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New therapeutic target identified for rheumatoid arthritis
Researchers at Hospital for Special Surgery have identified a potential new therapeutic target that could be used to treat inflammatory disorders, such as rheumatoid arthritis. view more (2008-11-05)
Study finds possible connection between marijuana abuse and stroke or heart attacks
Long-term harmful effects of marijuana (MJ) include risk for heart attacks and strokes in addition to impaired learning and memory. The active chemical in MJ called delta-9-tetrahyrdocannabinol (THC) is believed to exert these effects by binding to cannabinoid (CB) receptors located on several cell types in various organs. view more (2008-05-13)
Bisexual fruit flies show new role for neurochemical
Fruit flies' ability to discern one sex from another may depend on the number of receptors on the surface of nerve cells, and the number of receptors is controlled by levels of a ubiquitous brain chemical, University of Illinois at Chicago researchers have found. view more (2007-01-04)
Designing probiotics that ambush gut pathogens
Researchers in Australia are developing diversionary tactics to fool disease-causing bacteria in the gut. view more (2009-09-08)
PET imaging confirms link between receptor levels and cocaine abuse
Using positron emission tomography (PET), researchers have established a firm connection between a particular brain chemistry trait and the tendency of an individual to abuse cocaine and possibly become addicted, suggesting potential treatment options. view more (2006-07-12)
Red alert! How disease disables tomato plant's 'intruder alarm'
How a bacterium overcomes a tomato plant's defences and causes disease, by sneakily disabling the plant's intruder detection systems, is revealed in new research out today (4 December) in Current Biology. view more (2008-12-05)
Scientists find hormone activity explains adolescent mood swings
The "raging hormones" of puberty are known to produce mood swings and stress for most teenagers, making it difficult to cope with this period of life. Until now, the specific causes of pubertal anxiety have not been identified, making it harder to understand and treat adolescent angst. view more (2007-03-12)
Chinese acupuncture affects brain's ability to regulate pain, UM study shows
Acupuncture has been used in East-Asian medicine for thousands of years to treat pain, possibly by activating the body's natural painkillers. But how it works at the cellular level is largely unknown. view more (2009-08-10)
Nitric oxide: Key to cardiovascular and pulmonary function and drug effectiveness
A naturally occurring molecule in the body appears to control whether certain medications, such as beta adrenergic receptor agonists used in acute heart failure or in inhalers for asthma, lose their effectiveness over time. view more (2007-05-04)
Endosome-mediated signaling in plants
In a paper that will be published online in advance of its July 1st publication date, Drs. Niko Geldner, Joanne Chory and colleagues (The Salk Institute and HHMI) demonstrate that endosomes can function as signaling platforms in plants, as well as in animals. view more (2007-06-19)
Irritating smells alert special cells, NIH-funded study finds
If you cook, you know. Chop an onion and you risk crying over your cutting board as a burning sensation overwhelms your eyes and nose. Scientists do not know why certain chemical odors, like onion, ammonia and paint thinner, are so highly irritating, but new research in mice has uncovered an unexpected role for specific nasal cavity cells. view more (2008-03-04)
Potential new pain killer drug developed by scientists at Leicester and Italy
A potential new pain-killing drug developed by medical scientists at the University of Leicester and Ferrara in Italy is to be discussed at a public lecture on 20th March. view more (2007-03-16)
Glycoprotein hormone receptors
We have aspired at understanding and further dissecting the molecular mechanism of activation of the Glycoprotein hormone receptors (GpHr), members of the G protein coupled receptor (GPCR) superfamily. view more (2006-01-17)
Scientists discover how common vaccine booster works
In an online paper in the journal Nature, Yale University researchers funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, explain how a common ingredient in many vaccines stimulates and interacts with the immune system to help provide protection against infectious diseases. view more (2008-05-22)
Overproducing leptin receptors in fat cells may be key to halting weight gain
A new study by researchers at UT Southwestern Medical Center suggests that when fat cells increase in size - as they do during the development of obesity - the cells progressively lose receptors for the hormone leptin, a powerful stimulus for fat burning. view more (2005-12-01)
Could hormones explain gender differences in neurological disease?
Neurological diseases including Parkinson's, Tourette's, attention deficit hyperactivity disorder (ADHD), Alzheimer's, and schizophrenia are all associated with alterations in dopamine-driven function involving the dopamine transporter (DAT). view more (2009-06-16)
Opioids and cannabinoids influence mobility of spermatozoids
A PhD thesis from the University of the Basque Country has concluded that there are opioid and cannabinoid receptors in human sperm and that these influence the mobility of spermatozoid. view more (2008-06-23)
Targeting helpers of heat shock proteins could help treat cancer, cardiovascular disease
Dissecting how heat shock protein 90 gets steroid receptors into shape to use hormones like estrogen and testosterone could lead to targeted therapies for hormone-driven cancers, such as breast and prostate, that need them as well, Medical College of Georgia researchers say. view more (2009-06-23)
Researchers discover stem cell 'guide' that may be key for targeting neural stem cell treatments
UC Irvine School of Medicine researchers have discovered how new neurons born from endogenous neural stem cells are sent to regions of the brain where they can replace old and dying cells, a finding that suggests how stem cell therapies can be specifically targeted to brain regions affected by neurodegenerative diseases or by stroke. view more (2005-06-24)
MIT finds key to avian flu in humans
MIT researchers have uncovered a critical difference between flu viruses that infect birds and humans, a discovery that could help scientists monitor the evolution of avian flu strains and aid in the development of vaccines against a deadly flu pandemic. view more (2008-01-07)
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