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Spinal Muscular Atrophy Current Events | Spinal Muscular Atrophy News | 11

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Novel stem cell technology leads to better spinal cord repair
Researchers believe they have identified a new way, using an advance in stem-cell technology, to promote recovery after spinal cord injury of rats, according to a study published in today's Journal of Biology.   view more (2006-04-28)

First demonstration of muscle restoration in an animal model of Duchenne muscular dystrophy
Using a new type of drug that targets a specific genetic defect, researchers at the University of Pennsylvania School of Medicine, along with colleagues at PTC Therapeutics Inc. and the University of Massachusetts Medical School, have for the first time demonstrated restoration of muscle function in a mouse model of Duchenne's muscular dystrophy... view more... (2007-04-23)

Aggressive heart pacing may work best in some spinal cord patients
Patients with recurring problems with the heart slowing or stopping after a neck injury damages their cervical spinal cord may need aggressive therapy to avoid further cardiovascular problems and even death, Medical College of Georgia researchers say.   view more (2006-07-24)

Spinal cord bridge bypasses injury to restore mobility
The body's spinal cord is like a super highway of nerves. When an injury occurs, the body's policing defenses put up a roadblock in the form of a scar to prevent further injury, but it stops all neural traffic from moving forward.   view more (2006-08-21)

Gradient guides nerve growth down spinal cord
The same family of chemical signals that attracts developing sensory nerves up the spinal cord toward the brain serves to repel motor nerves, sending them in the opposite direction, down the cord and away from the brain.   view more (2005-08-15)

Robo-bats with metal muscles may be next generation of remote control flyers
Tiny flying machines can be used for everything from indoor surveillance to exploring collapsed buildings, but simply making smaller versions of planes and helicopters doesn't work very well.   view more (2009-07-07)

Drugs to bulk up muscles may make injuries more likely
Block the action of a protein that normally regulates muscle mass, and watch your muscles grow.   view more (2008-01-23)

Drug studied as possible treatment for spinal injuries
Researchers have shown how an experimental drug might restore the function of nerves damaged in spinal cord injuries by preventing short circuits caused when tiny "potassium channels" in the fibers are exposed.   view more (2009-11-20)

Medical breakthrough for organ transplants and cardiovascular diseases by Flemish researchers
When a blood vessel clogs up, a localized deficiency of oxygen results, causing the surrounding tissue to die. However, working with mice, VIB scientists connected to the Katholieke Universiteit Leuven have been able to prevent muscular tissue with severe hypoxia from dying.   view more (2008-01-07)

Further evidence showing treatment benefits of beta interferon for multiple sclerosis (pp 1463, 1489)
Results of a European study in this week's issue of THE LANCET provide further evidence that patients with early symptoms of multiple sclerosis given a weekly injection with interferon beta are less likely to progress to full clinical disease after two years follow-up. The study showed that the drug reduced patients' loss of brain tissue compared... view more... (2004-10-20)

A stronger backbone: DHEA hormone replacement increases bone density in older women
Taking a DHEA supplement combined with vitamin D and calcium can significantly improve spinal bone density in older women, according to a new study from a Saint Louis University scientist and his colleagues at Washington University.   view more (2009-05-12)

Zinc plays important role in brain circuitry
To the multitude of substances that regulate neuronal signaling in the brain and spinal cord add a new key player: zinc. By engineering a mouse with a mutation affecting a neuronal zinc target, researchers have demonstrated a central role for zinc in modulating signaling among the neurons.   view more (2006-11-27)

Rutgers University Scientist's Research Reveals Critical Knowledge About the Nervous System
Uncover the neural communication links involved in myelination, the process of protecting a nerve's axon, and it may become possible to reverse the breakdown of the nervous system's electrical transmissions in such disorders as multiple sclerosis, spinal cord injuries, diabetes and cancers of the nervous system.   view more (2007-11-07)

Uric acid and spinal cord injury treatment
Uric acid is commonly associated with the excruciatingly painful joint disease known as gout, but it can also play a crucial role in the treatment of spinal cord injury and other central nervous system disorders, such as stroke, multiple sclerosis and Parkinson's disease, according to Rutgers' Bonnie Firestein.   view more (2007-01-04)

Human stem cells delay start of Lou Gehrig's disease in rats
Researchers at Johns Hopkins have shown that transplanting human stem cells into spinal cords of rats bred to duplicate Lou Gehrig's disease delays the start of nerve cell damage typical of the disease and slightly prolongs life.   view more (2006-10-16)

Nanotechnology offers hope for treating spinal cord injuries, diabetes, and Parkinson's disease
Imagine a world where damaged organs in your body—kidneys, liver, heart—can be stimulated to heal themselves. Envision people tragically paralyzed whose injured spinal cords can be repaired. Think about individuals suffering from the debilitating effects of Parkinson's or Alzheimer's relieved of their symptoms - completely and... view more... (2007-04-23)

New roles for growth factors: Enticing nerve cells to muscles
During embryonic development, nerve cells hesitantly extend tentacle-like protrusions called axons that sniff their way through a labyrinth of attractive and repulsive chemical cues that guide them to their target.   view more (2006-06-16)

CU-Boulder research team identifies stem cells that repair injured muscles
A University of Colorado at Boulder research team has identified a type of skeletal muscle stem cell that contributes to the repair of damaged muscles in mice, which could have important implications in the treatment of injured, diseased or aging muscle tissue in humans, including the ravages of muscular dystrophy.   view more (2009-03-06)

Myelin suppresses plasticity in the mature brain
Yale School of Medicine researchers report in Science this week genetic evidence for the hypothesis that myelination, or formation of a protective sheath around a nerve fiber, consolidates neural circuitry by suppressing plasticity in the mature brain.   view more (2005-09-30)

Possible brain hormone may unlock mystery of hibernation
The discovery of a possible hibernation hormone in the brain may unlock the mystery behind the dormant state, researchers reported in the April 7, 2006 issue of Cell.   view more (2006-04-06)
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