Signaling Pathway Current Events | Signaling Pathway News | 9
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Crossing paths in plants
On Monday 31 March ecologists will meet with molecular biologists at the University of Southampton for the most novel and broad-ranging scientific session of its kind. They will present findings in Session C5/P3 which show that the biochemical pathways which influence a plant's response to stimuli such as attack, disease or other stresses are not... view more... (2003-03-26)
Executable biology -- Computer science sheds light on animal development
By applying the techniques of computer engineering to a mechanistic diagram describing the development of the Nematode C. elegans, a group of researchers in Switzerland has been able to tease out what laboratory experiments have not - how and when the crucial cross-talk between cellular signaling pathways takes place in order to determine the... view more... (2007-05-18)
Enhancing chemotherapy's efficacy: new agent has synergistic effect with standard drugs
Integrating the use of drugs targeted to specific cancer proteins into current chemotherapy regimens to improve the efficacy of systemic treatment is an important clinical goal at Fox Chase Cancer Center. view more (2007-04-16)
Cancer researchers found a new mechanism potentially explaining evolution of signalling pathways
Cancer researchers at the University of Helsinki, in trying to find a novel tumor suppressor gene, instead found an important evolutionary change that occurred in a key developmental signalling pathway. view more (2006-02-08)
DNA repair in mammal embryos is a matter of timing
Investigators at St. Jude Children's Research Hospital have discovered that the cells of the developing nervous system of the mammalian embryo have an exquisite sense of timing when it comes to fixing broken chromosomes: the cells use one type of repair mechanism during the first half of development and another during the second half. view more (2006-06-20)
Systems properties of insulin signaling revealed
A team of Swedish researchers has characterized novel systems properties of insulin signaling in human fat cells. Their mathematical modeling, described in an article published June 20th in the open-access journal PLoS Computational Biology, provides further insight into energy level maintenance (via the hormone insulin) within our bodies. view more (2008-06-20)
Smoking out the mediators of airway damage caused by pollutants
New insight into how pollution and cigarette smoke damage airways has been provided by Pierangelo Geppetti and colleagues, at the University of Florence, Italy, who studied the effects of such chemicals on guinea pig airways. view more (2008-06-23)
St. Jude finds signaling system that halts the growth of a childhood brain cancer
A discovery by St. Jude Children's Research Hospital scientists suggests a safer way to treat medulloblastoma, a rare but often fatal childhood brain tumor. The group found that one of the brain's signaling pathways inhibits the growth of the highly aggressive cancer cells. view more (2008-03-17)
Findings show insulin - not genes - linked to obesity
Researchers have uncovered new evidence suggesting factors other than genes could cause obesity, finding that genetically identical cells store widely differing amounts of fat depending on subtle variations in how cells process insulin. view more (2009-04-15)
Experimental drug lets B cells live and lymphoma cells die
An investigative drug deprived non-Hodgkin lymphoma cells of their ability to survive too long and multiply too fast, according to an early study published recently in the journal Experimental Hematology. view more (2009-09-22)
New insight into machinery of immune cells' 'tentacles'
Researchers have identified new molecular components of the machinery that regulates formation of the tentacle-like filaments by which immune system T cells grasp other cells. view more (2006-01-10)
Why do people with Down syndrome have less cancer?
Most cancers are rare in people with Down syndrome, whose overall cancer mortality is below 10 percent of that in the general population. view more (2009-05-21)
New brain cells implicated in machinery of cannabinoid signaling
The brain cells called astrocytes, and not just neurons, are sensitive to the substances called cannabinoids-the active chemicals in marijuana. view more (2008-03-27)
How genetic malfunction causes a form of retardation
Researchers have discovered that the genetic malfunction that causes a form of mental retardation called Noonan Syndrome (NS) produces an imbalance in the genesis of two types of cells in the developing embryonic brain. view more (2007-04-19)
Scottsdale Healthcare-TGen clinical trial results signal advances against skin cancer
Analyses of clinical trial results published today in the New England Journal of Medicine (NEJM) shows a potential new investigational therapy for advanced and metastatic basal cell skin cancer. view more (2009-09-03)
MicroRNAs help zebrafish regenerate fins
Biologists have discovered a molecular circuit breaker that controls a zebrafish's remarkable ability to regrow missing fins, according to a new study from Duke University Medical Center. view more (2008-03-17)
Researchers identify cell pathway in colon cancer
For the one in 18 men and women who will be diagnosed with cancer of the colon and rectum during their lifetime and over 150,000 people diagnosed on a yearly basis, today's genetic research news offers some optimism. view more (2007-02-21)
Researchers identify cell pathway in colon cancer
For the one in 18 men and women who will be diagnosed with cancer of the colon and rectum during their lifetime and over 150,000 people diagnosed on a yearly basis, today's genetic research news offers some optimism. view more (2007-02-20)
Genetic tug of war determines sexual differentiation
Whether or not a fertilized mammalian egg ultimately develops into a male or female is determined by the winner of a tug of war between two different genes encoding signaling proteins and the divergent pathways they control. view more (2006-05-24)
Chemical signaling helps regulate sensory map formation in the brain
Researchers from the University of Chicago have uncovered an important mechanism used by the developing brain to pattern nerve connections in the part of the brain that interprets visual signals. view more (2006-01-05)
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