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New brain cells implicated in machinery of cannabinoid signaling
The brain cells called astrocytes, and not just neurons, are sensitive to the substances called cannabinoids-the active chemicals in marijuana.   view more (2008-03-27)

Yale scientists decipher 'wiring pattern' of cell signaling networks
A team of scientists at Yale University has completed the first comprehensive map of the proteins and kinase signaling network that controls how cells of higher organisms operate.   view more (2005-12-01)

Study details hepatitis C ability to block immune system response
Hepatitis C virus (HCV) is a worldwide public health problem. The World Health Organization estimates that 170 million people worldwide are chronically infected and that between 3-4 million are newly infected annually.   view more (2006-05-19)

Study implicates defective synapse generator in onset of Alzheimer's
A new UCLA/Veterans Affairs study implicates defects in the machinery that creates connections between brain cells as responsible for the onset of Alzheimer disease.   view more (2006-01-27)

USC researchers identify alternate pathway that leads to palate development
Researchers at the University Of Southern California School Of Dentistry have uncovered another clue behind the causes of cleft palate and the process that leads to palate formation.   view more (2008-08-11)

Cocaine-induced synaptic plasticity linked to persistent addictive behaviors
The persistent nature of addiction is its most devastating feature. Understanding the mechanism underlying this phenomenon is the key for designing efficient therapy. Two separate studies published by Cell Press is the August 14 issue of the journal Neuron identify specific cocaine-induced changes... view more (2008-08-14)

Oregon researchers discover a mechanism leading to cleft palate
By creating a genetic mutation in zebrafish, University of Oregon scientists say they've discovered a previously unknown mechanism for cleft palate, a common birth defect in humans that has challenged medical professionals for centuries.   view more (2008-02-12)

Scripps research scientists identify new regulatory mechanism for critical protein signaling domain
The study is being published in Science Express, an advanced online edition of the journal Science, on April 5. It will appear in the print version of Science later this spring.   view more (2007-04-06)

Researchers discover mechanism that may enable stem cell-based treatment for eye disorders
In discovering a protein that helps organize the development of the retina, UC Irvine researchers have found a new molecular mechanism that may allow for stem cell-based therapies to treat eye disorders such as retinal degeneration.   view more (2005-06-24)

Glue inside the cell: Ubiquitin builds up an immune response
Ubiquitin is a small protein, which can be attached to other cellular proteins, a process known as ubiquitination. Discoveries in the 1980 th on a key function of ubiquitination in the regulation of protein degradation where awarded with the Nobel Prize for chemistry in 2004.   view more (2007-10-22)

US Patent Granted for Method to Detect Protein Translocations in Cells - Redistribution™
BioImage A/S today announced that it had been granted US 6,518,021, a patent covering the detection of protein translocation in cells using luminophores, such as green fluorescent protein (GFP), fused to the target protein. Redistribution™ - the name coined by the company to describe its... view more (2003-03-03)

Study sheds light on signaling mechanism in stem cells, cancer
UCSF scientists have illuminated a key step in a signaling pathway that helps orchestrate embryonic development.   view more (2005-10-26)

NYU, Scripps finding offers new path for treatment of diabetes
Researchers at New York University and the Scripps Research Institute have discovered a new enzyme, GAPDH, which regulates insulin pathways-a finding that offers a new direction for the treatment of diabetes.   view more (2006-11-28)

Estrogen curbs appetite in same way as the hormone leptin
Estrogen regulates the brain's energy metabolism in the same way as the hormone leptin, leading the way to a viable approach to tackling obesity in people resistant to leptin.   view more (2007-01-04)

Gene therapy inhibits epilepsy in animals
For the first time, researchers have inhibited the development of epilepsy after a brain insult in animals. By using gene therapy to modify signaling pathways in the brain, neurology researchers found that they could significantly reduce the development of epileptic seizures in rats.   view more (2006-11-09)

Embryonic patterning makes the feathers fly
How the chicken got its feathers in the right place is not a Rudyard Kipling "Just So" story, but an illustration of how simple causes can stack up into complicated results. For a chicken, it's the difference between having feathers arranged in spots or stripes. For biologists at the... view more (2006-12-11)

St. Jude finds molecule that could improve cancer vaccines and therapy for other diseases
Investigators at St. Jude Children's Research Hospital have discovered a new signaling molecule that prevents immune responses from running amok and damaging the body.   view more (2007-11-26)

The most important candidate genes for pancreatic stone formation
Stone formation is an important feature of chronic pancreatitis, especially tropical calcific pancreatitis (TCP), where the stones are large in size, highly irregular in shape and cause enormous tissue destruction.   view more (2007-11-14)

Mechanism of nicotine's learning effects explored
While nicotine is highly addictive, researchers have also shown the drug to enhance learning and memory—a property that has launched efforts to develop nicotine-like drugs to treat cognitive deficits in Alzheimer's and Parkinson's diseases, schizophrenia, and attention-deficit/hyperactivity... view more (2007-04-05)

New research identifies gene important for nicotine's effects on the brain
New research identifies an important gene that influences several aspects of nicotine-induced behaviors in the brain. The study, funded by National Institutes of Drug Abuse, was presented today at the American College of Neuropsychopharmacology's Annual Meeting.   view more (2006-12-06)

Einstein researchers discover gene mutations linked to longer lifespans
Mutations in genes governing an important cell-signaling pathway influence human longevity, scientists at the Albert Einstein College of Medicine of Yeshiva University have found.   view more (2008-03-05)

Penn study finds pro-death proteins required to regulate healthy immune function
Researchers at the University of Pennsylvania School of Medicine have found that proteins known to promote cell death are also necessary for the maturation and proliferation of immune cells.   view more (2007-08-13)

More reliable and secure telecommunications via the Internet
Professor Anna Brunström, Karlstad University, is heading a research project that will lead to more reliable and secure telecommunications via the Internet. Reliability is an important aspect when telephony moves over to the Internet, so-called IP-telephony. Today there are three different... view more (2005-03-15)

Mayo Clinic identifies treatment target for liver cancer recurrence and survival
Deadly and difficult to treat, liver cancer has long resisted attempts by researchers to develop ways to prolong life and prevent recurrence.   view more (2008-04-11)

Overexcited neurons not good for cell health
Neurotransmitters have consequences. They initiate events that are critical to a healthy life, giving us the ability to move, to talk, to breathe, to think. But that's if the neurotransmitters are getting it right and sending proper signals downstream to muscle cells, neurons or other cells.   view more (2007-12-18)
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