Signaling Pathway Current Events | Signaling Pathway News | 3
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Penn researchers discover initial steps in the development of taste Of the five senses, taste is one of the least understood, but now researchers at the University of Pennsylvania School of Medicine have come one step closer to understanding how the sense of taste develops. view more (2006-12-06)
A crucial role for TGFbeta signaling in congenital eye disorders The lens in the developing eye acts as a TGFbeta signaling center that controls differentiation, survival and formation of multiple eye structures deriving from the neural crest. view more (2005-12-14)
A new take on growth factor signaling in tamoxifen resistance Differences in growth factor (GF) signaling may cause the poor prognosis in some breast cancer cases. A new study, published in the open access journal BMC Medical Genomics, suggests that some estrogen receptor-positive breast cancers respond poorly to tamoxifen because of increased GF signaling. view more (2009-06-24)
Mechanism for regulation of growth and differentiation of adult muscle stem cells is revealed During muscle regeneration, which is a natural response to injury and disease, environmental cues cause adult muscle stem cells (satellite cells) to shift from dormancy to actively building new muscle tissue. view more (2007-12-10)
Study may explain exercise-induced fatigue in muscular dystrophies A University of Iowa study suggests that the prolonged fatigue after mild exercise that occurs in people with many forms of muscular dystrophy is distinct from the inherent muscle weakness caused by the disease. view more (2008-10-27)
Novel link between excessive nutrient levels and insulin resistance For quite some time now, scientists suspected the so-called hexosamine pathway - a small side business of the main sugar processing enterprise inside a cell - to be involved in the development of insulin resistance. But they could never quite put their finger on the underlying mechanism. view more (2008-02-22)
Cytokine resistance contributes to pathology of type 2 diabetes In a study appearing this month in the Journal of Immunology, researchers at the University of Illinois describe how an impaired anti-inflammatory response plays a role in the pathology of type 2 diabetes. view more (2007-06-18)
Model offers new understanding of cell signaling Looking for answers in the bright light of day, rather than the confined beam of a street light at night. That's how University of Michigan researcher Sofia Merajver, M.D., Ph.D., describes the power of a new mathematical model that could have far-reaching impact on how scientists study cellular signaling pathways. view more (2008-03-25)
ISU researcher identifies genetic pathway responsible for much of plant growth Researchers at Iowa State University have discovered a previously unknown pathway in plant cells that regulates plant growth. view more (2009-05-21)
A potential approach to treatment of hepatitis B virus infection Eukaryotic cells employ multiple strategies of checkpoint signaling and DNA repair mechanisms to monitor and repair damaged DNA. view more (2008-09-10)
2 heads are better than 1: 2 dysfunctional DNA repair pathways kill tumor cells Individuals who inherit two mutant copies of any one of about 12 genes that make the proteins of the Fanconi Anemia (FA) pathway develop FA, which is characterized by increased incidence of cancer and bone marrow failure, among other things. view more (2007-04-13)
PINK1 protects from Parkinson's Parkinson disease (PD) is a common neurodegenerative disease characterized by the selective loss of midbrain dopaminergic neurons. view more (2007-06-19)
Newly defined signaling pathway could mean better biofuel sources A newly defined biochemical pathway in plants may provide the scientific tools to design plants that will yield larger quantities of alternative transportation fuels than currently can be produced, according to Purdue University researchers. view more (2008-03-10)
Research uncovers new steps on pathway to enlarged heart Researchers have new insight into the mechanisms that underlie a pathological increase in the size of the heart. The research, published by Cell Press in the October 24th issue of the journal Molecular Cell, may lead to the development of new strategies for managing this extremely common cardiac ailment that often leads to heart failure. view more (2008-10-24)
No-Mow Grass May Be Coming to Your Yard Soon For anyone tethered to a lawnmower, the Holy Grail of horticultural accomplishment would be grass that never grows but is always green. view more (2006-05-08)
New therapeutic target identified for rheumatoid arthritis Researchers at Hospital for Special Surgery have identified a potential new therapeutic target that could be used to treat inflammatory disorders, such as rheumatoid arthritis. view more (2008-11-05)
Study uncovers significant functional differences of novel estrogen receptor Because of these differences, this new estrogen receptor could become an important therapeutic target and may play a further signaling role in other estrogen target tissues, including uterus and prostate tissues. view more (2006-06-09)
New genetic mutations found that may cause cleft lip/palate University of Iowa researchers and collaborators have identified new genetic mutations that likely cause the common form of cleft lip and palate. view more (2007-03-06)
3 newly discovered ERK pathway proteins related to CagA induced disease Cytotoxin-associated gene A protein (CagA) from type I H.pylori has been proved by epidemiological and experimental studies to be closely associated with the H.pylori induced gastric diseases, especially gastric cancer. view more (2008-02-25)
Enzyme's second messenger contributes to cell overgrowth Scientists at the University of California, San Diego (UCSD) School of Medicine have uncovered a novel pathway by which hormones elevated in inflammation, cancer and cell injury act on cells to stimulate their growth. view more (2007-09-27)
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