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How does a zebrafish grow a new tail?
If a zebrafish loses a chunk of its tail fin, it'll grow back within a week. Like lizards, newts, and frogs, a zebrafish can replace surprisingly complex body parts. A tail fin, for example, has many different types of cells and is a very intricate structure. It is the fish version of an arm or leg.   view more (2006-12-27)

Research elucidates mechanism by which gene expression may be altered in drug addiction
Dr. Judith A. Potashkin, Ph.D. and her colleagues at Rosalind Franklin University of Medicine and Science recently completed a study investigating one of the changes in gene expression that occurs when individuals take addictive drugs.   view more (2007-09-05)

UCLA physicists report advance toward nanotechy approach to protein engineering
UCLA physicists report a significant step toward a new approach to protein engineering in the June 8 online edition, and in the July print issue, of the Journal of the American Chemical Society.   view more (2006-06-12)

Weight control protein may yield antiobesity drugs
A weight control protein with a key role in the brain's ability to monitor body fat content may yield new approaches for treating obesity and type 2 diabetes, according to a new report in the August issue of Cell Metabolism.   view more (2005-08-17)

Brain size may depend upon how neural cells are cleaved
Howard Hughes Medical Institute researchers have discovered a novel way in which the brain size of developing mammals may be regulated. They have identified a signaling pathway that controls the orientation in which dividing neural progenitor cells are cleaved during development.   view more (2005-07-15)

Analysis of alcoholics' brains suggests treatment target
An analysis of brain tissue samples from chronic alcoholics reveals changes that occur at the molecular level in alcohol abuse - and suggests a potential treatment target, according to researchers from Wake Forest University School of Medicine.   view more (2008-05-05)

Certain anticancer agents could be harmful to patients with heart disease
A set of promising new anticancer agents could have unforeseen risks in individuals with heart disease, suggests research at Washington University School of Medicine in St. Louis.   view more (2008-06-24)

Discovery of new protein could provide new understanding of male fertility
Scientists have discovered a new enzyme involved in the degradation of proteins inside cells, a process that helps eliminate or recycle proteins that are no longer needed.   view more (2007-08-03)

Insects and mammals share common fat-building pathway, study suggests
When it comes to gaining fat, insects and mammals may have something in common, researchers report in the Jan. 11, 2006, Cell Metabolism.   view more (2006-01-11)

Neural Stem Cells Are Long-Lived
New studies in mice have shown that immature stem cells that proliferate to form brain tissues can function for at least a year - most of the life span of a mouse - and give rise to multiple types of neural cells, not just neurons.   view more (2005-10-06)

One protein, two channels: Scientists explain mechanism in aquaporins
Using computer simulations and experimental results, researchers at the University of Illinois at Urbana-Champaign and the University of Arizona have identified a key component of the gating mechanism in aquaporins that controls both the passage of water and the conduction of ions.   view more (2006-09-22)

Researcher discovers pathway plants use to fight back against pathogens
Plants are not only smart, but they also wage a good fight, according to a University of Missouri biochemist. Previous studies have shown that plants can sense attacks by pathogens and activate their defenses.   view more (2008-04-01)

Depression linked to previously unknown dopamine regulator
Researchers from Harvard Medical School have found a molecule that is unexpectedly involved in dopamine signaling, and in a manner that supports the potential of dopamine as an alternative target for treating depression.   view more (2005-07-29)

New methods identify and manipulate 'newborn' cells in animal model of Parkinson's disease
When cells in the brain are lost through disease or injury, neighboring cells begin to divide and multiply, but only a few areas in the brain are able to produce new neurons.   view more (2008-09-04)

Scythe balances life and death during development
A protein called Scythe determines which cells live and which die during the growth and development of the mammalian embryo, according to investigators at St. Jude Children's Research Hospital.   view more (2005-12-13)

Nobelist discovers antidepressant protein in mouse brain
A protein that seems to be pivotal in lifting depression has been discovered by a Nobel Laureate researcher funded by the National Institutes of Health's National Institute of Mental Health (NIMH).   view more (2006-01-06)

University to develop new therapeutics for cancer
Dr Roger Barraclough, from the School of Biological Sciences, is working on a new protein which causes some cancer cells to spread around the body. This protein is being developed to assist in improving the management of breast cancer.   view more (2006-07-28)

Cell signaling discovery yields heart disease clues
A pulsing heart cell is giving Oregon Health & Science University researchers insight into how it sends and receives signals, and that's providing clues into how heart disease and other disorders develop.   view more (2005-09-23)

Cell signaling discovery yields heart disease clues
A pulsing heart cell is giving Oregon Health & Science University researchers insight into how it sends and receives signals, and that's providing clues into how heart disease and other disorders develop.   view more (2005-09-26)

Stanford researchers find culprit in aging muscles that heal poorly
Communication is critical. Garbled in, garbled out, so to (mis-)speak. Workers who get incomplete instructions produce an incomplete product, and that's exactly what happens with the stem cells in our aging muscles.   view more (2007-08-10)

NYU scientists identify critical protein complex in formation of cell cilia
An international team led by NYU Cancer Institute have identified a protein complex that regulates the formation of cilia, which are found on virtually all mature human cells and are essential to normal cell function.   view more (2008-08-20)

Blocking protein kills prostate cancer cells, inhibits tumor growth, Jefferson scientists find
Researchers at Jefferson's Kimmel Cancer Center in Philadelphia have shown that they can effectively kill prostate cancer cells in both the laboratory and in experimental animal models by blocking a signaling protein that is key to the cancer's growth.   view more (2008-02-28)

UCSD study reveals the regulatory mechanism of key enzyme
Research conducted at the University of California, San Diego (UCSD) School of Medicine has shed new light on the structure and function of one of the key proteins in all mammalian cells, protein kinase A (PKA), an enzyme which plays an essential role in memory formation, communication between... view more (2007-09-21)

Model offers new understanding of cell signaling
Looking for answers in the bright light of day, rather than the confined beam of a street light at night. That's how University of Michigan researcher Sofia Merajver, M.D., Ph.D., describes the power of a new mathematical model that could have far-reaching impact on how scientists study cellular... view more (2008-03-25)

Gene discovery may shed light on kidney disease
In a finding that may have broader implications for understanding kidney disorders, genetics researchers at The Children's Hospital of Philadelphia have identified a second gene that gives rise to Alagille syndrome, a genetic developmental disease that affects multiple organs.   view more (2006-08-01)
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