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Signaling Pathway Current Events | Signaling Pathway News | 2
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A pathway towards cures for Parkinson`s and cancer Researchers studying the Hedgehog signaling pathway have identified small molecules that could form the foundations of exciting new treatments for Parkinson's disease and certain cancers. New research published in Journal of Biology - the open access journal for exceptional research - has identified small molecules that are able to stimulate or... view more... (2002-11-01)
Why the thumb of the right hand is on the left hand side It is the concentration of a few signaling molecules that determines the fate of individual cells during the early development of organisms. view more (2009-05-22)
Discovery makes brain tumor cells more responsive to radiation Duke University Medical Center researchers have figured out how stem cells in the malignant brain cancer glioma may be better able to resist radiation therapy. view more (2009-12-03)
Endosome-mediated signaling in plants In a paper that will be published online in advance of its July 1st publication date, Drs. Niko Geldner, Joanne Chory and colleagues (The Salk Institute and HHMI) demonstrate that endosomes can function as signaling platforms in plants, as well as in animals. view more (2007-06-19)
Immunity in social amoeba suggests ancient beginnings Finding an immune system in the social amoeba (Dictyostelium discoideum) is not only surprising but it also may prove a clue as to what is necessary for an organism to become multicellular, said the Baylor College of Medicine researcher who led the research that appears today in the journal Science. view more (2007-08-03)
Wnt signalling protein Dishevelled acts in the nucleus, not just in the cytoplasm Researchers have identified that Dishevelled doesn't only function in the cytoplasm and at the cell membrane - it must also pass into the nucleus. A study published today in Journal of Biology reveals that Dishevelled, a key player in the Wnt/beta-catenin signalling pathway, has to be localised in the nucleus to perform a key aspect of its... view more... (2005-02-11)
Plants on steroids: Key missing link discovered Researchers at the Carnegie Institution's Department of Plant Biology have discovered a key missing link in the so-called signaling pathway for plant steroid hormones (brassinosteroids). view more (2009-09-09)
Einstein researchers discover gene mutations linked to longer lifespans Mutations in genes governing an important cell-signaling pathway influence human longevity, scientists at the Albert Einstein College of Medicine of Yeshiva University have found. view more (2008-03-05)
BioImage A/S Signs Research Agreement with Organon BioImage A/S announced today, that it has signed a research agreement with Organon. The agreement outlines the use of BioImage's Redistribution® assays for pathway profiling of selected lead compounds, produced by Organon's discovery projects at its research and development facilities in Oss, the Netherlands. view more (2004-09-07)
Cancer therapy: A role for MAPK inhibitors combined with mTORC1 inhibitors Nearly a decade ago, while it was being tested as an immunosuppressive agent to prevent organ rejection in transplant patients, the drug rapamycin was also discovered to have anti-tumor properties. Since then, several rapamycin analogs known as mTOR (mammalian target of rapamycin) inhibitors have been tested in clinical trials for the treatment of... view more... (2008-08-22)
Insects and mammals share common fat-building pathway, study suggests When it comes to gaining fat, insects and mammals may have something in common, researchers report in the Jan. 11, 2006, Cell Metabolism. view more (2006-01-11)
New method for detection of phosphoproteins reveals regulator of melanoma invasion Scientists have developed a new approach for surveying phosphorylation, a process that is regulated by critical cell signaling pathways and regulates several key cellular signaling events. view more (2009-04-10)
Certain anticancer agents could be harmful to patients with heart disease A set of promising new anticancer agents could have unforeseen risks in individuals with heart disease, suggests research at Washington University School of Medicine in St. Louis. view more (2008-06-24)
Discovery of epigenetic memory during breast cancer According to the researchers, it is becoming increasingly accepted that changes that do not affect the genetic blueprint or DNA sequence, known as the epigenetic landscape, play a major role in defining the properties of normal as well as the cancer cells. view more (2010-01-26)
Lithium and bone healing Researchers have described a novel molecular pathway that may have a critical role in bone healing and have suggested that lithium, which affects this pathway, has the potential to improve fracture healing. view more (2007-07-31)
Ben-Gurion U. researchers identify how stressed fat tissue malfunctions Ben-Gurion University of the Negev (BGU) researchers, in a collaboration with colleagues from the University of Leipzig, Germany, have identified a signaling pathway that is operational in intra-abdominal fat, the fat depot that is most strongly tied to obesity-related morbidity. view more (2009-07-15)
Stanford researchers investigate how plants adapt to climate How many mouths does a plant need in order to survive? The answer changes depending on climate, and some of the decisions are made long before a new leaf sprouts. view more (2008-11-25)
Proteins that stop a major signaling pathway can also generate new proteins Duke University Medical Center researchers have recently discovered that a crucial communications pathway in cells not only stops cells from making proteins, it also makes them go. view more (2008-04-25)
Different signaling pathways of cholangiocarcinoma Cholangiocarcinoma (CCA), a bile duct cancer, is one of the major cancers in Northeast Thailand. This cancer is difficult to diagnose and has high metastatic and mortality rates. view more (2010-03-05)
Protein That Promotes Cancer Cell Growth Identified Scientists at Burnham Institute for Medical Research (Burnham) have found that the Caspase-8 protein, long known to play a major role in promoting programmed cell death (apoptosis), helps relay signals that can cause cancer cells to proliferate, migrate and invade surrounding tissues. view more (2009-07-27)
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