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Natural born killers -- how the body's frontline immune cells decide which cells to destroy
The mechanism used by 'Natural Killer' immune cells in the human body to distinguish between diseased cells, which they are meant to destroy, and normal cells, which they are meant to leave alone, is revealed in new detail in research. view more (2009-07-28)
Studies suggest new brain protein may help in treating schizophrenia, insomnia and anxiety
A small protein in the brain that has only recently been discovered and, paradoxically, induces both profound wakefulness and a less anxious state, may represent a novel target for the treatment of psychotic behavior and schizophrenia. view more (2006-06-23)
What emotional memories are made of
Both extensive psychological research and personal experiences confirm that events that happen during heightened states of emotion such as fear, anger and joy are far more memorable than less dramatic occurrences. view more (2007-10-05)
Flowers' fragrance diminished by air pollution, University of Virginia study indicates
Air pollution from power plants and automobiles is destroying the fragrance of flowers and thereby inhibiting the ability of pollinating insects to follow scent trails to their source, a new University of Virginia study indicates. view more (2008-04-11)
UT Southwestern researchers identify molecule that helps the sleep-deprived to mentally rebound
Sleep experts know that the mental clarity lost because of a few sleepless nights can often be restored with a good night's rest. Now, UT Southwestern Medical Center researchers have identified a key molecular mechanism that regulates the brain's ability to mentally compensate for sleep deprivation. view more (2009-02-24)
What is the function of NOD2 in colonic epithelial cells?
NOD2 is a cytosolic pattern recognition receptor similar in structure and function to Toll like receptors (TLRs). It can recognize and respond to a component found in the cell wall of bacteria, muramyl dipeptide (MDP), and has been shown to play an important role in the innate immune response of macrophages to bacterial infections. view more (2008-10-23)
Dartmouth researchers find that low doses of arsenic have broad impact on hormone activity
Dartmouth Medical School investigators are learning more about how low doses of arsenic, such as the levels found in drinking water in many areas of the United States, affect human physiology. view more (2006-12-05)
Microbes start immune response by sneaking inside cells
Immune cells that are the body's front-line defense don't necessarily rest quietly until invading bacteria lock onto receptors on their outside skins and rouse them to action, as previously thought. In a new paper, University of Michigan scientists describe their findings that bacteria can barge inside these guard cells and independently initiate... view more... (2007-04-16)
Jefferson Scientists Identify Gene Mutation Potentially Involved in Breast Cancer Initiation
Researchers at Jefferson Medical College and the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia and at the Albert Einstein College of Medicine in New York have found evidence suggesting that a mutation in a gene that normally helps block the formation of breast tumors could play a role in the initiation of a major form of... view more... (2006-06-01)
A new idea for how anti-aging products delay ripening of fruit and wilting of flowers
When plants encounter ethylene, a gas they also produce naturally as a hormone, the result is softening and ripening in the case of fruit, and wilting and fading in the case of flowers - all of which ethylene promotes. view more (2008-05-05)
Joslin researchers uncover potential role of leptin in diabetes
A new Joslin-led study has shown that leptin, a hormone known mainly for regulating appetite control and energy metabolism, plays a major role in islet cell growth and insulin secretion. view more (2007-10-02)
Does Stimulant Treatment for ADHD Increase Risk of Drug Abuse?
Parents, doctors, and others have wondered whether common treatments for attention-deficit hyperactivity disorder (ADHD) inadvertently predispose adolescents to future drug abuse. view more (2007-06-19)
Proteins anchor memories in our brain
A University of Utah study suggests that memories are held in our brains because certain proteins serve as anchors, holding other proteins in place to strengthen synapses, which are connections between nerve cells. view more (2006-11-22)
DACH1 a key protein for tumor suppression in ER+ breast cancer
Researchers from the Kimmel Cancer Center at Jefferson have identified a protein relationship that may be an ideal treatment target for ER+ breast cancer. view more (2009-07-15)
Drugs targeted at muscle cells can be of use in the treatment of diabetes patients with insulin resistance
Type 2 diabetes is a clinical disease characterised by disruption to the metabolism of glucose and lipids as well as to the production of and physiological reactions to insulin. These disruptions are partly due to a reduced absorption of glucose in the cells that form the body's fat and muscle tissue. Now scientists at Karolinska Institutet have... view more... (2005-04-18)
Agent Protects Parkinson's Neurons from Rotenone Toxicity
Researchers at the University at Buffalo affiliated with the New York State Center of Excellence in Bioinformatics and Life Sciences have identified a novel agent that can protect neurons involved in Parkinson's disease from being destroyed by the pesticide rotenone. view more (2006-04-19)
Breast stem cells have features similar to 'basal' tumors
The most aggressive form of breast cancer may originate from breast stem cells that have undergone genetic mishaps. view more (2006-07-20)
New approach for growing bone comes from Duke preclinical research
The natural cycle of building bone to maintain skeletal strength and then breaking it down for the body's calcium needs is delicately balanced, but diseases like osteoporosis break down too much bone without adequate bone replacement, leading to bone fractures. view more (2009-10-08)
UVa Scientists Hot on Trail of Therapies for Deadly Lung Failure
Researchers at the University of Virginia Health System have identified a molecular target, or receptor, for potential drugs to treat acute respiratory distress syndrome (ARDS), a sudden and life-threatening failure of the lung. view more (2006-02-22)
Scripps research team defines new painkilling chemical pathway
Marijuana kills pain by activating a set of proteins known as cannabinoid receptors, which can also regulate appetite, inflammation, and memory. view more (2008-11-24)
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