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CSHL shows correcting rna splicing may help treat spinal muscular atrophy
RNA splicing antisense technology studied at Cold Spring Harbor Laboratory (CSHL) effectively corrected an mRNA splicing defect found in spinal muscular atrophy (SMA) patients, and is now ready to be tested in mouse models.   view more (2007-03-13)

Subtypes of ependymomas arise from rare stem cells in the nervous system
Brain tumors called ependymomas that occur in different parts of the central nervous system appear to arise from subpopulations of stem cells called radial glia cells (RGCs).   view more (2005-10-18)

Inert gas may help stop damaged nerve cells from dying
Scientists from Imperial College London have discovered that xenon gas could help in protecting damaged nerve cells. The research, published today in Anesthesiology, shows that xenon, an inert gas, acts as a neuroprotectant, helping to protect damaged nerve cells from dying. Based upon... view more (2002-05-29)

Combining multiple treatments improves multiple sclerosis therapy
Multiple sclerosis (MS) is an inflammatory autoimmune disease of the central nervous system (CNS) in which white blood cells known as lymphocytes attack the myelin insulation on nerves in the spinal cord and brain.   view more (2006-03-17)

Gene therapy improves gemcitabine effects in experimental glioma model
ttempts to improve the chemotherapeutic efficacy and radiotherapy-sensitivity of the anticancer agent, gemcitabine, using gene therapy have yielded interesting results in preclinical glioma models presented at the 13th European Cancer Conference (ECCO).   view more (2005-11-01)

Ume'å physiologists describe a new principle for information coding in the nervous system
How does the nervous system code, transmit, and process the information that steers our behaviour? Ronald S. Johansson's research team at Ume'å University in Sweden is now publishing its discovery of a new principle for this. The prevailing view is that information is coded and transmitted... view more (2004-01-20)

U of M performs first systemic therapy for fatal childhood disease
University of Minnesota Children's Hospital, Fairview physicians have performed the first bone marrow and cord blood transplant to treat recessive dystrophic epidermolysis bullosa (RDEB).   view more (2007-11-05)

Treatment extends survival in mouse model of spinal muscular atrophy
Drug therapy can extend survival and improve movement in a mouse model of spinal muscular atrophy (SMA), new research shows. The study, carried out at the NIH's National Institute of Neurological Disorders and Stroke (NINDS), suggests that similar drugs might one day be useful for treating human... view more (2007-02-23)

BSE TRANSMITTED THROUGH BLOOD TRANSFUSIONS IN SHEEP
In this weeks' issue of THE LANCET, scientists from the UK report preliminary data from an ongoing experiment which suggests that bovine spongiform encephalopathy (BSE), which is caused by the same agent as variant Creutzfeldt-Jakob disease (vCJD), can be passed on by blood transfusions before... view more (2000-09-14)

Role for microRNAs in limb regeneration
In the March 15th issue of G&D, Dr. Kenneth Poss (Duke University Medical Center) and colleagues reveal that microRNA depletion is a necessary step in tissue regeneration - a discovery with interesting implications for their use in regenerative medicine.   view more (2008-03-17)

Corticosteroids associated with poor outcomes, death in the trauma intensive care unit
Patients in the trauma intensive care unit who receive corticosteroids may have more infections, longer stays in intensive care or on a ventilator and a higher death rate than those who do not.   view more (2006-02-21)

Gene changes linked to deficient immune suppression in MS
Oregon Health & Science University researchers have measured genetic changes reflecting a drop in the body's ability to suppress inflammatory cells that attack nerve fibers and promote progression of multiple sclerosis.   view more (2005-06-27)

UT Southwestern urologist uses Botox to treat debilitating condition
Eight years ago, Lynette Kunz suffered a severe spinal cord injury that left her a quadriplegic and sufferer of involuntary bladder contractions. The condition constantly interfered with her daily life.   view more (2007-12-05)

Researchers identify the cells and receptor for sensing sour taste
In the last seven years, Howard Hughes Medical Institute researcher Charles S. Zuker and Nicholas J.P. Ryba at the National Institutes of Health have worked together to identify the cells, receptors and signaling mechanisms for three of the five tastes humans can sense - sweet, bitter, and umami... view more (2006-08-24)

Scientists produce neurons from human skin
Scientists from Université Laval's Faculty of Medicine have succeeded in producing neurons in vitro using stem cells extracted from adult human skin.   view more (2007-02-23)

Neuroscientists explain inner workings of critical pain pathway
Whether they're fighting postoperative soreness or relieving chronic discomfort from conditions such as cancer, morphine and other opioids are powerful weapons against pain. Now, in research published online in Nature Neuroscience, Brown University scientists give one reason why these painkillers... view more (2007-02-16)

Standing up to paraplegia with gene therapy
Elena Rugarli and colleagues from the National Neurological Institute in Milan have used gene therapy to save sensory and skeletal muscle nerve fibers from degeneration in mice with hereditary spastic paraplegia (HSP).   view more (2005-12-16)

First-born babies' higher asthma and allergy rates due to pregnancy conditions
First-born children are at higher risk of developing asthma and allergy because of different conditions they experience in the uterus, according to new research from the Isle of Wight in the United Kingdom, which will be presented at the American Thoracic Society's 2008 International Conference in... view more (2008-05-20)

New treatment option breaks Leukemia's resistance to chemotherapy, radiation therapy
German researchers set out to outwit cancer tumor cells that have become resistant to chemotherapy or radiation therapy and ended up expanding therapeutic applications of radionuclides in fighting leukemia.   view more (2006-06-05)

Mount Sinai Hospital researcher develops Canada's first embryonic stem cell lines
A senior scientist at Mount Sinai Hospital has developed Canada's first two human embryonic stem cell lines, giving researchers across the country new potential and hope for eventually discovering treatments and cures for many chronic and fatal diseases.   view more (2005-06-08)

Minimally invasive device shows promise in treating female urinary incontinence
A minimally invasive device for treating recurrent stress urinary incontinence in women has been shown to be safe and effective in early clinical trials and is now under review by the U.S. Food and Drug Administration (FDA).   view more (2007-05-23)

Protein key to neuro-regeneration
Researchers at the Peninsula Medical School in the South West of England, University College London, the San Raffaele Scientific Institute in Milan and Cancer Research UK, have for the first time identified a protein that is key to the regeneration of damage in the peripheral nervous system and... view more (2008-05-21)

Updated rates of common US neurological disorders
In an up-to-date review of most of the common neurological disorders in the United States published in the January 30, 2007, issue of Neurology®, the scientific journal of the American Academy of Neurology, researchers reviewed studies from nearly 500 articles published between 1990 and 2005 to... view more (2007-01-30)

Oxford Biomedica Obtains Further Fundamental Patent For Lentiviral Gene Therapy Technology
Oxford BioMedica plc announced today that it has received allowance from the US Patent Office for a further patent covering its proprietary LentiVector technology. This additional patent compliments the US patent 6,312,682 issued in November 2001 and both include broad composition of matter claims... view more (2003-08-13)

Stem cell research produces a key discovery for Fragile X Syndrome
An important finding has been made by McMaster researchers about Fragile X Syndrome (FXS), a sex-linked genetic disorder that affects approximately one in 4,000 males and one in 6,000 females.   view more (2007-09-11)

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