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Stem Cell | Stem Cell News, Research and Current Events
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UK leads race to produce world's first clinical grade stem cells
The University of Sheffield has received a £2.6m grant to create some of the world's first embryonic stem cell lines that can be used for medicinal purposes.   view more (2005-03-16)

Stem cell identity in culture may strongly depend on the cellular microenvironment
Identification, isolation and large scale culture of stem cells for potential medical applications is a major challenge in cell biology.   view more (2007-04-25)

Xie Lab demonstrates the role of microRNA pathway
Ting Xie, Ph.D., Associate Investigator, and Zhigang Jin, Ph.D., Postdoctoral Research Associate in the Xie Lab, have published results showing that the microRNA pathway is essential for controlling self-renewal of germline stem cells and somatic stem cells in the Drosophila ovary.   view more (2007-02-16)

'It is time for scientists to make the case for stem-cell research' (p 113)
Stem-cell research-and its political, legal, and ethical implications-is the theme of this week's issue of THE LANCET. An editorial comments how scientists need to step forward and engage the public to make the case for the future benefits of stem-cell research. 'But convincing critics of the... view more (2004-07-07)

U of MN researchers use human embryonic stem cells to kill cancer cells
For the first time, stem cell researchers at the University of Minnesota have coaxed human embryonic stem cells to create cancer-killing cells in the laboratory, paving the way for future treatments for various types of cancers (or tumors).   view more (2005-10-12)

Faults in newly discovered breast stem cells may lead to tumours
Victorian Breast Cancer Research Consortium scientists from The Walter and Eliza Hall Institute, using a mouse model, have discovered the rare stem cell that drives the formation of all breast tissue.   view more (2006-01-05)

Hopes for new cell therapies 'stem' from Sheffield
The Centre for Stem Cell Biology (CSCB) at the University of Sheffield is welcoming some of the world's leading experts to its International Human Embryonic Stem Cell Symposium on Friday 9 July 2004. The CSCB is a world-leading centre for stem cell research, and has produced two of the UK's six... view more (2004-07-06)

Scientists find stem cell switch
Scientists have discovered how plant stem cells in roots detect soil structure and whether it is favourable for growth.   view more (2007-07-27)

ESC Congress 2004: Converting cells into heart muscle
Bone marrow derived stem cells can give rise to heart muscle cells. This plasticity concept - the ability of bone marrow cell to transdifferentiate into heart muscle cell - is supported by experimental and clinical data. Another possibility is to replace the missing function by causing... view more (2004-08-30)

Agreement reached on an international human stem cell project
An international project to co-ordinate human stem cell research across the globe was agreed at a 12-country* International Stem Cell Forum meeting chaired by the Medical Research Council (MRC) on Friday 11 July. Stem cell therapy is a potentially revolutionary way to repair diseased and damaged... view more (2003-07-15)

Statement from the European Life Sciences Group
The promises and concerns engendered by stem cell research triggered debate world-wide. European citizens realise the significance of these issues and expect guidance to deal with them. The European Life Sciences Group thanks the European Commission and the European Commissioner for Research,... view more (2001-12-19)

The European Science Foundation publishes policy briefing for human stem cell research
The policy paper recommends the permission of studies of stem cells from embryos and adults, reproductive cloning should not be permitted, but therapeutic cloning should be allowed. There are many chronic, serious and disabling human diseases such as, Parkinson's Disease, Cystic Fibrosis and... view more (2001-06-25)

Isolation of a new gene family essential for early development
Researchers at BRIC, University of Copenhagen, have identified a new gene family (UTX-JMJD3) essential for embryonic development. The family controls the expression of genes crucial for stem cell maintenance and differentiation, and the results may contribute sig-nificantly to the understanding of... view more (2007-08-23)

Columbia University Medical Center researchers discover potential mechanism for tumor growth
Researchers at Columbia University Medical Center have identified an inherent feature of stem and progenitor cells that may promote initiation and progression of cancerous tumors.   view more (2005-12-16)

Great potential for new success in Swedish stem cell research
Swedish stem cell researchers are in a good position to become even more successful than in recent years. This can be achieved by improving the collaboration between research groups, and by increasing the number of researchers in the field through, for example, the introduction of... view more (2002-03-21)

Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state
For more than 25 years, stem cells have been defined based on what they can become: more of themselves, as well as multiple different specialized cell types.   view more (2007-06-20)

When is a stem cell not really a stem cell?
Working with embryonic mouse brains, a team of Johns Hopkins scientists seems to have discovered an almost-too-easy way to distinguish between "true" neural stem cells and similar, but less potent versions.   view more (2007-08-27)

Tapping into spinal cures
Stem cells which give rise to vertebrae, muscle and the spinal cord have been identified for the first time by Dr. Valerie Wilson (University of Edinburgh). "These axial stem cells could be used in the future to help replace damaged tissues after back injuries", says Dr. Wilson who will... view more (2004-03-26)

U of MN researchers identify new cord blood stem cell
Researchers at the University of Minnesota Medical School have discovered a new population of cells in human umbilical cord blood that have properties of primitive stem cells.   view more (2006-02-14)

New stem-cell findings can help the body to cure itself
Researchers at Karolinska Institutet have identified an important mechanism that regulates how many new cells are produced by each intestinal stem cell. The study is published in the latest issue of the prestigious scientific journal, Cell.   view more (2006-06-16)

Mount Sinai Hospital researcher develops Canada's first embryonic stem cell lines
A senior scientist at Mount Sinai Hospital has developed Canada's first two human embryonic stem cell lines, giving researchers across the country new potential and hope for eventually discovering treatments and cures for many chronic and fatal diseases.   view more (2005-06-08)

Stem-cell therapy could have benefits and risks for heart-attack patients (pp 746, 751, 783)
Two studies in this week's issue of THE LANCET raise questions about the feasibility and safety of stem-cell therapy for heart disease, suggesting that such treatments could have both benefits and drawbacks. Adult haemopoietic stem cells give rise to blood cells, and are thought to be able to... view more (2004-03-03)

Cell division studies hint at future cancer therapy
When a cell's assets get divided between daughter cells, Dr. Quansheng Du wants to make sure both offspring do well.   view more (2008-01-23)

Stem cells and cancer: cancer pathways that also control the adult stem cell population
Speaking today (10 April) at the UK National Stem Cell Network Annual Science Meeting in Edinburgh, Professor Alan Clarke from Cardiff University describes his work to investigate a mechanism that normally drives adult stem cells to repair the intestine.   view more (2008-04-10)

GABA halts stem cell production in the brain
Release of the neurotransmitter GABA by adult neuronal precursor cells that develop into neurons limits stem cell proliferation, according to a study at Yale School of Medicine in the September issue of Nature Neuroscience.   view more (2005-09-02)

New U of T strategy will boost cord blood stem cells
A team of bioengineers led by the University of Toronto has discovered a way to increase the yield of stem cells from umbilical cord blood, to an extent which could broaden therapeutic use of these cells.   view more (2005-10-19)

Heart derived stem cells develop into heart muscle
Dutch researchers at University Medical Center Utrecht and the Hubrecht Institute have succeeded in growing large numbers of stem cells from adult human hearts into new heart muscle cells.   view more (2008-04-24)

Signaling for cartilage
Skeletal progenitor cells differentiate into cartilage cells when one master gene actually suppresses the action of another, said Baylor College of Medicine researchers in a report that appears online in the journal Proceedings of the National Academy of Sciences.   view more (2006-11-28)

Master regulatory gene of epithelial stem cells identified
The skin's ability to replace the tissue it sloughs off is controlled by a variety of genes. A new study from Harvard Medical School published in the May 4 issue of Cell, however, identifies a "master regulator" of this regeneration process not only for skin, but for many epithelial... view more (2007-05-04)

Use eggs, not embryos, to derive stem cells, say researchers
Concerns about the ethics of using embryos created to treat infertile couples for stem cell research is discussed by researchers at St Mary's Hospital, Manchester in this week's BMJ. Although the Human Fertilisation and Embryology Act 1990 allows the creation of embryos for research in the United... view more (2003-10-08)

Discovery suggests why stem cells run through stop signs
Everyone knows that stem cells are controversial. Many people know that stem cells can grow into virtually any cell type found in the body, from a red blood cell to a muscle cell to a brain cell. But no one really knows why stem cells continue to divide and renew themselves long after the point... view more (2005-06-13)

Heart stem cell scientist to honor pioneering woman scientist in keynote speech
Professor Christine Mummery, one of the world's leading heart stem cell experts, will later today (9 April) honour the memory of Dame Anne McLaren in the keynote lecture of the inaugural UK National Stem Cell Network Science Meeting in Edinburgh.   view more (2008-04-10)

Donor T cells change the fate of stem cells in transplantation
When a transplant patient suffers complications such as graft rejection or graft-versus-host disease, physicians attempt to stop the body's immune response by targeting a patient's T cells.   view more (2006-07-13)

How stem cells are regulated
Researchers from Biotech Research & Innovation Centre (BRIC) at University of Copenhagen have identified a new group of proteins that regulate the function of stem cells. The results are published in the new issue of Cell.   view more (2007-02-23)

US funding for Lund research for project on adult stem cells
Adult stem cells are to be treated so that they develop characteristics of nerve cells and can produce dopamine, according to Associate Professor Jia-Yi Li at the Wallenberg Neuro Center at Lund University, who has received a grant of some SEK 2 million from the National Institutes of Health (NIH),... view more (2003-01-29)

DFG remains skeptical of the cloning of human cells
According to a paper published in the journal Stem Cells, an American group has succeeded in inserting cell nuclei from human skin cells into human enucleated oocytes and to stimulate these new cells to undergo cell division in the laboratory.   view more (2008-01-23)

Post brain injury: New nerve cells originate from neural stem cells
Most cells in the human brain are not nerve cells, but supporting cells (glial cells). They serve as a framework for nerve cells and play an important role in the wound reaction that occurs with injuries to the brain.   view more (2008-03-12)

Controlling embryonic fate by association
Association determines fate in embryonic stem cells, said Baylor College of Medicine researchers in a report that appears in the current issue of the journal Nature Cell Biology.   view more (2008-05-05)

Master regulatory gene found that guides fate of blood-producing stem cells
Researchers from the University of Pennsylvania School of Medicine found that a protein called NF-Ya activates several genes known to regulate the development of hematopoietic stem cells (HSC), or blood-producing stem cells, in bone marrow.   view more (2005-08-02)

Minimal cocktail for growing human embryonic stem cells established
Researchers at Yale have established the minimal nutritional requirements for growing and maintaining human embryonic stem cells, a recipe that is critical for clinical application and for developmental studies.   view more (2006-03-28)

Epigenetics to shape stem cell future
Everyone hopes that one day stem cell-based regenerative medicine will help repair diseased tissue.   view more (2007-02-20)

Liquid crystals show promise in controlling embryonic stem cells
Liquid crystals, the same phase-shifting materials used to display information on cell phones, monitors and other electronic equipment, can also be used to report in real time on the differentiation of embryonic stem cells.   view more (2006-03-08)

Neural stem cells derived from human embryonic stem cells carry abnormal gene expression
Neural stem cells grown from one of the federally approved human embryonic stem cell lines proved to be inferior to neural stem cells derived from fetal tissue donated for research, a UCLA study has found.   view more (2006-08-07)

Stem cell transplantation procedure results in long-term survival for amyloidosis patients
Researchers from the Stem Cell Transplant Program and the Amyloid Treatment and Research Program at Boston University Medical Center (BUMC) have found that high-dose chemotherapy and blood stem cell transplantation can result in long-term survival for patients diagnosed with primary systemic light... view more (2007-08-08)

Cancer stem cells can go it alone
At the heart of most, if not all cancers, lie a handful of wayward stem cells that feed the ever growing tumor mass, but their scarcity make it difficult for scientists to study them.   view more (2007-06-12)

Study: Donated embryos could result in more than 2,000 new embryonic stem cell lines
In a survey of more than one thousand infertility patients with frozen embryos, 60 percent of patients report that they are likely to donate their embryos to stem cell research.   view more (2007-06-21)

Progress being made in exploring potential use of stem cells to treat heart disease
Scientists are making headway in exploring the potential future use of stem cells to treat heart disease, according to a review article in the current issue of Nature (June 29, 2006).   view more (2006-06-29)

Researchers Find Defects in Adult Stem Cell Niche May Cause Breast Cancer
Researchers at Georgetown's Lombardi Comprehensive Cancer Center have found that the onset of breast cancer may be due to defects in somatic adult stem cell niches that exist long before tumors develop.   view more (2005-10-05)

Forsyth scientists gain new understanding of adult stem cell regulation
Forsyth Institute scientists have discovered an important mechanism for controlling the behavior of adult stem cells. Research with the flatworm, planaria, found a novel role for the proteins involved in cell-to-cell communication.   view more (2007-08-01)

Researchers first to map gene that regulates adult stem cell growth
A new discovery in stem cell research may mean big things for cancer patients in the future. Gary Van Zant, Ph.D., and a research team at the University of Kentucky published their findings today in Nature Genetics, an international scientific journal.   view more (2007-01-15)
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