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Penn researchers gain new insights on spinal muscular atrophy
Researchers from the University of Pennsylvania School of Medicine discovered that the effect of a protein deficiency, which is the basis of the neuromuscular disease spinal muscular atrophy (SMA), is not restricted to motor nerve cells, suggesting that SMA is a more general disorder.   view more (2008-05-30)

Scientists discover possible new treatment for genetic diseases
Scientists from Imperial College London, the University of Leicester, and Hammersmith Hospital have found a way to stop certain types of genetic diseases from occurring by modifying the way DNA is turned into proteins. The research published in this month's Proceedings of the National Academy of... view more (2003-03-14)

CSHL shows correcting rna splicing may help treat spinal muscular atrophy
RNA splicing antisense technology studied at Cold Spring Harbor Laboratory (CSHL) effectively corrected an mRNA splicing defect found in spinal muscular atrophy (SMA) patients, and is now ready to be tested in mouse models.   view more (2007-03-13)

A glimmer of hope in the struggle against neurodegenerative diseases: the virtues of proteins that can save dying neurons
Diseases characterized by neurodegeneration affect individuals over 50 years of age and they attack one particular class of neurons in the brain or spinal cord. The research interest of Professor Ann Kato and her team is principally focalized on ALS in which there is a progressive paralysis caused... view more (2002-01-25)

Cold Spring Harbor Laboratory Scientists Devise Potential Approach To Treat Spinal Muscular Atrophy
In the neuromuscular disease called spinal muscular atrophy, or SMA, a protein deficiency caused by a single gene mutation leads to serious damage in growing nerve cells and the muscles they control.   view more (2008-04-07)

Treatment extends survival in mouse model of spinal muscular atrophy
Drug therapy can extend survival and improve movement in a mouse model of spinal muscular atrophy (SMA), new research shows. The study, carried out at the NIH's National Institute of Neurological Disorders and Stroke (NINDS), suggests that similar drugs might one day be useful for treating human... view more (2007-02-23)

Study Examines Role of Helicobacter Pylori in Esophageal Cancer Development
Infection with bacteria that can cause peptic ulcers and distal stomach cancer may be associated with a reduced risk of a type of esophageal cancer called adenocarcinoma, according to a study in the March 3 issue of the Journal of the National Cancer Institute. However, that same study found that... view more (2004-03-03)

Drug blocks lethal motor-neuron disease in mice
Spinal muscular atrophy (SMA) is an inherited motor-neuron disease that, in its most severe form, leads to death before 2 years of age and for which there is no treatment.   view more (2007-02-23)

Researchers discover molecular basis of a form of muscular dystrophy
A team of French and German researchers report in the May 2008 print issue of The FASEB Journal (http://www.fasebj.org) that people with limb-girdle muscular dystrophy are missing a protein called c-FLIP, which the body uses to prevent the loss of muscle tissue.   view more (2008-04-30)

Neurological disease raises risk of complications from flu
As another flu season approaches, patients with neurological and neuromuscular disease are especially vulnerable to respiratory failure caused by influenza.   view more (2005-11-02)

Early cardiac screening necessary for muscular dystrophy patients
Early diagnosis and treatment of heart disease may lead to longer life in Duchenne and Becker muscular dystrophy patients.   view more (2005-10-31)

Mice models developed at UCSD to benefit patients with multiple system atrophy
Researchers at the University of California, San Diego (UCSD) School of Medicine have developed a series of transgenic mouse models of multiple system atrophy, a progressive, fatal neurological disorder.   view more (2005-11-17)

PET-CT detects muscular lymphoma better than CT
PET-CT is better for early detection of muscular lymphoma than CT alone, according to a new study conducted by radiologists at the University of Minnesota in Minneapolis.   view more (2007-05-07)

Media Invite: Spinal Research Centre Open Day 7th July
Director of the Spinal Research Centre, Professor Michael Craggs, is hosting an open day of the Spinal Research Centre at the Royal National Orthopaedic Hospital, Stanmore. The research strategy of the SRC is based upon a number of key research programmes, which cover all aspects of the needs of... view more (2004-07-05)

Media invitation: Groundbreaking spinal injury therapy to be showcased in new exhibition
In response to a recent study published by a team of doctors from Imperial College London and Charing Cross hospital, the Science Museum in London has created a mini exhibition exploring magnetic therapy. The recent study found early evidence that administration of magnetic stimulation to the... view more (2004-05-20)

New therapeutic insight into duchenne muscular dystrophy
In the April 1st issue of Genes & Development, Dr. Bruce Spiegelman (Dana Farber Cancer Institute) and colleagues identify a key genetic component of and possible therapeutic target for Duchenne muscular dystrophy.   view more (2007-04-02)

Neurons grown from embryonic stem cells restore function in paralyzed rats
For the first time, researchers have enticed transplants of embryonic stem cell-derived motor neurons in the spinal cord to connect with muscles and partially restore function in paralyzed animals.   view more (2006-06-21)

Long-term use of mechanical ventilation contributes to the deterioration of human diaphragm muscle
A new study by University of Pennsylvania School of Medicine shows, for the first time in humans, that ventilators combined with diaphragm disuse contributes to muscle atrophy in the diaphragm in as little as eighteen hours.   view more (2008-03-27)

Human stem cell transplants mature into neurons and make contacts in rat spinal cord
Human nerve stem cells transplanted into rats' damaged spinal cords have survived, grown and in some cases connected with the rats' own spinal cord cells in a Johns Hopkins laboratory, overturning the long-held notion that spinal cords won't allow nerve repair.   view more (2007-02-14)

Mimicking a human disease in mice: a new model for the Parkinson related illness multiple system atrophy
In this month`s issue of EMBO Reports Kahle et al. describe how they genetically engineered a mouse to show pathological symptoms similar to those of human patients suffering from the neural disease Multiple System Atrophy (MSA), also known as Shy-Drager-Syndrome. The model could help researchers... view more (2002-06-06)

Electric Therapy helps Muscle Spasticity
Researchers in Austria who have been trying to overcome spasticity in people with spinal cord injury have made significant progress that might, in the future, help patients to stand. A technique called spinal cord stimulation is showing promise for people whose legs are bent and stiffened due to... view more (2002-10-24)

Researchers discover treatment for spinal cord injury pain
Spinal cord injury patients with moderate to severe nerve pain experienced less pain and in some cases no pain while taking the drug pregabalin.   view more (2006-11-28)

Stem cells - a cure for fatal muscular dystrophy
The diagnosis 'muscular dystrophy' is usually tantamount to a death sentence for those affected. One in three thousand male babies suffer from this incurable hereditary disease. The progress of the disease can only be slowed down through physiotherapy and medication. Scientists at Bonn University... view more (2002-07-04)

Purdue researchers find 'switch' for skeletal-muscle atrophy
Researchers in Purdue University's School of Veterinary Medicine have discovered genetic and drug-treatment methods to arrest the type of muscle atrophy often caused by muscle disuse, as well as aging and diseases such as cancer.   view more (2006-05-25)

MRC Research Offers Hope of Treatment for People with Duchenne Muscular Dystrophy
A new approach which effectively patches over genetic defects offers hope of treatment to people with the terminal illness, Duchenne muscular dystrophy. This is the conclusion of research led by Dr Qi Long Lu and Professor Terence Partridge at the Medical Research Council's Clinical Sciences... view more (2003-07-04)
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