientists deconstruct cell division
The last step of the cell cycle is the brief but spectacularly dynamic and complicated mitosis phase, which leads to the duplication of one mother cell into two daughter cells. In mitosis, the chromosomes condense and the nucleus breaks down. view more (2009-02-09)
Child-proof: Brain mapping safer for children than previously thought, Hopkins study shows
Dispelling a stubborn myth, researchers at Johns Hopkins have shown that children with strokes, brain tumors and other cerebrovascular diseases can safely undergo a potentially life-saving brain-mapping test that many doctors have long shunned over concerns for side effects. view more (2006-10-09)
Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state
For more than 25 years, stem cells have been defined based on what they can become: more of themselves, as well as multiple different specialized cell types. view more (2007-06-20)
UC HEALTH LINE: Spirituality May Help Adolescents Cope With Chronic Illness
Chronic illness can lead to poorer quality of life-particularly for adolescents. New research shows that spirituality may help teens cope with their conditions. view more (2009-01-09)
Unstable proteins can cause premature ageing
The normal ageing process has long been linked to problems with cell respiration, the process through which the cells extract energy from nutrients. view more (2009-08-06)
The small cell neuroendocrine carcinoma of the ampulla of vater
Ampullary small cell neuroendocrine carcinoma is extremely rare and has only been documented in few case reports and retrospective study. The patients with ampullary small cell neuroendocrine carcinoma usually presented after the age of 60 years, and a male predilection was observed. view more (2008-09-25)
Use eggs, not embryos, to derive stem cells, say researchers
Concerns about the ethics of using embryos created to treat infertile couples for stem cell research is discussed by researchers at St Mary's Hospital, Manchester in this week's BMJ. Although the Human Fertilisation and Embryology Act 1990 allows the creation of embryos for research in the United Kingdom, the House of Lords Select Committee on... view more... (2003-10-08)
What are protective effects of anti-ricin A-chain aptamer?
Ricin, a lectin from the castor bean plant Ricinus communis is considered one of the most potent plant toxins. Ricin poisoning can cause severe tissue damage and inflammation and can result in death. view more (2008-12-29)
Compound reveals new link between signaling protein and cell migration
University of Illinois at Chicago researchers report that a protein that regulates key signaling pathways in cells also plays a role in controlling the active movement or migration of cells. view more (2005-09-26)
UAB Study Shows Drug May Fight Biliary Cancers
Laboratory studies by University of Alabama at Birmingham (UAB) researchers have shown that the drug triphendiol (NV-196) causes cell death in pancreatic and bile duct cancer cell lines, slows tumor growth and sensitizes tumors to chemotherapy treatments. view more (2008-04-16)
What is the pathogenesis of liver damage induced by ethanol?
They investigated the effects of ethanol on the IGF-I system with the involvement of JNK1/2 activity and ADH by using each chemical inhibitor in primary cultured rat hepatocytes. The results indicate that ethanol inducedp-JNK1/2 activation is associated with the IGF-I system and cell viability in hepatocytes. view more (2008-10-08)
Researchers shed light on shrinking of chromosomes
A human cell contains an enormous 1.8 metres of DNA partitioned into 46 chromosomes. view more (2007-06-12)
Penn study finds pro-death proteins required to regulate healthy immune function
Researchers at the University of Pennsylvania School of Medicine have found that proteins known to promote cell death are also necessary for the maturation and proliferation of immune cells. view more (2007-08-13)
Birth defects: 8 million annually worldwide
Every year an estimated 8 million children - about 6 percent of total births worldwide - are born with a serious birth defect of genetic or partially genetic origin, according to a new report from the March of Dimes. view more (2006-01-31)
News from Cancer: Risk factors for deadly form of lymphoma
A new study indicates that the incidence of mantle cell lymphoma, an aggressive type of non-Hodgkin's lymphoma, is on the rise, most frequently striking men, Caucasians and older individuals. view more (2008-07-07)
New cell division mechanism discovered
A novel cell division mechanism has been discovered in a microorganism that thrives in hot acid. The finding may also result in insights into key processes in human cells, and in a better understanding of the main evolutionary lineages of life on Earth. view more (2008-10-28)
Crucial Factors in Lymphoma Development and Survival Discovered
Researchers at National Jewish Medical and Research Center have discovered an important factor in the development of B-cell lymphomas, one of the fastest growing forms of cancer. view more (2008-06-24)
Building brains: Mammalian-like neurogenesis in fruit flies
A new way of generating brain cells has been uncovered in Drosophila. The findings, published this week in the online open access journal Neural Development, reveal that this novel mode of neurogenesis is very similar to that seen in mammalian brains, suggesting that key aspects of neural development could be shared by insects and mammals. view more (2008-02-19)
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