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A possible risk group for statin use
In a patient study of over 1,000 individuals with coronary artery disease (CAD), researchers have found that high levels of an enzyme called PLTP significantly increased the risk of heart attack in the subset of patients taking statins. While follow-up studies will be needed to tease out the exact connection between PLTP and statins, this... view more... (2009-03-24)
EZETROL® Co-Administration with Statin Therapy Results in Greater LDL Cholesterol Lowering and Goal Attainment for Patients with Diabetes and Metabolic Syndrome, Studies Reveal
Results from two new clinical trials show that patients with diabetes and metabolic syndrome who are treated with ezetimibe (EZETROL®) co-administered with a statin experience greater reductions in LDL ("bad") cholesterol, compared to patients taking a statin alone. The new data also demonstrates that patients with diabetes and... view more... (2004-09-07)
Statins Benefit Older People (pp 1618, 1623)
Elderly people at high risk of cardiovascular disease could benefit substantially by treatment with statins, cholesterol-lowering drugs with known effectiveness among middle-aged people at risk of heart disease and stroke, conclude authors of a study in this week's issue of THE LANCET. James Shepherd from the University of Glasgow, UK, and... view more... (2002-11-20)
Cholesterol-lowering drugs not associated with increased breast cancer risk
A report being published in the Journal of the National Cancer Institute found that women who took statins-the widely used cholesterol lowering drugs-do not face an increased breast cancer risk as had been suggested by some previous studies. view more (2006-05-17)
Statins show dramatic drug and cell dependent effects in the brain
Besides their tremendous value in treating high cholesterol and lowering the risk of heart disease, statins have also been reported to potentially lower the risks of other diseases, such as dementia. view more (2009-10-29)
Vitamin B niacin offers no extra benefit to statin therapy in seniors already diagnosed with CAD
The routine prescription of extended-release niacin, a B vitamin (1,500 milligrams daily), in combination with traditional cholesterol-lowering therapy offers no extra benefit in correcting arterial narrowing and diminishing plaque buildup in seniors who already have coronary artery disease, a new vascular imaging study from Johns Hopkins experts... view more... (2009-11-18)
Most Cardiologists Believe That LDL Cholesterol Should Be Lowered
Beyond Current Guidelines for Patients with Risk Factors, Reveals New Pan-European Survey view more (2004-08-31)
Fish oil and red yeast rice studied for lowering blood cholesterol
A great deal of scientific evidence shows that cholesterol-reducing medications known as statins can help prevent coronary artery disease. view more (2008-07-09)
Statin therapy associated with regression of coronary atherosclerosis with key lipid level changes
An analysis of data from four clinical trials suggests that statin therapy is associated with regression of coronary atherosclerosis when low-density lipoprotein cholesterol (LDL-C or "bad" cholesterol) is substantially reduced and high-density lipoprotein cholesterol (HDL-C or "good" cholesterol) is increased, but it remains... view more... (2007-02-07)
Relationship between statins and cognitive decline more complex than thought
Previous explorations of a link between statins, a cholesterol lowering medication, and cognitive decline have produced inconsistent results. view more (2007-11-06)
Call for removal of Crestor (p 2189)
The author of a letter in this week's issue of THE LANCET is calling for the removal of the statin rosuvastatin (Crestor) from the drug market, based on data suggesting that it has a poorer safety profile than other licensed statin drugs. A Lancet editorial (Lancet 2003; 362: 1341) voiced concerns about the high-profile marketing of rosuvastatin... view more... (2004-06-23)
No evidence that widely prescribed statins protect against prostate cancer
A large community-based study refutes previous findings that statins - a top-selling drug class, worldwide -- might cut one's risk of developing prostate cancer by reducing production of the male hormones that fuel cancer growth. view more (2007-08-10)
Early end to key study on benefits of niacin, a B vitamin, in keeping arteries open was premature
Heart experts at Johns Hopkins are calling premature the early halt of a study by researchers at Walter Reed Army Medical Center and Washington Hospital Center on the benefits of combining extended-release niacin, a B vitamin, with cholesterol-lowering statin medications to prevent blood vessel narrowing. view more (2009-11-16)
Statins benefit for kidney-transplant patients
Embargo: 0001 H (London time) Tuesday 3 June 2003. Authors of a study published on THE LANCET'S website today (www.thelancet.com) highlight how statins (cholesterol-lowering drugs) could offer protection against cardiovascular disease for people who have undergone kidney transplantation. Kidney-transplant patients are at an increased risk of... view more... (2003-05-30)
Stopping statins after stroke raises risk of death, dependency
People who stopped taking cholesterol-lowering drugs after being hospitalized for a stroke are at greater risk of death or dependency within three months of the stroke. view more (2007-08-28)
UK study suggests statins may reduce diabetes risk
For the first time a statin drug has been shown to reduce the risk of type 2 diabetes, according to a UK study published in the latest issue of Circulation: Journal of the American Heart Association. A research team led by Allan Gaw, director of the Clinical Trials Unit at Glasgow Royal Infirmary, analysed data from the West of Scotland Coronary... view more... (2001-01-22)
Study indicates cancer preventive effect for statins
The commonly used prescription statin drugs may have a protective effect in the prevention of liver cancer and lead to a reduction in the need for gallbladder removals, according to two studies published in Gastroenterologyiption statin drugs may have a protective effect in the prevention of liver cancer and lead to a reduction in the need for... view more... (2009-05-06)
Researchers find specific statin significantly reduces Alzheimer's and Parkinson's disease risk
Researchers from Boston University School of Medicine (BUSM) have found that the statin, simvastatin, reduces the incidence of Alzheimer's disease and Parkinson's disease by almost 50 percent. view more (2007-07-19)
One size does not fit all
Statins, a commonly prescribed class of drugs used by millions worldwide to effectively lower blood cholesterol levels, may actually have a negative impact in Multiple Sclerosis (MS) patients treated with high daily dosages. view more (2009-05-26)
MSU researcher studies ties between cholesterol drugs, muscle problems
A Michigan State University researcher is studying whether the most popular class of cholesterol-lowering drugs may cause muscle problems in users. view more (2008-11-12)
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