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Breast cancer : Discovery of a new tumor marker
At the Curie Institute in Paris, CNRS researchers have discovered a new proliferation marker : the CAF-1 complex. Since deregulated cell proliferation is one of the most characteristic features of tumor cells, this discovery represents a breakthrough in the cancer field. The researchers from the Curie Institute have already validated the use of... view more... (2004-03-30)
Earth's core rotates faster than its crust, scientists say
Scientists have ended a 9-year-old debate by proving that Earth's core rotates faster than its surface, by about 0.3 to 0.5 degree per year. view more (2005-08-26)
A new therapeutic option for human hepatocyte cancer
p53-impaired tumors may be particularly suitable to parvovirus H-1-induced therapy. Although the p53 deficiency in tumors may induce resistance to chemotherapeutic agents, this will not affect the tumor cell susceptibility to H-1 PV-induced oncolytic infections. view more (2008-09-24)
NMR researchers unlock hydrogen's secrets to spot polymorphism in pharmaceuticals
Researchers at the University of Warwick and Astra Zeneca have found a new way to use solid-state NMR equipment to crack the secrets of hydrogen atoms and thus spot unwanted polymorphs in pharmaceuticals. view more (2007-10-18)
Massive necrosis after trans-catheter treatment is more common in the presence of tumor capsule
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Prognosis of patients with HCC complicating cirrhosis mainly depends on the tumor growth, progression of the underlying liver disease and the effectiveness of antitumoral treatment. view more (2007-11-26)
Microchip-based device can detect rare tumor cells in bloodstream
A team of investigators from the Massachusetts General Hospital (MGH) Biomicroelectromechanical Systems (BioMEMS) Resource Center and the MGH Cancer Center has developed a microchip-based device that can isolate, enumerate and analyze circulating tumor cells (CTCs) from a blood sample. view more (2007-12-20)
Circulating blood cells are important predictors of cancer spread in children
Endothelial progenitor cells may play a role in the start and progression of metastatic disease in children with cancer. view more (2009-07-15)
Second low-oxygen pathway hints at cancer, cardiovascular disease physiology
Researchers at the University of Pennsylvania School of Medicine have identified a second molecular pathway that promotes cell survival in low-oxygen conditions. view more (2006-02-17)
Production of spherical beads with the JetCutter
A major problem in particle production technology is the large scale production of uniform beads from viscous fluids. Producing such beads is of interest in various industrial sectors, e.g. chemical, pharmaceutical and food industry, agriculture, biotechnology. The JetCutter is a new and simple technology for bead production that meets the... view more... (2003-11-03)
Post-pregnancy events promote breast tumor metastasis
Changes in the tissue environment of the breast that occur after pregnancy promote the metastasis of breast tumor cells. view more (2006-02-03)
Mayo Clinic researchers discover and manipulate molecular interplay that moves cancer cells
Based on research that reveals new insight into mechanisms that allow invasive tumor cells to move, researchers at the Mayo Clinic campus in Florida have a new understanding about how to stop cancer from spreading. A cancer that spreads elsewhere in the body, known as metastasis, is the process that most often leads to death from the disease. view more (2009-03-30)
Tulane pioneers novel ovarian cancer treatment
The Tulane University Section of Hematology and Medical Oncology is investigating a novel treatment for ovarian cancer by using intravenous Ontak to deplete harmful cells that inhibit the body's natural immune response to fight cancer. Ovarian cancer is the fifth leading cancer killer of women in the United States. view more (2005-07-18)
Inhibiting cell process may give cancer drug a boost
A molecule that interferes with the internal scaffolding that shapes the cell may kill cancer cells, retard the growth of tumors and give a boost to a common chemotherapy drug. view more (2006-05-04)
Study identifies new tumor suppressor
A protein called HLJ1 may work as a novel tumor suppressor in non-small-cell lung carcinoma. view more (2006-06-21)
Nobel Laureates published with IoPP
Institute of Physics Publishing (IoPP) is proud to note that five of the 2003 Nobel Prize winners have published important works with its journals. Many of these have been key papers, which have contributed to their success today. Sir Peter Mansfield, joint winner of the Nobel Prize in Medicine, has published a total of 25 papers relating to... view more... (2003-10-07)
New insights into the regulation of PTEN tumor suppression function
The PTEN tumor suppressor gene controls numerous biological processes including cell proliferation, cell growth and death. But PTEN is frequently lost or mutated; in fact, alteration of the gene is so common among various types of human cancer that PTEN has become one of the most frequently mutated of all tumor suppressors. view more (2008-08-21)
Fly with brain tumor may shed light on cancer causing genes
A study showing how the expression of genes changes when the brain tissue of fruit flies becomes cancerous is published this week in BMC Genomics. As the function of many of these genes is conserved across evolution, the researchers expect their results will help us to understand why human brain tumors develop. The causes of brain tumor... view more... (2004-04-14)
Are tumors causing stricture of bile duct always malignant?
The benign biliary tract tumor is rarely found in clinical practice. One case of bile duct adenomyoma was recently reported in the January 28 issue of the World Journal of Gastroenterology. view more (2008-02-22)
Bone drug could help prevent the spread of breast cancer
Maintaining bone density could be a key to decreasing the spread of cancer in women with locally advanced breast cancer, according to research at Washington University School of Medicine in St. Louis. view more (2008-05-19)
MicroRNA-mediated metastasis suppression
Metastases are responsible for over 90% of cancer deaths. In the upcoming issue of G&D, Dr. Robert Weinberg (MIT) and colleagues lend molecular insight into how microRNAs suppress tumor metastasis. view more (2009-10-29)
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