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Protein misprediction uncovered by new technique
A new bioinformatics tool is capable of identifying and correcting abnormal, incomplete and mispredicted protein annotations in public databases. view more (2008-08-27)
Researchers induce HIV-neutralizing antibodies that recognize HIV-1 envelope protein, lipids
For the first time, researchers have experimentally induced antibodies that neutralize HIV-1 and simultaneously recognize both HIV-1 envelope protein and lipids. view more (2009-09-02)
The Nobel Prize in Chemistry 2004
The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry for 2004 "for the discovery of ubiquitin-mediated protein degradation" jointly to view more (2004-10-06)
Water is 'designer fluid' that helps proteins change shape, scientists say
Ubiquitous on Earth, water also has been found in comets, on Mars and in molecular clouds in interstellar space. Now, scientists say this common fluid is not as well understood as we thought. view more (2008-08-07)
Neural development protein disproved as marker for schizophrenia
The results of a study published today in the open access journal BMC Psychiatry contradict previous findings and show that Oct-6, a protein involved in neurodevelopment, is normally expressed in the adult brain and cannot be used to identify patients with schizophrenia. view more (2005-10-24)
Study reveals mass migration of mormon crickets driven by hunger, fear
An international team of researchers, including Kent State University professor Dr. Patrick D. Lorch, have revealed the motivating factors behind the seasonal mass migration of Mormon crickets in western North America. view more (2006-03-03)
Scientists unlock secret of what makes plants flower
The study reveals the likely mechanism by which the Arabidopsis plant flowers in response to changes in day length. Earlier research had shown that plants' leaves perceived seasonal changes in day length, which triggers a long-distance signal to travel through the plant's vascular system from the leaf to the shoot apex, where flowering is induced. view more (2007-04-20)
A protein interaction map for a better insight in cancer development
With the completion of the genome sequence of a number of organisms, analysis of the gene products, the proteins, is the on-going challenge. view more (2005-02-28)
Linking 2 molecular pieces of the Alzheimer's puzzle
Researchers have uncovered a biological link between the protein whose mutation causes early-onset Alzheimer's disease (AD) and a gene variant linked to late-onset AD. The researchers said their finding could lead to new approaches to treating AD. view more (2007-10-04)
Workman Lab characterizes novel regulator of chromosome function
The Stowers Institute's Workman Lab has shed new light on a novel histone acetyltransferase protein complex called ATAC. Acetyltransferases are enzymes that introduce a new acetyl functional group into histone proteins, a process by which all chromosome functions are controlled. view more (2008-03-11)
Compound reveals new link between signaling protein and cell migration
University of Illinois at Chicago researchers report that a protein that regulates key signaling pathways in cells also plays a role in controlling the active movement or migration of cells. view more (2005-09-26)
Scientists on track for early diagnosis of neurological diseases
Possible treatments for fatal neurodegenerative diseases such as CJD, Alzheimer's, Parkinson's could result from University of Edinburgh research to find out how specific proteins cause deterioration in brain function. The scientists have discovered for the first time that protein 14-3-3 plays a key role in the development of certain brain... view more... (2003-07-01)
HIV isolate from Kenya provides clues for vaccine design
Two simple changes in its outer envelope protein could render the AIDS virus vulnerable to attack by the immune system, according to research from Kenya and the Fred Hutchinson Cancer Research Center published in PLoS Medicine. view more (2008-01-03)
Viral oncoprotein inactivation of p53
A group of scientists led by USC researcher Dr. Xiaojiang Chen lend structural insight into tumor suppressor inactivation by a viral oncoprotein. view more (2006-09-01)
Kids still not drinking enough milk
American children are drinking too little milk and what they are consuming is too high in fat, according to a Penn State study. view more (2007-10-05)
Protein may predict heart attack and early death, not stroke
People with high levels of a protein called C-reactive protein (CRP), a marker for inflammation in the blood, may be at higher risk for heart attack and death but not stroke, according to a study published in the October 20, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology. view more (2009-10-20)
Zeroing in on Alzheimer's
Hereditary Alzheimer's disease has been shown to be the result of mutations in certain specific genes. Other cases of Alzheimer's are also assumed to be traceable to the influence of a number of still unidentified genes. It is probable that these genes are located in a large area on chromosome 10q, which contains more than 100 genes. Working with... view more... (2003-09-25)
Protein identified that turns off HIV-fighting T cells
In HIV-infected patients the body's immune system is unable to fight off the virus. A new study to be published online on November 10th in the Journal of Experimental Medicine shows that T cells in HIV-infected individuals express a protein called TIM-3, which inactivates their virus killing capacity. view more (2008-11-10)
Researchers report the cloning of a key group of human genes, the protein kinases
Although the human genome has been sequenced, research into mechanism of action of genes has been hampered by the fact that most human genes have not been isolated. This is true for even the most common class of cancer-associated genes, the protein kinases, which mediate the majority of signaling events in cells by phosphorylating and modulating... view more... (2008-05-05)
NIST trumps the clumps: Making biologic drugs safer
Scientists at the National Institute of Standards and Technology (NIST) have developed a technique to measure the formation of clumps of proteins in protein-based pharmaceuticals. view more (2008-07-24)
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