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Liver regeneration may be simpler than previously thought
The way the liver renews itself may be simpler than what scientists had been assuming. A new study, appearing in the April 13 issue of The Journal of Biological Chemistry, provides new information on the inner workings of cells from regenerating livers that could significantly affect the way... view more (2007-04-12)

Cells on path to becoming mature T-cells more flexible than commonly thought
Contrary to the currently accepted model of T-cell development, researchers at the University of Pennsylvania School of Medicine have found that juvenile cells on their way to becoming mature immune cells can develop into either T cells or other blood-cell types versus only being committed to the... view more (2008-04-10)

Studies attribute recent increase in multiple myeloma survival to novel therapies
Multiple myeloma is one of the most common and devastating bone marrow cancers in the U.S., but survival rates have risen dramatically over the past decade.   view more (2007-11-02)

Researchers Discover New Factor in Nerve Regeneration
Researchers in Oxford University's Department of Human Anatomy have identified a factor involved in the regeneration of neurons in the central nervous system. The discovery and use of this factor could provide the basis for a reparative treatment for both brain and spinal cord injuries. Unlike... view more (2003-04-07)

New telomere discovery could help explain why cancer cells never stop dividing
A group working at the Swiss Institute for Experimental Cancer Research (ISREC) in collaboration with the University of Pavia has discovered that telomeres, the repeated DNA-protein complexes at the end of chromosomes that progressively shorten every time a cell divides, also contain RNA.   view more (2007-10-05)

Toxins in cigarette smoke prevent stem cells from becoming cartilage
A toxic pollutant spread by oil spills, forest fires and car exhaust is also present in cigarette smoke, and may represent a second way in which smoking delays bone healing, according to research presented today at the annual meeting of the Orthopaedic Research Society in San Francisco.   view more (2008-03-04)

Nerve prosthesis developed in Ume'å
The first clinical study ever with a new type of nerve prosthesis has been launched at Northern Sweden University Hospital. It is being carried out by a research team from Ume'å University under the leadership of Professors Jan-Olof Kellerth and Mikael Wiberg. The team, at the Department of... view more (2003-11-11)

Genetics Policy Institute leads global battle to head off UN ban of therapeutic cloning on Dec 8 - Response to US led stealth campaign
Coral Gables, Florida - (December 1, 2003): The Genetics Policy Institute (GPI) has organized a worldwide grassroots campaign to oppose any efforts in the United Nations to institute a ban of therapeutic cloning. This comes following the revelation that the United States and countries supporting a... view more (2003-12-01)

CELL TRANSPLANTATION COULD RESTORE CARDIAC FUNCTION AFTER HEART ATTACK (p 491)
Issue 8 February 2003 Embargoed 0001 h (London time) 7 February 2003 French authors of a research letter in this week's issue of THE LANCET describe the preliminary success of transplanting muscle stem-cells from the thigh to the heart to restore damaged cardiac tissue after heart attack. The... view more (2003-02-05)

Researchers mimic vascular system to nourish engineered tissue for transplants
One day soon, laboratories may grow synthetically engineered tissues such as muscle or cartilage needed for transplants. In a major step forward, Cornell engineers describe in the journal Nature Materials a microvascular system they have developed that can nourish growing tissues.   view more (2007-10-09)

Guidance of Primordial Germ Cell Migration by the Chemokine SDF-1
Identification of the molecular cues governing cell migration is of major importance for the understanding of tissue and organ development and for therapy in cases of diseases resulting from aberrant cell movement. Primordial Germ Cell (PGC) migration is a useful model for studying directional cell... view more (2002-11-27)

Scientists identify genomic 'fingerprint' for alcohol-induced heart failure
A person with dilated cardiomyopathy has an enlarged and stretched heart cavity, usually too weak to pump normally; most people will go on to develop heart failure.   view more (2008-05-05)

Cell phone use not linked to cancer risk
Long or short-term cell phone use is not associated with increased cancer risk, according to a study in the December 6 issue of the Journal of the National Cancer Institute.   view more (2006-12-06)

New Cell Transplantation Technique Restores Insulin Production in Diabetics
Researchers are using a new cell transplantation technique to restore the cells that produce insulin in patients with type 1 diabetes. The method is minimally invasive, with few complications.   view more (2005-11-30)

U of M Sets Course For Cure of Fatal Childhood Skin Disease
Physicians at the University of Minnesota and University of Minnesota Children's Hospital, Fairview have set the path to a cure for a young boy's fatal genetic skin disease, recessive dystrophic epidermolysis bullosa (RDEB), by using a cord blood and bone marrow transplant. Nate Liao, a... view more (2008-06-04)

UCLA researchers observe how the immune system recognizes and responds to cancer
Using positron emission tomography (PET) imaging, researchers at UCLA's Jonsson Cancer Center were able to observe-in real time-how the immune system initially recognizes cancer and mobilizes to fight the disease.   view more (2005-11-15)

Gene mutation improves leukemia drug's effect
Gene mutations that make cells cancerous can sometimes also make them more sensitive to chemotherapy. A new study led by cancer researchers at Ohio State University shows that a mutation present in some cases of acute leukemia makes the disease more susceptible to high doses of a particular... view more (2008-06-18)

MiRNA Fingerprint Identified in Platelet Formation
Scientists have identified a handful of microRNAs (miRNAs) that appear to play a significant role in the development of platelets - blood cells critical to the body's ability to form clots following an injury.   view more (2006-03-17)

Same process discovered to both form skeleton and protect it for life
A protein signaling pathway recently discovered to guide the formation of the skeleton in the fetus also keeps bones strong through adult life, according to two papers published recently in the journal Nature Medicine.   view more (2008-03-13)

UC Davis researchers move biotechnology closer to replacing electronic pacemakers
UC Davis researchers have successfully used a custom designed protein and gene delivery system to restore normal heart rhythms in pigs with electronic pacemakers, reducing their dependence on implanted devices.   view more (2006-08-23)

Electroacupuncture at PC6 may decrease frequency of transient lower esophageal sphincter relaxation
The First Hospital of Peking University, China-Research, has shown that electroacupuncture at PC6 may decrease the frequency of transient lower esophageal sphincter relaxation (TLESR), which is the main mechanism underlying gastroesophageal reflux disease (GERD).   view more (2007-10-11)

MicroRNA tweaks protein that controls early heart development
Researchers at UT Southwestern Medical Center have discovered how a small molecule of RNA called microRNA - a chemical cousin of DNA - helps fine tune the production of a key protein involved in the early development of heart muscle.   view more (2005-06-13)

Startling results from new biomedical research international conference will smooth path to the market place
Researchers have discovered how to convert liver cells of mice into pancreatic cells using a single injection. This may eventually lead to a cure for diabetes. Dr. James Mittra, one of the organisers of an international conference in Edinburgh on the Evolution of the Life Science Industries asks,... view more (2005-01-27)

Baumann lab identifies elusive telomere RNA subunit in single cell model
The Stowers Institute's Baumann Lab has identified the long-sought telomerase RNA gene in a single-cell research model. Their findings have been posted to the Web site of the journal Nature Structural & Molecular Biology and will appear in a future print edition.   view more (2007-12-28)

Immune deficiency linked to a type of eye cancer
The incidence of squamous cell eye cancer is greater among kidney transplant patients and people with human immunodeficiency virus (HIV) than the general public, which suggests the disease is associated with immune deficiency.   view more (2007-08-15)

UCSB researchers discover that the cell's endosomes use a surprising transportation system
Cells have developed a surprising transportation system for their endosomes, according to research published today in Physical Review Letters, "Dynamics and Spatial Organization of Endosomes in Mammalian Cells."   view more (2005-10-06)

St. Jude identifies the specific cell that causes eye cancer, disproving long-held theory
Investigators at St. Jude Children's Research Hospital have identified the cell that gives rise to the eye cancer retinoblastoma, disproving a long-standing principle of nerve growth and development.   view more (2007-10-19)

Using Nanoparticles, In Vivo Gene Therapy Activates Brain Stem Cells
Using customized nanoparticles that they developed, University at Buffalo scientists have for the first time delivered genes into the brains of living mice with an efficiency that is similar to, or better than, viral vectors and with no observable toxic effect, according to a paper published this... view more (2005-07-26)

Key to zebrafish heart regeneration uncovered
When a portion of a zebrafish's heart is removed, the dynamic interplay between a mass of stem cells that forms in the wound and the protective cell layer that covers the wound spurs the regeneration of functional new heart tissue.   view more (2006-11-03)

Cells from amniotic fluid used to tissue-engineer a new trachea
Researchers at Children's Hospital Boston report using tissue engineering to reconstruct defective tracheas (windpipes) in fetal lambs, first using cells from the amniotic fluid to grow sections of cartilage tube, and then implanting these living grafts into the lambs while still in the womb.   view more (2005-10-10)

The secret of internal bliss revealed
Scientists now know for sure how cannabis works in the brain. By studying naturally occuring cannabinoids they have found that cannabis 'speaks' to nerve cells instructing them to stop releasing their chemical neurotransmitters so dumbing down their effects. The upside is that it makes cannabis... view more (2001-04-03)

Researchers discover gene essencial to cerebellum formation
A study published this week in the scientific journal PNAS provides new information on the origin of different cells in the cerebellum, an important component of the central nervous system found in all vertebrates, including humans, and the part of the brain that controls movement.   view more (2007-03-07)

Researchers find roadmap to next-generation cancer therapies
Pinpointing new targets for cancer treatments is as difficult as finding a needle in a haystack, yet a University of Rochester team has discovered an entire novel class of genes they believe will lead to a greater understanding of cancer cell function and the next generation of effective and less... view more (2008-05-27)

Can pathological techniques help identify primary colorectal signet ring cell carcinoma?
Primary colorectal signet ring cell carcinoma is a rare but distinctive malignancy of the large bowel. More than 96% of signet ring cell carcinomas arise in the stomach, with the rest arising from other primary organs.   view more (2008-05-21)

Small protein may have big role in making more bone and less fat
A small protein may have a big role in helping you make more bone and less fat, researchers say.   view more (2008-07-02)

Largest study of unrelated bone marrow transplantation for leukemia serves as benchmark
Together with 16 other institutions in the United States, University of Minnesota researchers led the largest study to date in patients with leukemia and related disorders undergoing bone marrow transplantation from unrelated donors.   view more (2005-08-03)

DNA repair in mammal embryos is a matter of timing
Investigators at St. Jude Children's Research Hospital have discovered that the cells of the developing nervous system of the mammalian embryo have an exquisite sense of timing when it comes to fixing broken chromosomes: the cells use one type of repair mechanism during the first half of... view more (2006-06-20)

Super-thin Filter, 50 Atoms Thick, Sorts Individual Molecules
A newly designed porous membrane, so thin it's invisible edge-on, may revolutionize the way doctors and scientists manipulate objects as small as a molecule.   view more (2007-02-15)

A new method to clone mice: an important step in the research for applications in the human
A simplified method for cloning mice, which has recently resulted in live offspring, has been developed at the Ghent University. Although a few laboratories have been successful in breeding mice by cloning, this is the first report on cloning of an adult mammalian animal in Belgium and using a... view more (2000-12-18)

Mayo Clinic research shows promise for myeloma patients
Mayo Clinic Cancer Center investigators report that combination therapy with lenalidomide (RevlimidTM) and dexamethasone (combination is called Rev/Dex) looks like a breakthrough treatment for multiple myeloma.   view more (2005-09-02)

Gold nanoparticles may pan out as tool for cancer diagnosis
Purdue University researchers have created gold nanoparticles that are capable of identifying marker proteins on breast cancer cells, making the tiny particles a potential tool to better diagnose and treat cancer.   view more (2007-08-01)

U of M begins nation's first clinical trial using T-reg cells from cord blood in leukemia treatment
University of Minnesota researchers have initiated a ground breaking clinical trial to determine the optimal dose and safety of T regulatory cells (T-regs) to decrease the risk of immune reactions common in patients undergoing blood and marrow transplantation.   view more (2007-09-06)

Press release from Nature and the Nature Research Journals
This Press Release contains: ·Summaries of newsworthy papers: NANOSCALE ARMS CONTROL - Nature Materials STEPMOTHER OF PEARL - Nature Materials COMBINATION VACCINE DELIVERS DOUBLE BLOW - Nature Medicine STEM CELL ENGRAFTMENT SUCCESS DOES NOT ENSURE LONG-TERM SURVIVAL - Nature Immunology Mention of... view more (2003-05-27)

Brain tumor researchers find their 'niche'
Brain tumors appear to arise from cancer stem cells (CSCs) that live within microscopic protective "niches" formed by blood vessels in the brain; and disrupting these niches is a promising strategy for eliminating the tumors and preventing them from re-growing.   view more (2007-01-17)

UK scientists set their sights on cure for AMD
A groundbreaking surgical therapy capable of stabilising and restoring vision in the vast majority of patients who currently suffer blindness through Age-Related Macular Degeneration (AMD) is to be taken to clinical trial by scientists and clinicians at the UCL Institute of Ophthalmology,... view more (2007-06-06)

Striking the right balance between excitation and inhibition
Neurons in the brain and spinal cord come in two flavors, excitatory neurons that transmit and amplify signals, and inhibitory neurons that inhibit and refine those signals.   view more (2006-05-31)

Dengue Virus Reveals Its Circular Secret
The first step in the transmission of mosquito-borne viruses is no mystery: it's the pesky insect's bite that allows the virus to enter its victim's bloodstream. But for some of the most dangerous insect-borne viruses, details of what happens next have been unclear.   view more (2006-08-02)

Rong Li Lab demonstrates the process of mammalian egg maturation
he Rong Li lab team has answered an important question about how mammalian eggs undergo maturation through an intricate process of asymmetric cell division. The team discovered a novel pathway by which chromatin exerts command on the cell membrane to produce a specialized machinery used for cell... view more (2007-02-06)

Growth factor stimulates rapid extension of key motor neurons in brain
A growth factor known to be important for the survival of many types of cells stimulates rapid extension of corticospinal motor neurons - critical brain cells that connect the cerebral cortex with the spinal cord and that die in motor neuron diseases like amyotrophic lateral sclerosis (ALS or Lou... view more (2006-11-06)

The sap flow through trees.
The transport of water through trees Trees take up water from the soil by their root hairs and transport it through the vessels of the stem towards the leaves. At leaf level this water evaporates and comes into the atmosphere through little pores in the leaf epidermis, called stomates. This... view more (2003-04-29)
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